Molecular medicine in the 21st century

Internal Medicine Journal

Volumn 31, Issue 1, 2001, Pages 53-59

  Semsarian, Christopher ^a,c   Seidman, C E ^a,b  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

DNA; Genetics; Human Genome Project; Medicine; Molecular

Indexed keywords

CARDIOMYOPATHY; GENE MUTATION; GENETIC DISORDER; GENOTYPE; HUMAN; HYPERTROPHIC CARDIOMYOPATHY; MOLECULAR GENETICS; PRIORITY JOURNAL; REVIEW; SCREENING TEST;

CARDIOMYOPATHY, HYPERTROPHIC, FAMILIAL; FORECASTING; GENETICS, MEDICAL; HISTORY, 20TH CENTURY; HISTORY, 21ST CENTURY; HUMAN GENOME PROJECT; HUMANS; MUTATION;

EID: 0035001849     PISSN: 14440903     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1445-5994.2001.00001.x     Document Type: Review

References (46)

1. World leaders heap praise on human genome landmark
2. Gene mutations that cause familial hypertrophic cardiomyopathy
3. Molecular genetic studies of familial hypertrophic cardiomyopathy
4. Congenital heart disease caused by mutations in the transcription factor Nkx-2.5
5. Genetic approaches to cardiovascular disease: Supravalvular aortic stenosis, Williams syndrome, and long QT syndrome
6. Mutations in the human gene for fibrillin-1 in the Marfan syndrome and related disorders
7. Gene therapy for angiogenesis, restenosis and related diseases
8. Gene therapy for coronary disease
9. Angiogenesis: A breakthrough technology in cardiovascular medicine
10. Gene therapy for restenosis
11. Asymmetrical hypertrophy of the heart in young adults
12. Cardiovascular diseases due to genetic abnormalities
13. The management of hypertrophic cardiomyopathy
14. Hypertrophic cardiomyopathy: A common cause of sudden death in the young competitive athlete
15. Causes of sudden death in competitive athletes
16. Sudden death in young competitive athletes - Clinical, demographic and pathological profiles
17. Sudden cardiac death in familial hypertrophic cardiomyopathy
18. Hypertrophic cardiomyopathy
19. Prevalence of hypertrophic cardiomyopathy in a general population of young adults: Echocardiographic analysis of 4111 subjects in the CARDIA Study
20. Familial hypertrophic cardiomyopathy with Wolff-Parkinson-White syndrome maps to a locus on chromosome 7q3
21. Hypertrophic cardiomyopathy: Interrelations of clinical manifestations, pathophysiology and therapy
22. Expression and functional assessment of a truncated cardiac troponin T that causes hypertrophic cardiomyopathy: Evidence for a dominant negative action
23. The standard electrocardiogram as a screening test for hypertrophic cardiomyopathy
24. Characteristics and prognostic implications of myosin missense mutations in familial hypertrophic cardiomyopathy
25. Prognostic implications of novel β-cardiac myosin heavy chain gene mutations that cause familial hypertrophic cardiomyopathy
26. Mutations in the gene for cardiac myosin-binding protein C and late-onset familial hypertrophic cardiomyopathy
27. Difficulties in the diagnosis of apical hypertrophic cardiomyopathy
28. Role of alcohol septal ablation in treatment of obstructive hypertrophic cardiomyopathy
29. Efficacy of implantable cardioverter-defibrillators for the prevention of sudden death in patients with hypertrophic cardiomyopathy
30. A calcineurin-dependent transcriptional pathway for cardiac hypertrophy
31. Prevention of cardiac hypertrophy in mice by calcineurin inhibition
32. 2+ dependent calcineurin signalling pathway
33. Cyclosporin A and minoxidil exacerbate cardiac hypertrophy in hypertrophic cardiomyopathy via a calcium-mediated pathway
34. Left ventricular hypertrophy and morphology in familial hypertrophic cardiomyopathy associated with mutations of the beta-myosin heavy chain gene
35. Sudden cardiac death in familial hypertrophic cardiomyopathy: Are benign mutations really benign?
36. Mutations in the gene encoding lamin A/C cause autosomal dominant Emery-Dreifuss muscular dystrophy
37. Recent insights into the molecular pathogenesis of Huntington disease
38. Genetic disorders affecting proteins of iron metabolism: Clinical implications
39. Familial myeloproliferative disease
40. Angiotensin-converting enzyme polymorphism in hypertrophic cardiomyopathy and sudden death
41. Angiotensin-I converting enzyme genotypes and left ventricular hypertrophy in patients with hypertrophic cardiomyopathy
42. Molecular structure of nucleic acids: A structure for deoxyribose nucleic acid
43. Finally, the Book of Life and instructions for navigating it
44. And the gene number is ...?
45. The clinician-scientist in the 21st century
46. Economic rationalism in health and education; impact of the academic physician