-
1
-
-
0028800375
-
Dexamethasone induction of taxol metabolism in the rat
-
Anderson CD, Wang J, Kumar GN, McMillan JM, Walle UK and Walle T (1995) Dexamethasone induction of taxol metabolism in the rat. Drug Metab Dispos 23:1286-1290.
-
(1995)
Drug Metab Dispos
, vol.23
, pp. 1286-1290
-
-
Anderson, C.D.1
Wang, J.2
Kumar, G.N.3
McMillan, J.M.4
Walle, U.K.5
Walle, T.6
-
2
-
-
0030011666
-
A case report of paclitaxel administered to a patient with platinum-refractory ovarian cancer on long-term hemodialysis
-
Balat O, Kudelka AP, Edwards CL, Verschraegen C, Mante R and Kavanagh JJ (1996) A case report of paclitaxel administered to a patient with platinum-refractory ovarian cancer on long-term hemodialysis. Eur J Gynaecol Oncol 17:232-233.
-
(1996)
Eur J Gynaecol Oncol
, vol.17
, pp. 232-233
-
-
Balat, O.1
Kudelka, A.P.2
Edwards, C.L.3
Verschraegen, C.4
Mante, R.5
Kavanagh, J.J.6
-
3
-
-
0032144286
-
Linearized colorimetric assay for Cremophor EL: Application to pharmacokinetics afler 1-hour paclitaxel infusions
-
Brouwer E, Verweij J, Hauns B, Loos WJ, Nooter K, Mross K, Stoter G and Sparreboom A (1998) Linearized colorimetric assay for Cremophor EL: Application to pharmacokinetics afler 1-hour paclitaxel infusions. Anal Biochem 261:198-202.
-
(1998)
Anal Biochem
, vol.261
, pp. 198-202
-
-
Brouwer, E.1
Verweij, J.2
Hauns, B.3
Loos, W.J.4
Nooter, K.5
Mross, K.6
Stoter, G.7
Sparreboom, A.8
-
4
-
-
4243910847
-
Paclitaxel pharmacokinetic/pharmacodynamic relationships in patients with renal dysfunction
-
Conley BA, Zaharski D, Kearns CM, Rosen DM, Van Echo DA and Egorin MJ (1997) Paclitaxel pharmacokinetic/pharmacodynamic relationships in patients with renal dysfunction (Abstract). Proc Am Soc Clin Oncol 16:233a.
-
(1997)
Proc Am Soc Clin Oncol
, vol.16
-
-
Conley, B.A.1
Zaharski, D.2
Kearns, C.M.3
Rosen, D.M.4
Van Echo, D.A.5
Egorin, M.J.6
-
5
-
-
0027954464
-
Taxol metabolism by human liver microsomes: Identification of cytochrome P450 involved in its biotransformation
-
Cresteil T, Monsarrat B, Alvinerie P, Treluyer M, Viera I and Wright M (1994) Taxol metabolism by human liver microsomes: Identification of cytochrome P450 involved in its biotransformation. Cancer Res 54:386-392.
-
(1994)
Cancer Res
, vol.54
, pp. 386-392
-
-
Cresteil, T.1
Monsarrat, B.2
Alvinerie, P.3
Treluyer, M.4
Viera, I.5
Wright, M.6
-
6
-
-
0013559271
-
Pharmacokinetic assessment of paclitaxel in an ovarian cancer patient on hemodialysis
-
Fazeny B, Olsen SJ, Willey T, Stewart MB, Dittrich E, Huber H and Dittrich C (1995) Pharmacokinetic assessment of paclitaxel in an ovarian cancer patient on hemodialysis (Abstract). Proc Am Soc Clin Oncol 14:173.
-
(1995)
Proc Am Soc Clin Oncol
, vol.14
, pp. 173
-
-
Fazeny, B.1
Olsen, S.J.2
Willey, T.3
Stewart, M.B.4
Dittrich, E.5
Huber, H.6
Dittrich, C.7
-
7
-
-
0028894301
-
Nonlinear pharmacokinetics and metabolism of paclitaxel and its pharmacokinetic/ pharmacodynamic relationships in humans
-
Gianni L, Kearns CM, Giani AN, Capri G, Vigano L, Locatelli A, Bonadonna G and Egorin MJ (1995) Nonlinear pharmacokinetics and metabolism of paclitaxel and its pharmacokinetic/ pharmacodynamic relationships in humans. J Clin Oncol 13:180-190.
