Epstein-Barr virus nuclear protein 2 (EBNA2) binds to a component of the human SNF-SWI complex, hSNF5/Ini1

Journal of Virology

Volumn 70, Issue 9, 1996, Pages 6020-6028

  Wu, Daniel Y ^a,b   Kalpana, Ganjam V ^c   Goff, Stephen P ^d   Schubach, William H ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^d The New York Presbyterian Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEAR PROTEIN;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE ACTIVATION; CELL IMMORTALIZATION; CELL SUBPOPULATION; COMPLEX FORMATION; DELETION MUTANT; DNA BINDING; EPSTEIN BARR VIRUS; GENE EXPRESSION; GENE TARGETING; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; TRANSACTIVATION;

EID: 0029841216     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.9.6020-6028.1996     Document Type: Article

References (68)

1. Abbot, S. D., M. Rowe, K. Cadwallader, A. Ricksten, J. Gordon, F. Wang, L. Rymo, and A. B. Rickinson. 1990. Epstein-Barr virus nuclear antigen 2 induces expression of the virus-encoded latent membrane protein. J. Virol. 64:2126-2134.
2. Baer, R., A. T. Bankier, M. D. Biggin, P. L. Deininger, P. J. Farrell, T. J. Gibson, G. Hatfull, G. S. Hudson, S. C. Satchwell, C. Séguin, et al. 1984. DNA sequence and expression of the B95-8 Epstein-Barr virus genome. Nature (London) 310:207-211.
3. Bartel, P. L., C. Cheng-ting, R. Sternglanz, and S. Fields. 1943. Using the two-hybrid system to detect protein-protein interactions, p. 153-179. In D. A. Hartley (ed.), Cellular interactions in development: a practical approach. IRL Press, Oxford.
4. Bartel, P. L., C. T. Chien, R. Sternglanz, and S. Fields. 1993. Elimination of false positives that arise in using the two-hybrid system. BioTechniques 14:920-924.
5. Breeden, L., and K. Nasmyth. 1985. Regulation of the yeast HO gene. Cold Spring Harbor Symp. Quant. Biol. 50:643-650.
6. Cairns, B. R., Y. J. Kim, M. H. Sayre, B. C. Laurent, and R. D. Kornberg. 1994. A multisubunit complex containing the SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, and SNF6 gene products isolated from yeast. Proc. Natl. Acad. Sci. USA 91:1950-1954.
7. Carlson, M., and B. C. Laurent. 1994. The SNF/SWI family of global transcriptional activators. Curr. Opin. Cell Biol. 6:396-402.
8. Cohen, J. I., F. Wang, and E. Kieff. 1991. Epstein-Barr virus nuclear protein 2 mutations define essential domains for transformation and transactivation. J. Virol. 65:2545-2554.
9. Cordier, M., A. Calender, M. Billaud, U. Zimber, G. Rousselet, O. Pavlish, J. Banchereau, T. Tursz, G. Bornkamm, and G. M. Lenoir. 1990. Stable transfection of Epstein-Barr virus (EBV) nuclear antigen 2 in lymphoma cells containing the EBV P3HR1 genome induces expression of B-cell activation molecules CD21 and CD23. J. Virol. 64:1002-1013.
10. Coté, J., J. Quinn, J. L. Workman, and C. L. Peterson. 1994. Stimulation of GAL4 derivative binding to nucleosomal DNA by the yeast SWI/SNF complex. Science 265:53-60.
11. Dambaugh, T., K. Hennessy, L. Chamnankit, and E. Kieff. 1984. U2 region of Epstein-Barr virus DNA may encode Epstein-Barr nuclear antigen 2. Proc. Natl. Acad. Sci. USA 81:7632-7636.
12. Dignam, J. D., R. M. Lebovitz, and R. G. Roeder. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475-1489.
13. Dignam, J. D., P. L. Martin, B. S. Shastry, and R. G. Roeder. 1983. Eukaryotic gene transcription with purified components. Methods Enzymol. 101: 582-598.
14. DuBridge, R. B., B. Tang, H. C. Hsia, P. M. Leong, J. H. Miller, and M. P. Calos. 1987. Analysis of mutation in human cells by using Epstein-Barr virus shuttle system. Mol. Cell. Biol. 7:378-387.
