The in vivo relevance of the varied channel-blocking properties of uncompetitive NMDA antagonists: Tests on spinal neurones

Neuropharmacology

Volumn 41, Issue 1, 2001, Pages 50-61

  Jones, M W ^a,c   McClean, M ^a   Parsons, C G ^b   Headley, P M ^a  

^a SCHOOL OF MEDICAL SCIENCES   (United Kingdom)

^b MERZ PHARMACEUTICALS GMBH   (Germany)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Inflammation; N methyl D aspartate; Nociception; Spinal cord; Voltage dependence; Wind up

Indexed keywords

DIZOCILPINE; GLYCINE; INDICATOR; KETAMINE; MEMANTINE; MRZ 2 502; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; STRYCHNINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; CELL MEMBRANE DEPOLARIZATION; COMPARATIVE STUDY; CONTROLLED STUDY; DIAGNOSTIC TEST; DOSE RESPONSE; DRUG BINDING; DRUG EFFECT; DRUG EFFICACY; ELECTRIC POTENTIAL; ELECTROSTIMULATION; IN VITRO STUDY; IN VIVO STUDY; IONTOPHORESIS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RESPONSE TIME; SPIKE; SPINAL CORD NERVE CELL; SYNAPTIC POTENTIAL;

ANIMALS; DIZOCILPINE MALEATE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHYSIOLOGY; EXCITATORY AMINO ACID ANTAGONISTS; IONTOPHORESIS; KETAMINE; MALE; MEMANTINE; NEURONS; PHYSICAL STIMULATION; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; SPINAL CORD;

EID: 0034964563     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(01)00041-7     Document Type: Article

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