-
(1995)
J Clin Oncol
, vol.13
, pp. 180-190
-
-
Gianni, L.1
Kearns, C.M.2
Giani, A.N.3
Capri, G.4
Vigano, L.5
Locatelli, A.6
Bonadonna, G.7
Egorin, M.J.8
-
8
-
-
0028345782
-
Isolation, structural determination, and biological activity of 6α-hydroxytaxol, the principal human metabolite of taxol
-
Harris JW, Katki A, Anderson LW, Chmurny GN, Paukstelis JV and Collins JM (1994a) Isolation, structural determination, and biological activity of 6α-hydroxytaxol, the principal human metabolite of taxol. J Med Chem 37:706-709.
-
(1994)
J Med Chem
, vol.37
, pp. 706-709
-
-
Harris, J.W.1
Katki, A.2
Anderson, L.W.3
Chmurny, G.N.4
Paukstelis, J.V.5
Collins, J.M.6
-
9
-
-
0027957132
-
Metabolism of taxol by hepatic microsomes and liver slices: Participation of cytochrome P450 3A4 and an unknown P450 enzyme
-
Harris JW, Rahman A, Kim BR, Guengerich FP and Collins JM (1994b) Metabolism of taxol by hepatic microsomes and liver slices: Participation of cytochrome P450 3A4 and an unknown P450 enzyme. Cancer Res 54:4026-4035.
-
(1994)
Cancer Res
, vol.54
, pp. 4026-4035
-
-
Harris, J.W.1
Rahman, A.2
Kim, B.R.3
Guengerich, F.P.4
Collins, J.M.5
-
10
-
-
0028201724
-
Cytochrome P450 mediated human liver microsomal taxol 6A hydroxylation
-
Kumar GN, Walle UK and Walle T (1994) Cytochrome P450 mediated human liver microsomal taxol 6A hydroxylation. J Pharmacol Exp Ther 268:1160-1165.
-
(1994)
J Pharmacol Exp Ther
, vol.268
, pp. 1160-1165
-
-
Kumar, G.N.1
Walle, U.K.2
Walle, T.3
-
11
-
-
0024327106
-
Taxol: A unique antineoplastic agent with significant activity in advanced ovarian epithelial neoplasms
-
McGuire WP, Rowinsky EK, Rosenshein NB, Grumbine FC, Ettinger DS, Armstrong DK and Donehower RC (1989) Taxol: A unique antineoplastic agent with significant activity in advanced ovarian epithelial neoplasms. Ann Intern Med 111:273-279.
-
(1989)
Ann Intern Med
, vol.111
, pp. 273-279
-
-
McGuire, W.P.1
Rowinsky, E.K.2
Rosenshein, N.B.3
Grumbine, F.C.4
Ettinger, D.S.5
Armstrong, D.K.6
Donehower, R.C.7
-
12
-
-
0027864070
-
Hepatic metabolism and biliary excretion of taxol in rats and human
-
Monsarrat B, Alvinerie P, Wright M, Dubois J, Guéritte-Voegelein F, Guénard D, Donehower RC and Rowinsky EK (1993) Hepatic metabolism and biliary excretion of taxol in rats and human. J Natl Cancer Inst Monogr 15:39-46.
-
(1993)
J Natl Cancer Inst Monogr
, vol.15
, pp. 39-46
-
-
Monsarrat, B.1
Alvinerie, P.2
Wright, M.3
Dubois, J.4
Guéritte-Voegelein, F.5
Guénard, D.6
Donehower, R.C.7
Rowinsky, E.K.8
-
13
-
-
0031892907
-
Modification of paclitaxel metabolism in a cancer patient by induction of cytochrome P450 3A4
-
Monsarrat B, Chatelut E, Royer I, Alvinerie P, Dubois J, Dezeuse A, Roche H, Cros S, Wright M and Canal P (1998) Modification of paclitaxel metabolism in a cancer patient by induction of cytochrome P450 3A4. Drug Metab Dispos 26:229-233.
-
(1998)
Drug Metab Dispos
, vol.26
, pp. 229-233
-
-
Monsarrat, B.1
Chatelut, E.2
Royer, I.3
Alvinerie, P.4
Dubois, J.5
Dezeuse, A.6
Roche, H.7
Cros, S.8
Wright, M.9
Canal, P.10
-
14
-
-
0031620829
-
Chemotherapy of ovarian cancer
-
Ozols RF (1998) Chemotherapy of ovarian cancer. Cancer Treat Res 95:219-234.
-
(1998)
Cancer Treat Res
, vol.95
, pp. 219-234
-
-
Ozols, R.F.1
-
15
-
-
0028036727
-
Selective biotransformation of taxol to 6α-hydroxylaxol by human cytochrome P450 2C8
-
Rahman A, Korzekwa KR, Grogan J, Gonzalez FJ and Harris JW (1994) Selective biotransformation of taxol to 6α-hydroxylaxol by human cytochrome P450 2C8. Cancer Res 54:5543-5546.