15. Durfee, T., K. Becherer, P. L. Chen, S. H. Yeah, A. E. Kilburn, W. H. Lee, and S. J. Elledge. 1993. The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit. Genes Dev. 7:555-569.
16. Eisenman, R. Personal communication.
17. 2b immunoglobulins from mouse serum using protein A-Sepharose. Biochemistry 15:429-436.
18. Fahraeus, R., A. Jansson, A. Sjoblom, T. Nilsson, G. Klein, and L. Rymo. 1993. Cell phenotype-dependent control of Epstein-Barr virus latent membrane protein 1 gene regulatory sequences. Virology 195:71-80.
19. Favrot, M. C., I. Philip, T. Philip, J. Portoukalian, J. F. Doré, and G. M. Lenoir. 1984. Distinct reactivity of Burkitt's lymphoma cell lines with eight monoclonal antibodies correlated with ethnic origin. J. Natl. Cancer Inst. 73:841-847.
20. Felsenfeld, G. 1992. Chromatin as an essential part of the transcriptional mechanism. Nature (London) 355:219-224.
21. Grasser, F. A., S. Gottel, P. Haiss, B. Boldyreff, O. G. Issinger, and L. N. Mueller. 1992. Phosphorylation of the Epstein-Barr virus nuclear antigen 2. Biochem. Biophys. Res. Commun. 186:1694-1701.
22. Grasser, F. A., P. Haiss, S. Gottel, and L. N. Mueller. 1991. Biochemical characterization of Epstein-Barr virus nuclear antigen 2A. J. Virol. 65:3779-3788.
23. Henikoff, S., and M. K. Eghtedarzadeh. 1987. Conserved arrangement of nested genes in Drosophila Gart locus. Genetics 117:711-725.
24. Henkel, T., P. D. Ling, S. D. Hayward, and M. G. Peterson. 1994 Mediation of Epstein-Barr virus EBNA2 transactivation by recombination signal-binding protein J kappa. Science 265:92-95.
25. Hirschhorn, J. N., S. A. Brown, C. D. Clark, and F. Winston. 1992. Evidence that SNF2/5WI2 and SNF5 activate transcription in yeast by altering chromatin structure. Genes Dev. 6:2288-2298.
26. Hsieh, J. J., and S. D. Hayward. 1995. Masking of the CBF1/RBPJ kappa transeriptional repression domain by Epstein-Barr virus EBNA2. Science 268:560-563.
27. Imbalzano, A. N., H. Kwon, M. R. Green, and R. E. Kingston. 1994. Facilitated binding of TATA-binding protein to nucleosomal DNA. Nature (London) 370:481-485.
28. Johannsen, E., E. Koh, G. Mosialos, X. Tong, E. Kieff, and S. R. Grossman. 1995. Epstein-Barr virus nuclear protein 2 transactivation of the latent membrane protein 1 promoter is mediated by Jκ and PU.1. J. Virol. 69:253-262.
29. Kalpana, G. V., S. Marmon, W. Wang, G. R. Crabtree, and S. P. Goff. 1994. Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5. Science 266:2002-2006.
30. Khavari, P. A., C. L. Peterson, J. W. Tamkun, D. B. Mendel, and G. R. Crabtree. 1993. BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription. Nature (London) 366:170-174.
31. Knutson, J. C. 1990. The level of c-fgr RNA is increased by EBNA-2, an Epstein-Barr virus gene required for B-cell immortalization. J. Virol. 64: 2530-2536.
32. Kwon, H., A. N. Imbalzano, P. A. Khavari, R. E. Kingston, and M. R. Green. 1994. Nucleosome disruption and enhancement of activator binding by a human SWI/SNF complex. Nature (London) 370:477-481.
33. Laurent, B. C., I. Treich, and M. Carlson. 1993. Role of yeast SNF and SWI proteins in transcriptional activation. Cold Spring Harbor Symp. Quant. Biol. 58:257-263.
34. Laux, G., B. Adam, L. J. Strobl, and F. Moreau-Gachelin. 1994. The Spi-1/ PU. 1 and Spi-B ets family transcription factors and the recombination signal binding protein RBP-Jκ interact with an Epstein-Barr virus nuclear antigen 2 responsive cis-element. EMBO J. 13:5624-5632.
