Epstein-Barr virus nuclear protein 2-induced activation of the EBV-replicative cycle in akata cells: Analysis by tetracycline-regulated expression

Current Topics in Microbiology and Immunology

Volumn 258, Issue , 2001, Pages 35-50

  Fujiwara, S ^a  

^a NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEAR PROTEIN; TETRACYCLINE; TRANSCRIPTION FACTOR; VIRUS NUCLEOPROTEIN;

B LYMPHOCYTE ACTIVATION; CELL IMMORTALIZATION; EPSTEIN BARR VIRUS; GENE EXPRESSION REGULATION; GENE TRANSFER; GENETIC REGULATION; HUMAN; HUMAN CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; REVIEW; VIRUS INDUCTION; VIRUS REPLICATION; VIRUS TRANSFORMATION;

ANIMALIA; DNA VIRUSES; HUMAN HERPESVIRUS 4;

EID: 0034976604     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-642-56515-1_3     Document Type: Review

References (62)

1. Epstein-Barr virus nuclear antigen 2 induces expression of the virus-encoded latent membrane protein
2. Early events in Epstein-Barr virus infection of human B lymphocytes
3. Epstein-Barr virus latent gene expression during the initiation of B cell immortalization
4. Effect of the EBNA2 gene on the surface antigen phenotype of transfected EBV-negative B-lymphoma lines
5. Notch signaling
6. Epstein-Barr virus nuclear protein 2 is a key determinant of lymphocyte transformation
7. Stable transfection of Epstein-Barr virus (EBV) nuclear antigen 2 in lymphoma cells containing the EBV P3HR-1 genome induces expression of B-cell activation molecules CD21 and CD23
8. Activation of latent Epstein-Barr virus via anti-IgG-triggered, second messenger pathways in the Burkitt's lymphoma cell line Akata
9. Expression of the Epstein-Barr virus nuclear protein 2 in rodent cells
10. Epstein-Barr virus-encoded nuclear antigen 2 activates the viral latent membrane protein promoter by modulating the activity of a negative regulatory element
11. Epstein-Barr virus (EBV) nuclear protein 2-induced disruption of EBV latency in the Burkitt's lymphoma cell line Akata: Analysis by tetracycline-regulated expression
12. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
13. The Epstein-Barr virus nuclear antigen 2 transactivator is directed to response elements by the JΚ recombination signal binding protein
14. Characterization of DP103, a novel DEAD box protein that binds to the Epstein-Barr virus nuclear proteins EBNA2 and EBNA3C
15. Genetic analysis of immortalizing Functions of Epstein-Barr virus in human B lymphocytes
16. Fgr expression restricted to subpopulation of monocyte/macrophage lineage in resting conditions is induced in various hematopoietic cells after activation or transformation
17. Mediation of Epstein-Barr virus EBNA2 transactivation by recombination signal-binding protein JΚ
18. A second nuclear protein is encoded by Epstein-Barr virus in latent infection
19. Activated mouse Notchl transactivates Epstein-Barr virus nuclear antigen 2-regulated viral promoters
20. Masking of the CBFI/RBPJΚ transcriptional repression domain by Epstein-Barr virus EBNA2
21. Three unrelated viral transforming proteins (vIRF, EBNA2, and EIA) induce the MYC oncogene through the interferon-responsive PRF element by using different transcription coadaptors
22. Identification of critical cis elements involved in mediating Epstein-Barr virus nuclear antigen 2-dependent activity of an enhancer located upstream of the viral Bam HI C promoter
23. Epstein-Barr virus nuclear antigen 2 is a transcriptional suppressor of the immunoglobulin μ gene: Implications for the expression of the translocated c-myc gene in Burkitt's lymphoma cells
24. Epstein-Barr virus nuclear protein 2 transactivation of the latent membrane protein I promoter is mediated by J kappa and PU.1
25. The proto-oncogene c-myc is a direct target gene of Epstein-Barr virus nuclear antigen 2
26. 1-regulating proteins by Epstein-Barr virus mutants conditional for EBNA2
27. Epstein-Barr virus nuclear antigen 2 (EBNA2)-oestrogen receptor fusion proteins complement the EBNA2-deficient Epstein-Barr virus strain P3HR1 in transformation of primary B cells but suppress growth of human B cell lymphoma lines