-
(1994)
Cancer Res
, vol.54
, pp. 5543-5546
-
-
Rahman, A.1
Korzekwa, K.R.2
Grogan, J.3
Gonzalez, F.J.4
Harris, J.W.5
-
16
-
-
0028288626
-
Taxol and taxotere in bladder cancer: In vitro activity and urine stability
-
Rangel C, Niell H, Miller A and Cox C (1994) Taxol and taxotere in bladder cancer: In vitro activity and urine stability. Cancer Chemother Pharmacol 33:460-464.
-
(1994)
Cancer Chemother Pharmacol
, vol.33
, pp. 460-464
-
-
Rangel, C.1
Niell, H.2
Miller, A.3
Cox, C.4
-
17
-
-
0013625935
-
Pharmacology and metabolism
-
McGuire WP and Rowinsky EK eds, Marcel Dekker, New York
-
Rowinsky EK (1995) Pharmacology and metabolism, in Paclitaxel in Cancer Treatment (McGuire WP and Rowinsky EK eds) pp 91-120, Marcel Dekker, New York.
-
(1995)
Paclitaxel in Cancer Treatment
, pp. 91-120
-
-
Rowinsky, E.K.1
-
18
-
-
0029173748
-
Paclitaxel metabolites in human plasma and urine: Identification of 6α-hydroxytaxol, 7-epitaxol and taxol hydrolysis products using liquid chromatography/atmospheric-pressure chemical ionization mass spectrometry
-
Royer I, Alvinerie P, Armand JP, Ho LK, Wright M and Monsarrat B (1995) Paclitaxel metabolites in human plasma and urine: Identification of 6α-hydroxytaxol, 7-epitaxol and taxol hydrolysis products using liquid chromatography/atmospheric-pressure chemical ionization mass spectrometry. Rapid Commun Mass Spectrom 9:495-502.
-
(1995)
Rapid Commun Mass Spectrom
, vol.9
, pp. 495-502
-
-
Royer, I.1
Alvinerie, P.2
Armand, J.P.3
Ho, L.K.4
Wright, M.5
Monsarrat, B.6
-
21
-
-
0032559438
-
Determination of paclitaxel in human plasma using single solvent extraction before isocratic reversed-phase high-performance liquid chromatography with ultraviolet detection
-
Sparreboom A, De Bruijn P, Nooter K, Loos WJ, Stoter G and Verweij J (1998a) Determination of paclitaxel in human plasma using single solvent extraction before isocratic reversed-phase high-performance liquid chromatography with ultraviolet detection. J Chrontatogr Biomed Sci Appl 705:159-164.
-
(1998)
J Chrontatogr Biomed Sci Appl
, vol.705
, pp. 159-164
-
-
Sparreboom, A.1
De Bruijn, P.2
Nooter, K.3
Loos, W.J.4
Stoter, G.5
Verweij, J.6
-
22
-
-
0029052241
-
Isolation, purification and biological activity of mono-and dihydroxylated paclitaxel metabolites from human feces
-
Sparreboom A, Huizing MT, Boessen JJB, Nooijen WJ, Van Tellingen O and Beijnen JH (1995) Isolation, purification and biological activity of mono-and dihydroxylated paclitaxel metabolites from human feces. Cancer Chemother Pharmacol 36:299-304.
-
(1995)
Cancer Chemother Pharmacol
, vol.36
, pp. 299-304
-
-
Sparreboom, A.1
Huizing, M.T.2
Boessen, J.J.B.3
Nooijen, W.J.4
Van Tellingen, O.5
Beijnen, J.H.6
-
23
-
-
0032518340
-
Quantitation of Cremophor EL in human plasma samples using a colorimetric dye-binding microassay
-
Sparreboom A, Loos WJ, Verweij J, De Vos AI, Van der Burg MEL, Stoter O and Nooter K (1998b) Quantitation of Cremophor EL in human plasma samples using a colorimetric dye-binding microassay. Anal Biochem 255:171-175.