35. Mathison, J. C., G. D. Virca, E. Wolfson, P. S. Tobias, K. Glaser, and R. J. Ulevitch. 1990. Adaptation to bacterial lipopolysaccharide controls lipopolysaccharide-induced tumor necrosis factor production in rabbit macrophages. J. Clin. Invest. 85:1108-1118.
36. Muchardt, C., C. Sardet, B. Bourachot, C. Onufryk, and M. Yaniv. 1995. A human protein with homology to Saccharomyces cerevisiac SNF5 interacts with the potential helicase hbrm. Nucleic Acids Res. 23:1127-1132.
37. Muchardt, C., and M. Yaniv. 1993. A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcription activation by the glucocorticoid receptor. EMBO J. 12:4279-4290.
38. Peterson, C. L., and J. W. Tamkun. 1995. The SWI-SNF complex: a chromatin remodeling machinery. Trends Biochem. Sci. 20:143-146.
39. Petti, L., C. Sample, and E. Kieff. 1990. Subnuclear localization and phosphorylation of Epstein-Barr virus latent infection nuclear proteins. Virology 176:563-574.
40. Puissant, C., and L. M. Houdabine. 1990. Method of RNA isolation by acid-guanidinium thiocyanate-phenol-chloroform extraction. BioTechniques 8:148-149.
41. Quinn, J., A. M. Fyrberg, R. W. Ganster, M. C. Schmidt, and C. L. Peterson. 1996. DNA-binding properties of the yeast SWI/SNF complex. Nature (London) 379:844-847.
42. Rabson, M., L. Gradoville, L. Heston, and G. Miller. 1982. Nonimmortalizing P3J-HR-1 Epstein-Barr virus: a deletion mutant of its transforming parent, Jijoye. J. Virol. 44:834-844.
43. Ragona, G., I. Ernberg, and G. Klein. 1980. Induction and biological characterization of the Epstein-Barr virus (EBV) carried by the Jijoye lymphoma line. Virology 101:553-557.
44. Sairenji, T., and Y. Hinuma. 1980. Re-evaluation of transforming strain of Epstein-Barr virus from the Burkitt lymphoma cell line, Jijoye. Int. J. Cancer 26:337-342.
45. Sanger, F., S. Nicklen, and A. R. Coulson. 1977. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74:5463-5467.
46. Schiestl, R. H., and R. D. Geitz. 1989. High efficiency transformation of intact yeast cells using single stranded nucleic acid as carrier. Curr. Genet. 16:339-346.
47. Schubach, W. H., G. Horvath, B. Spoth, and J. C. Hearing. 1991. Expression of Epstein-Barr virus nuclear antigen 2 in insect cells from a baculovirus vector. Virology 185:428-431.
48. Smith, D. E., and P. A. Fisher. 1984. Identification, developmental regulation, and response to heat shock of two antigenically related forms of a major nuclear envelope protein in Drosophila embryo: application of an improved method for affinity purification of antibodies using polypeptides immobilized on nitrocellulose blots. J. Cell Biol. 99:20-28.
49. Straus, S. E., J. I. Cohen, G. Tosato, and J. Meier. 1993. NIH conference. Epstein-Barr virus infections: biology, pathogenesis, and management. Ann. Intern. Med. 118:45-58.
50. Sung, N. S., S. Kenney, D. Gutsch, and J. S. Pagano. 1991. EBNA-2 transactivates a lymphoid-specitic enhancer in the BamHI C promoter of Epstein-Barr virus. J. Virol. 65:2164-2169.
51. Tamkun, J. W., R. Deuring, M. P. Scott, M. Kissinger, A. M. Pattalucci, T. C. Kaufman, and J. A. Kennison. 1992. brama: a regulator of Drosophila homeotic genes structurally related to the yeast transcription activator SNF2/ SWI2. Cell 68:561-572.
52. Tong, X., R. Drapkin, D. Reinberg, and E. Kieff. 1995. The 62- and 80-kDa suhunits of transcription factor IIH mediate the interaction with Epstein-Barr virus nuclear protein 2. Proc. Natl. Acad. Sci. USA 92:3259-3263.
53. Tong, X., R. Drapkin, R. Yalamanchili, G. Mosialos, and E. Kieff. 1995. The Epstein-Barr virus nuclear protein 2 acidic domain forms a complex with a novel cellular coactivator that can interact with TFIIE. Mol. Cell. Biol. 15:4735-4744.
