Inhibition of intimal hyperplasia by an antisense oligonucleotide of farnesyl transferase delivered endoluminally during iliac angioplasty in a rabbit model

Annals of Vascular Surgery

Volumn 11, Issue 6, 1997, Pages 581-587

  Chemla, E ^a   Castier, Y ^a   Julia, P ^a   Pirotski, E ^a   Carpentier, A ^a   Fabiani, J N ^a,b  

^a Hôpital Broussais ^*

^b HÔPITAL BROUSSAIS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; FARNESYL TRANS TRANSFERASE;

ANGIOPLASTY; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTERY INTIMA PROLIFERATION; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; GENE ACTIVATION; ILIAC ARTERY; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT;

EID: 0030663635     PISSN: 08905096     EISSN: None     Source Type: Journal    
DOI: 10.1007/s100169900095     Document Type: Article

References (35)

1. Baulers C, Hamon M, Belle EV, et al. Resténoses après angioplastie coronaire: Apport des modèles expérimentaux. Arch Mal Coeur 1993;86:47-56.
2. Dobrin P, Littoy D, Endean E. Mechanical factors predisposing to intimal hyperplasia and medial thickening in autogenous vein graft. Surgery 1989;105:393-400.
3. Ip J, Fuster V, Badimon L, et al. Syndromes of accelerated atherosclerosis: Role of vascular injury and smooth muscle proliferation. J Am Coll Cardiol 1990;15:1667-1687.
4. Ross R. The pathogenesis of atherosclerosis: A perspective for the 1990s. Nature 1993;362:801-809.
5. Bauters C. Apport de la biologie moléculaire à la compréhension et au traitement de la resténose après angioplastie. Réalités Cardiologiques 1993;49:12-18.
6. Reidy MA, Fingerle J, Lindner V. Factors controlling the development of arterial lesions after injury. Circulation 1992;86:43-46.
7. Franklin S, Faxon D. Pharmacological prevention of restenosis after coronary angioplasty: Review of randomized clinical trials. Coronary Artery Dis 1993;4:232-242.
8. Leclercq F, Grolleau R. Les mécanismes de la resténose après angioplastie coronaire. Arch Mal Coeur 1996;89:359-365.
9. Lodish H, Baltimore D, Berk A, et al. Oncogenes and their proteins: Classification and characteristics. In Molecular Cell Biology (third ed.), New York: W.H. Freeman, 1995, pp 1258-1269.
10. Levy R. Les inhibiteurs de la farnésyl-transférase (anti-ras): Une nouvelle classe d'anti-cancéreux. Presse Med 1995;24: 725-729.
11. Hélène C, Saison-Behmoaras E. La stratégie antisens: Nouvelles approches thérapeutiques. Médecine/Sciences 1994; 10:253-273.
12. Chemla E, Julia P, Nierat J, et al. Action des oligonucléotides antisens sur l'hyperplasie myo-intimale dans un modèle de traumatisme d'aortes abdominales de rat. Arch Mal Coeur 1995;88:381-389.
13. Simons M, Edelmaner ER, Dekeyser JL, et al. Antisense c-myb oligonucleotides inhibit intimal arterial smooth muscle cell accumulation in vivo. Nature 1992;359:67-70.
14. Simons M, Rosenberg RD. Antisense nonmuscle myosin heavy chain and c-myb oligonucleotides suppress smooth muscle cell proliferation in vitro. Circ Res 1992;70:835-843.
15. Shi Y, Hutchinson H, Hall D, Zalewski A. Downregulation of c-myc expression by antisense oligonucleotides inhibits proliferation of human smooth muscle cells. Circulation 1993; 88:1190-1195.
16. Bennet MR, Anglin S, McEwan JR, et al. Inhibition of vascular smooth muscle cell proliferation in vitro and in vivo by c-myc antisense oligodeoxynucleotides. J Clin Invest 1994; 93:820-828.
17. Stemerman M, Weinstein R, Rowe J, et al. Vascular smooth muscle growth kinetics in vivo in aged rats. Proc Natl Acad Sci USA 1982;79:3863-3866.
18. Bauters C, Marotte F, Hamon M, et al. Accumulation of fetal fibronectine after balloon denudation of rabbit arteries. Circulation 1995;92:904-911.
19. Strauss B, Chisholm R, Keeley F, et al. Extracellular matrix remodeling alter balloon angioplasty injury in a model of restenosis. Circ Res 1994;75:650-658.
20. Azrin M, Ling F, Chen Q, et al. Preparation, characterization, and evaluation of a monoclonal antibody against the rabbit platelet glycoprotein IIb/IIIa in an experimental angioplasty model. Circ Res 1994;75:268-277.
21. Indolfi C, Esposito G, Lorenzo ED, et al. Smooth muscle cell proliferation is proportional to the degree of balloon injury in a rat model of angioplasty. Circulation 1995;92:1230-1235.
22. Shi Y, Fard A, Galco A, et al. Transcatheter delivery of c-myc antisense oligomers reduces neointimal formation in a porcine model of coronary artery balloon injury. Circulation 1994;90:944-951.
23. Stein C, Krieg A. Problems in interpretation of data derived from in vitro and in vivo use of antisense oligodeoxynucleotides. Antisense Res Dev 1994;4:67-69.
24. Castier Y, Chemla E, Chardigny C, et al. Effets sur la proliferation myointimale d'un oligonucleotide antisens dirigé contre le c-myb: Spécificité d'action et conséquences sur la vasoréactivité. Arch Mal Coeur 1996;89:889-896.
25. Burgess T, Fisher E, Ross S, et al. The antiproliferative activity of c-myb and antisense oligonucleotides in smooth muscle cells is caused by a nonantisense mechanism. Proc Natl Acad Sci USA 1994;2:4051-4055.
26. Villa A, Guzman L, Poptic E, et al. Effects of antisense c-myb oligonucleotides on vascular smooth muscle cell proliferation and response to vessel wall injury. Cir Res 1995;76:505-513.
27. Laughlan G, Murchie A, Norman D, et al. The high-resolution crystal of a parallel-stranded guanine teraplex. Science 1994;265:520-524.
28. Morishita R, Gibbons G, Kaneda Y, et al. Pharmacokinetics of antisense oligodeoxyribonucleotides (cyclin B1 and CDC 2 kinase) in the vessel wall in vivo: Enhanced therapeutic utility for restenosis by HVJ-liposome delivery. Gene 1994; 149:13-19.
29. Travis J. Novel anticancer agents move closer to reality. Science 1993;260:1877-1878.
30. Barhacid M. Ras gene. Annu Rev Bioch 1987;56:779-860.
31. Bos J. Ras oncogenes in human cancer: a review. Cancer Res 1989;44:682-689.
32. Gunzburg JD. Les petites protéines G. Médecine Science 1992;8:322-323.
33. Willumsen B, Christensen A, Hubbert N, et al. The p21 ras C-terminus is required for transformation and membrane association. Nature 1984;310:583-586.
34. Clagett G, Robinowitz M, Youkey J. Morphogenesis and clinopathologic characteristics of recurrent carotid disease. J Vasc Surg 1986;3:10-22.
35. Connall T, Wilson S. Vascular access for hemodialysis. In Vascular Surgery (fourth ed.), Philadelphia: W.B. Saunders, 1995, Vol. 1, pp 1233-1244.