-
(1998)
Anal Biochem
, vol.255
, pp. 171-175
-
-
Sparreboom, A.1
Loos, W.J.2
Verweij, J.3
De Vos, A.I.4
Van Der Burg, M.E.L.5
Stoter, O.6
Nooter, K.7
-
24
-
-
12644278301
-
Limited oral bioavailabilily and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine
-
Sparreboom A, Van Asperen J, Mayer U, Schinkel AH, Smit JW, Meijer DKF, Borst P, Nooijen WJ, Beijnen JH and Van Tellingen O (1997) Limited oral bioavailabilily and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine. Proc Natl Acad Sci USA 94:2031-2035.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 2031-2035
-
-
Sparreboom, A.1
Van Asperen, J.2
Mayer, U.3
Schinkel, A.H.4
Smit, J.W.5
Meijer, D.K.F.6
Borst, P.7
Nooijen, W.J.8
Beijnen, J.H.9
Van Tellingen, O.10
-
25
-
-
0029921281
-
Nonlinear pharmacokinetics of paclitaxel in mice results from the pharmaceutical vehicle Cremophor EL
-
Sparreboom A, Van Tellingen O, Nooijen WJ and Beijnen JH (1996) Nonlinear pharmacokinetics of paclitaxel in mice results from the pharmaceutical vehicle Cremophor EL. Cancer Res 56:2112-2115.
-
(1996)
Cancer Res
, vol.56
, pp. 2112-2115
-
-
Sparreboom, A.1
Van Tellingen, O.2
Nooijen, W.J.3
Beijnen, J.H.4
-
26
-
-
0033118955
-
Cremophor EL-mediated alteration of paclitaxel distribution in human blood: Clinical pharmacokinetic implications
-
Sparreboom A, Van Zuylen L, Brouwer E, Loos WJ, De Bruijn P, Gelderblom H, Pillay M, Nooler K, Stoter G and Verweij J (1999) Cremophor EL-mediated alteration of paclitaxel distribution in human blood: Clinical pharmacokinetic implications. Cancer Res 59:1454-1457.
-
(1999)
Cancer Res
, vol.59
, pp. 1454-1457
-
-
Sparreboom, A.1
Van Zuylen, L.2
Brouwer, E.3
Loos, W.J.4
De Bruijn, P.5
Gelderblom, H.6
Pillay, M.7
Nooler, K.8
Stoter, G.9
Verweij, J.10
-
27
-
-
0031872770
-
Disposition of Cremophor EL in humans limits the potential for modulation of the multidrug resistance phenotype in vivo
-
Sparreboom A, Verweij J, Van der Burg MEL, Loos WJ, Brouwer E, Vigano L, Locatelli A, De Vos AI, Nooter K, Stoter G and Gianni L (1998c) Disposition of Cremophor EL in humans limits the potential for modulation of the multidrug resistance phenotype in vivo. Clin Cancer Res 4:1937-1942.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 1937-1942
-
-
Sparreboom, A.1
Verweij, J.2
Van Der Burg, M.E.L.3
Loos, W.J.4
Brouwer, E.5
Vigano, L.6
Locatelli, A.7
De Vos, A.I.8
Nooter, K.9
Stoter, G.10
Gianni, L.11
-
28
-
-
0031832839
-
Phase 1 and pharmacokinetic trial of paclitaxel in patients with hepatic dysfunction: Cancer and leukemia group B9264
-
Venook AP, Egorin MJ, Rosner GL, Brown TD, Jahan TM, Batist G, Hohl R, Budman D, Ratain MJ, Kearns CM and Schilsky RL (1998) Phase 1 and pharmacokinetic trial of paclitaxel in patients with hepatic dysfunction: Cancer and leukemia group B9264. J Clin Oncol 16:1811-1819.
-
(1998)
J Clin Oncol
, vol.16
, pp. 1811-1819
-
-
Venook, A.P.1
Egorin, M.J.2
Rosner, G.L.3
Brown, T.D.4
Jahan, T.M.5
Batist, G.6
Hohl, R.7
Budman, D.8
Ratain, M.J.9
Kearns, C.M.10
Schilsky, R.L.11
-
30
-
-
0031920377
-
Paclitaxel. An update of its use in the treatment of metastatic breast cancer and ovarian and other gynaecological cancers
-
Wiseman LR and Spencer CM (1998) Paclitaxel. An update of its use in the treatment of metastatic breast cancer and ovarian and other gynaecological cancers. Drug Aging 12:305-334.
-
(1998)
Drug Aging
, vol.12
, pp. 305-334
-
-
Wiseman, L.R.1
Spencer, C.M.2
-
31
-
-
0032943211
-
Pharmacokinetics of paclitaxel in an anephric patient
-
Woo MH, Gregornik D, Shearer PD, Meyer WH and Relling MV (1999) Pharmacokinetics of paclitaxel in an anephric patient. Cancer Chemother Pharmacol 43:92-96.
-
(1999)
Cancer Chemother Pharmacol
, vol.43
, pp. 92-96
-
-
Woo, M.H.1
Gregornik, D.2
Shearer, P.D.3
Meyer, W.H.4
Relling, M.V.5
|