54. Tong, X., F. Wang, C. J. Thut, and E. Kieff. 1995. The Epstein-Barr virus nuclear protein 2 acidic domain can interact with TFIIB, TAF40, and RPA70 but not with TATA-binding protein. J. Virol. 69:585-588.
55. Tsang, S. F., F. Wang, K. M. Izumi, and E. Kieff. 1991. Delineation of the cis-acting element mediating EBNA-2 transactivation of latent infection membrane protein expression. J. Virol. 65:6765-6771.
56. Tsui, S., and W. H. Schubach. 1994. Epstein-Barr virus nuclear protein 2A forms oligomers in vitro and in vivo through a region required for B-cell transformation. J. Virol. 68:4287-4294.
57. Waltzer, L., F. Logeat, C. Brou, A. Israel, A. Sergeant, and E. Manet. 1994. The human J kappa recombination signal sequence binding protein (RBP-J kappa) targets the Epstein-Barr virus EBNA2 protein to its DNA responsive elements. EMBO J. 13:5633-5638.
58. Wang, F., C. Gregory, C. Sample, M. Rowe, D. Liebowitz, R. Murray, A. Rickinson, and E. Kieff. 1990. Epstein-Barr virus latent membrane protein (LMP1) and nuclear proteins 2 and 3C are effectors of phenotypic changes in B lymphocytes: EBNA-2 and LMP1 cooperatively induce CD23. J. Virol. 64:2309-2318.
59. Wang, F., C. D. Gregory, M. Rowe, A. B. Rickinson, D. Wang, M. Birkenbach, H. Kikutani, T. Kishimoto, and E. Kieff. 1987. Epstein-Barr virus nuclear antigen 2 specifically induces expression of the B-cell activation antigen CD23. Proc. Natl. Acad. Sci. USA 84:3452-3456.
60. Wang, F., H. Kikutani, S. F. Tsang, T. Kishimoto, and E. Kieff. 1991. Epstein-Barr virus nuclear protein 2 transactivates a cis-acting CD23 DNA element. J. Virol. 65:4101-4106.
61. Wang, F., S. F. Tsang, M. G. Kurilla, J. I. Cohen, and E. Kieff. 1990. Epstein-Barr virus nuclear antigen 2 transactivates latent membrane protein LMP1. J. Virol. 64:3407-3416.
62. Wilson, C. J., D. M. Chao, A. N. Imbalzano, G. R. Schnitzler, R. E. Kingston, and R. A. Young. 1996 RNA polymerase II holoenzyme contains SWI/SNF regulators involved in chromatin remodeling. Cell 84:235-244.
63. Winston, F., and M. Carlson. 1992. Yeast SNF/SWI transcriptional activators and the SPT/SIN chromatin connection. Trends Genet. 8:387-391.
64. Wolffe, A. P., and J. J. Hayes. 1993. Transcription factor interaction with model nucleosome templates. Methods Mol. Genet. 2:314-329.
65. Workman, J. L., and R. E. Kingston. 1992. Nucleosome core displacement in vitro via a metastable transcription factor:nucleosome complex. Science 258: 1780-1784.
66. Zimber-Strobl, U., F. Kremmer, F. Grasser, G. Marshall, G. Lanx, and G. Bornkamm. 1993. The Epstein-Barr virus nuclear antigen 2 interacts with an EBNA2 responsive cis-element of the terminal protein 1 gene promoter. EMBO J. 12:167-175.
67. Zimber-Strobl, U., L. J. Strobl, C. Meitinger, R. Hinrichs, T. Sakai, T. Furukawa, T. Honjo, and G. W. Bornkamm. 1994. Epstein-Barr virus nuclear antigen 2 exerts its transactivating function through interaction with recombination signal binding protein RBP-J kappa, the homologue of Drosophila Suppressor of Hairless. EMBO J. 13:4973-4982.
68. Zimber-Strobl, U., K. O. Suentzenich, G. Laux, D. Eick, M. Cordier, A. Calender, M. Billaud, G. M. Lenoir, and G. W. Bornkamm. 1991. Epstein-Barr virus nuclear antigen 2 activates transcription of the terminal protein gene. J. Virol. 65:415-423.