Meconium induces expression of inducible NO synthase and activation of NF-κB in rat alveolar macrophages

Pediatric Research

Volumn 49, Issue 6, 2001, Pages 820-825

  Li, Ying Hua ^a   Yan, Zhong Qun ^a   Brauner, Annelie ^a   Tullus, Kjell ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BUDESONIDE; COMPLEMENTARY DNA; CYCLOHEXIMIDE; DEXAMETHASONE; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DOWN REGULATION; ENZYME ACTIVATION; GENE EXPRESSION; INFLAMMATORY CELL; LUNG ALVEOLUS MACROPHAGE; MECONIUM; MECONIUM ASPIRATION; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0034993750     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/00006450-200106000-00018     Document Type: Article

References (46)

1. Meconium aspiration syndrome: Reflections on a murky subject
2. Macrophage cytotoxicity: Role for L-arginine deiminase and imino nitrogen oxidation to nitrite
3. Nitric oxide: A cytotoxic activated macrophage effector molecule
4. Nitric oxide. I. Physiological chemistry of nitric oxide and its metabolites: Implications in inflammation
5. Cloning and characterization of inducible nitric oxide synthase from mouse macrophages
6. Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing: Molecular basis for the synergy between interferon-gamma and lipopolysaccharide
7. Role of inducible nitric oxide synthase in endotoxin-induced acute lung injury
8. Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide
9. Inhaled nitric oxide decreases hyperoxia-induced surfactant abnormality in preterm rabbits
10. Nuclear factor kappa B: Important transcription factor and therapeutic target
11. Different induction mechanisms of mRNA for inducible nitric oxide synthase in rat smooth muscle cells in culture and in aortic strips
12. Induced expression of mRNA for IL-5, IL-6, TNF-alpha, MIP-2 and IFN-gamma in immunologically activated rat peritoneal mast cells: Inhibition by dexamethasone and cyclosporin A
13. Augmented expression of inducible NO synthase in vascular smooth muscle cells during aging is associated with enhanced NF-kappaB activation
14. Meconium-induced lung injury mediated by activation of alveolar macrophages
15. Meconium aspiration syndrome: Physiological and inflammatory changes in a newborn piglet model
16. Meconium increases surfactant secretion in isolated rat alveolar type II cells
17. Effect of interleukin 8 in meconium on in-vitro neutrophil chemotaxis
18. Inhibition of neutrophil oxidative burst and phagocytosis by meconium
19. Differential expression of interleukin-1 beta and interleukin-6 in human fetal serum and meconium-stained amniotic fluid
20. Meconium aspiration induces a concentration-dependent pulmonary hypertensive response in newborn piglets
21. Intratracheal suctioning, systemic infection, and the meconium aspiration syndrome
22. Resuscitation of the newborn
23. The role of pulmonary vascular endothelium in perinatal pulmonary circulatory regulation
24. The pulmonary vasculature in meconium aspiration
25. Persistent pulmonary hypertension in the neonate: Diagnosis and management
26. Inducible nitric oxide synthase and nitric oxide production in Leishmania infantum-infected human macrophages stimulated with interferon-gamma and bacterial lipopolysaccharide
27. Nitric oxide and septic shock
28. Nitric oxide production in critically ill patients
29. Diminished inducible nitric oxide synthase expression in fulminant early-onset neonatal pneumonia
30. Nitric oxide production and nitric oxide synthase type 2 expression by human mononuclear phagocytes: A review
31. Pneumococci stimulate the production of the inducible nitric oxide synthase and nitric oxide by murine macrophages
32. Inflammatory responses induced by the filarial nematode Brugia malayi are mediated by lipopolysaccharide-like activity from endosymbiotic Wolbachia bacteria
33. Specific inhibitors of p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways block inducible nitric oxide synthase and tumor necrosis factor accumulation in murine macrophages stimulated with lipopolysaccharide and interferon-gamma
34. Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide
35. Generation of nitric oxide and induction of major histocompatibility complex class II antigen in macrophages from mice lacking the interferon gamma receptor
36. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
37. Negative inotropic effects of cytokines on the heart mediated by nitric oxide
38. Clinical approach to inhaled nitric oxide therapy in the newborn with hypoxemia
39. Inhaled nitric oxide in full-term and nearly full-term infants with hypoxic respiratory failure
40. Randomized, multicenter trial of inhaled nitric oxide and high-frequency oscillatory ventilation in severe, persistent pulmonary hypertension of the newborn
41. Nitric oxide inhalation inhibits pulmonary apoptosis but not inflammatory injury in porcine meconium aspiration
42. Use of nitric oxide in meconium aspiration syndrome: Lack of response
43. New insights into the role of nuclear factor-kappaB, a ubiquitous transcription factor in the initiation of diseases
44. Meconium aspiration syndrome: Current concepts and management
45. The effects of cyclosporine and dexamethasone on an alveolar macrophage cell line (NR8383)
46. Efficacy and safety of inhaled corticosteroids in asthma: Report of a workshop held in Eze, France, October 1992