Prologue: EDHF - What is it?

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 280, Issue 6 49-6, 2001, Pages

  Campbell, W B ^a   Harder, D R ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; BRADYKININ; CHARYBDOTOXIN; ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; EPOXYICOSATRIENOIC ACID; MICONAZOLE; NITRIC OXIDE SYNTHASE; POTASSIUM; POTASSIUM CHANNEL BLOCKING AGENT; PROSTAGLANDIN SYNTHASE;

BLOOD VESSEL TONE; EDITORIAL; ENDOTHELIUM; HYPERPOLARIZATION; PRIORITY JOURNAL; VASODILATATION;

EID: 0034979364     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.2001.280.6.h2413     Document Type: Editorial

References (45)

1. 2-arachidonic acid signaling cascade in coronary artery smooth muscle
2. Ca channel activity
3. Nitric oxide attenuates the release of endothelium-derived hyperpolarizing factor
4. Molecular characterization and localization of the NAD(P)H oxidase components gp91-phox and p22-phox in endothelial cells
5. Hydrogen peroxide: An endogenous smooth muscle cell hyperpolarizing factor
6. Endothelial-dependent relaxant actions of carbachol and substance P in arterial smooth muscle
7. Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors
8. Endothelium-derived hyperpolarizing factors and vascular cytochrome P450 metabolites of arachidonic acid in the regulation of tone
9. Gap junctional communication underpins EDHF-type relaxations evoked by acetylcholine in the rat hepatic artery
10. Acetylcholine released endothelium-derived hyperpolarizing factor and EDRF from rat blood vessels
11. Endothelium-dependent hyperpolarization: Beyond nitric oxide and cyclic GMP
12. + but may be due to spread of current from the endothelium in guinea pig arterioles
13. Inhibitors of the cytochrome P450-mono-oxygenase and endothelium-dependent hyperpolarizations in the guinea-pig isolated carotid artery
14. Properties of smooth muscle hyperpolarization and relaxation to potassium in the rat isolated mesenteric artery
15. Endothelial cell protein kinase G inhibits release of EDHF through a PKG-sensitive cation channel
16. Potassium does not mimic EDHF in rat mesenteric arteries
17. +
18. K is an endothelium-derived hyperpolarizing factor in rat arteries
19. Further investigation of endothelium-derived hyperpolarizing factor (EDHF) in rat hepatic artery: Studies using 1-EBIO and ouabain
20. Effects of cytochrome P450 inhibitors on potassium currents and mechanical activity in rat portal vein
21. Endothelium-dependent hyperpolarization of canine coronary smooth muscle
22. Cytochrome P450 2C is an EDHF synthase in coronary arteries
23. Endothelium-derived hyperpolarizing factor synthase (cytochrome P450 2C9) is a functionally significant source of reactive oxygen species in coronary arteries
24. Pharmacological evaluation of an epoxide as the putative hyperpolarizing factor mediating the nitric oxide-independent vasodilator effect of bradykinin in the rat heart
25. Bioassay of an endothelium-derived hyperpolarizing factor from bovine coronary arteries: Role of a cytochrome P450 metabolite
26. The role of estrogen in modulating EDHF-mediated dilations in the female rat middle cerebral artery
27. Characterization of endothelium-derived hyperpolarizing factor in the human forearm microcirculation
28. Is hydrogen peroxide an EDHF in human radial arteries?
29. Role of cytochrome P-450 enzymes and metabolites of arachidonic acid in the control of vascular tone
30. Formation and action of a P-450 4A metabolite of arachidonic acid in cat cerebral microvessels
31. Characterization of endothelium-derived hyperpolarizing factor as a cytochrome P450-derived arachidonic acid metabolite in mammals
32. EDHF is released to flow in skeletal muscle arterioles of female eNOS-KO mice
33. Evidence against potassium as an endothelium-derived hyperpolarizing factor in rat mesenteric small arteries
34. 20-Hydroxyeicosatetraenoic acid is an endogenous vasoconstrictor of canine renal arcuate arteries
35. Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in mice
36. Heterogenous distribution of endothelium-dependent relaxations resistant to N-nitro-L-arginine in rats
37. In vivo location and mechanism of EDHF-mediated vasodilation in canine coronary microcirculation
38. Endothelium-independent, ouabain-sensitive relaxation of bovine coronary arteries by EETs
39. 2 and EETs in the relaxation of bovine coronary arteries to arachidonic acid
40. Synthesis of hydroxyeicosatetraenoic acids (HETEs) and epoxyeicosatrienoic acids (EETs) by cultured bovine coronary artery endothelial cells
41. Evidence against the involvement of cytochrome P450 metabolites in endothelium-dependent hyperpolarization of the rat main mesenteric artery
42. Super-oxide generation by endothelial nitric oxide synthase: The influence of cofactors
43. Cytochrome P-450 pathway in acetylcholine-induced canine coronary microvascular vasodilation in vivo
44. Gender specific compensation for the lack of nitric oxide in the mediation of flow-indiced arteriolar dilation
45. 2+-activated potassium channels