Expression of CYP2A6 in tumor cells augments cellular sensitivity to Tegafur

Japanese Journal of Cancer Research

Volumn 92, Issue 5, 2001, Pages 524-528

  Murayama, Norie ^a   Sai, Kimie ^a   Nakajima, Yukiko ^a   Kaniwa, Naoko ^a   Ozawa, Shogo ^a   Ohno, Yasuo ^a   Sawada, Juna Ichi ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

5 FU; CYP2A6; Prodrug; Tegafur; Tumor cells

Indexed keywords

4 HYDROXYCOUMARIN; COMPLEMENTARY DNA; COUMARIN; CYTOCHROME P450 2A6; DRUG METABOLITE; FLUOROURACIL; PRODRUG; TEGAFUR;

ARTICLE; CANCER CELL CULTURE; CATALYSIS; CELL TYPE; COLON CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG HYDROXYLATION; DRUG METABOLISM; GENE CONSTRUCT; GENE EXPRESSION; GENETIC TRANSFECTION; GROWTH INHIBITION; PRIORITY JOURNAL; SENSITIZATION; STATISTICAL ANALYSIS;

ANTIMETABOLITES, ANTINEOPLASTIC; ARYL HYDROCARBON HYDROXYLASES; CELL DIVISION; COLONIC NEOPLASMS; COUMARINS; CYTOCHROME P-450 ENZYME SYSTEM; FLUOROURACIL; GENE EXPRESSION; HUMANS; HYDROXYLATION; MICROSOMES; MIXED FUNCTION OXYGENASES; TEGAFUR; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0034988191     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2001.tb01125.x     Document Type: Article

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