28. Epstein-Barr virus and its replication
29. The level of c-fgr RNA is increased by EBNA2, an Epstein-Barr virus gene required for B-cell immortalization
30. The Epstein-Barr virus (EBV) nuclear antigen 1 BamHI F promoter is activated on entry of EBV-transformed B cells into the lytic cycle
31. The Epstein-Barr virus nuclear protein encoded by the leader of the EBNA RNAs is important in B-lymphocyte transformation
32. A protein binding to the JΚ recombination sequence of immunoglobulin genes contains a sequence related to the integrase motif
33. Epstein-Barr virus latent membrane protein 2A blocks calcium mobilization in B lymphocytes
34. Identification of the coding region for a second Epstein-Barr virus nuclear antigen (EBNA2) by transfection of cloned DNA fragments
35. Transient expression of the Epstein-Barr virus LMP1 gene in human primary B cells induces cellular activation and DNA synthesis
36. c-myc activation renders proliferation of Epstein-Barr virus (EBV)-transformed cells independent of EBV nuclear antigen 2 and latent membrane protein 1
37. Epstein-Barr virus
38. Identification and expression of a nuclear antigen from the genomic region of the Jijoe strain of Epstein-Barr virus that is missing in its nonimmortalizing deletion mutant, P3HR-1
39. Expression of a second Epstein-Barr virus determined nuclear antigen in mouse cells after gene transfer with a cloned fragment of the viral genome
40. Functional replacement of the intracellular region of the Notch 1 receptor by Epstein-Barr virus nuclear antigen 2
41. Host-cell-determined methylation of specific Epstein-Barr virus promoters regulates the choice between distinct viral latency programs
42. Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain
43. Isolation of Epstein-Barr virus-negative cell clones from the EBV-positive Burkitt's lymphoma line Akata: Malignant phenotypes of BL cells are dependent on EBV
44. A modified tetracycline-regulated system provides autoregulatory, inducible expression in cultured cells and transgenic mice
45. 1 transition during immortalization of resting human B lymphocytes by Epstein-Barr virus
46. PU box-binding transcription factors and a POU domain protein cooperate in the Epstein-Barr virus (EBV) nuclear antigen 2-induced transactivation of the EBV latent membrane protein 1 promoter
47. An ATF/CRE element mediates both EBNA2-dependent and EBNA2-independent activation of the Epstein-Barr virus LMP1 gene promoter
48. Nuclear access and action of notch in vivo
49. EBNA2 transactivates a lymphoid-specific enhancer in the BamH1 C promoter of Epstein-Barr virus
50. An Epstein-Barr virus producer line Akata: Establishment of the cell line and analysis of viral DNA
51. Synchronous and sequential activation of the latently infected Epstein-Barr virus genomes
52. The many roles of c-Myc in apoptosis
53. The Epstein-Barr virus nuclear protein 2 acidic domain can interact with TFIIB, TAF40, and RPA70, but not with TBP
54. Expression of Epstein-Barr nuclear antigen 2 in kidney tubule cells induces tumors in transgenic mice
55. Novel downstream elements upregulate transcription initiated from an Epstein-Barr virus latent promoter
56. Epstein-Barr virus nuclear antigen 2 specifically induces expression of the B-cell activation antigen CD23
57. Epstein-Barr virus latent membrane protein (LMP1) and Nuclear proteins 2 and 3 C are effectors of phenotypic changes in B lymphocytes: EBNA2 and LMP1 cooperatively induce CD23
58. Epstein-Barr virus nuclear antigen 2 transactivates latent membrane protein LMP1
59. fgr is expressed in murine splenic B cells and is activated in response to antigen receptor cross-linking
60. Epstein-Barr virus nuclear protein 2 (EBNA2) binds to a component of the human SNF-SWI complex, hSNF5/Inil
61. Epstein-Barr virus nuclear antigen 2 activates transcription of the terminal protein gene
62. Epstein-Barr virus nuclear antigen 2 exerts its transactivating function through interaction with recombination signal binding protein RBP-JΚ, the homologue of Drosophila suppressor of hairless