Ancestral residues stabilizing 3-isopropylmalate dehydrogenase of an extreme thermophile: Experimental evidence supporting the thermophilic common ancestor hypothesis

Journal of Biochemistry

Volumn 129, Issue 5, 2001, Pages 777-782

  Miyazaki, Junichi ^a   Nakaya, Shuichi ^a   Suzuki, Toshiharu ^a   Tamakoshi, Masatada ^a   Oshima, Tairo ^a   Yamagishi, Akihiko ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

3 Isopropylmalate dehydrogenase; Archaeon (archaebacterium); Common ancestor; Protein stability; Sulfolobus

Indexed keywords

3 ISOPROPYLMALATE DEHYDROGENASE; AMINO ACID; MUTANT PROTEIN;

ARTICLE; BACTERIUM MUTANT; DATA BASE; ENZYME STABILITY; ENZYME STRUCTURE; HYPOTHESIS; NONHUMAN; STRUCTURE ANALYSIS; SULFOLOBUS; THERMOPHILIC BACTERIUM; THERMOSTABILITY;

CIRCULAR DICHROISM; ENZYME STABILITY; ESCHERICHIA COLI; HEAT; HYDRO-LYASES; ISOCITRATE DEHYDROGENASE; MODELS, MOLECULAR; MUTAGENESIS; PROTEIN DENATURATION; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; SULFOLOBUS; THERMUS;

ARCHAEA; BACTERIA (MICROORGANISMS); SULFOLOBUS; SULFOLOBUS SP.;

EID: 0034986432     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a002919     Document Type: Article

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