Gamma scintigraphy of the biodistribution of 123I-labelled N-(2-hydroxypropyl)methacrylamide copolymer-doxorubicin conjugates in mice with transplanted melanoma and mammary carcinoma

Journal of Drug Targeting

Volumn 3, Issue 5, 1996, Pages 375-383

  Pimm, Malcolm V ^a   Perkins, Alan C ^b   Strohalm, Jiri ^c   Ulbrich, Karel ^c   Duncan, Ruth ^d,e  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST   (United Kingdom)

^c INSTITUTE OF MACROMOLECULAR CHEMISTRY   (Czech Republic)

^d KEELE UNIVERSITY   (United Kingdom)

^e UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Drug targeting; Gamma camera imaging; N (hydroxypropyl)methacrylamide copolymers; Polymeric drug carriers

Indexed keywords

ACRYLAMIDE DERIVATIVE; COPOLYMER; DOXORUBICIN; DRUG CARRIER; IODINE 123; N (2 HYDROXYPROPYL)METHACRYLAMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CARCINOMA; CANCER TRANSPLANTATION; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG LIVER LEVEL; DRUG STRUCTURE; DRUG TARGETING; DRUG TUMOR LEVEL; FEMALE; GAMMA SCINTIGRAPHY; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; ISOTOPE LABELING; KIDNEY; MELANOMA; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN; URINARY EXCRETION;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CARCINOMA; DOXORUBICIN; DRUG DELIVERY SYSTEMS; FEMALE; GAMMA RAYS; INJECTIONS, INTRAPERITONEAL; INJECTIONS, INTRAVENOUS; IODINE RADIOISOTOPES; ISOTOPE LABELING; KIDNEY; MAMMARY NEOPLASMS, EXPERIMENTAL; MELANOMA, EXPERIMENTAL; METHACRYLATES; MICE; MICE, INBRED C57BL; MOLECULAR WEIGHT; NEOPLASM TRANSPLANTATION; RADIONUCLIDE IMAGING; TISSUE DISTRIBUTION;

EID: 0030029223     PISSN: 1061186X     EISSN: None     Source Type: Journal    
DOI: 10.3109/10611869608996828     Document Type: Article

References (22)

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