Identification of a native low-conductance NMDA channel with reduced sensitivity to Mg2+ in rat central neurones

Journal of Physiology

Volumn 494, Issue 2, 1996, Pages 479-492

  Momiyama, Akiko ^a   Feldmeyer, Dirk ^a,b   Cull Candy, Stuart G ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

7 CHLOROKYNURENIC ACID; GLYCINE; MAGNESIUM ION; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROTEIN SUBUNIT; RECEPTOR SUBTYPE;

ANIMAL CELL; ARTICLE; CENTRAL NERVOUS SYSTEM; CEREBELLUM NUCLEUS; CHANNEL GATING; CONTROLLED STUDY; MEMBRANE CHANNEL; MEMBRANE CONDUCTANCE; NERVE CELL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PURKINJE CELL; RAT; SPINAL CORD DORSAL HORN;

EID: 0029817421     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.1996.sp021507     Document Type: Article

References (45)

1. AKAZAWA, C., SHIGEMOTO, R., BESSHO, Y., NAKANISHI, S. & MIZUNO, N. (1994). Differential expression of five N-methyl-D-aspartate receptor subunit mRNAs in the cerebellum of developing and adult rats. Journal of Comparative Neurology 347, 150-160.
2. ASCHER, P., BREGESTOVSKI, P. & NOWAK, L. (1988). N-methyl-D-aspartate-activated channels of mouse central neurones in magnesium-free solutions. Journal of Physiology 399, 207-226.
3. ASCHER, P. & JOHNSON, J. W. (1994). The NMDA receptor, its channel, and its modulation by glycine. In The NMDA Receptor, 2nd edn, ed. COLLINGRIDGE, G. L. & WATKINS, J. C., pp. 177-205. Oxford University Press, Oxford.
4. ASCHER, P. & NOWAK, L. (1988). The role of divalent cations in the N-methyl-D-aspartate responses of mouse centra] neurones in culture. Journal of Physiology 399, 247-266.
5. CARMIGNOTO, G. & VICINI, S. (1992). Activity-dependent decrease in NMDA receptor responses during development of the visual cortex. Science 258, 1007-1011.
6. COLQUHOUN, D. & SIGWORTH, F. J. (1995). Fitting and statistical analysis of single-channel records. In Single-Channel Recording, 2nd edn, ed. SAKMANN, B. & NEHER, E., pp. 483-587. Plenum Press, New York.
7. CREPEL, F. & AUDINAT, E. (1991). Excitatory amino acid receptors of cerebellar Purkinje cells: development and plasticity Progress in Biophysics and Molecular Biology 55, 31-46.
8. CREPEL, F., DELHAYE-BOUCHAUD, N. & DUPOST, J. L. (1981). Fate of the multiple innervation of cerebellar Purkinje cells by climbing fibers in immature control, x-irradiated and hypothyroid rats. Developmental Brain Research 1, 59-71.
9. CULL-CANDY, S. G., FARRANT, M. & FELDMEYER, D. (1995). NMDA channel conductance: a user's guide. In Excitatory Amino Acids and Synaptic Transmission, ed. WHEAL, H. V. & THOMPSON, A. M., pp. 121-132. Academic Press, London.
10. CULL-CANDY, S. G., HOWE, J. R. & USOWICZ, M. M. (1987). Single glutamate-receptor channels in two types of cerebellar neurones. In Excitatory Amino Acids in Health and Disease, ed. LODGE, D., pp. 165-185. Wiley, London.
11. CULL-CANDY, S. G. & USOWICZ, M. M. (1987). Multiple-conductance channels activated by excitatory amino acids in cerebellar neurons. Nature 325, 525-528.
12. CULL-CANDY, S. G. & USOWICZ, M. M. (1989). On the multiple-conductance single channels activated by excitatory amino acids in large cerebellar neurones of the rat. Journal of Physiology 415, 555-582.
13. FARRANT, M. & CULL-CANDY, S. G. (1991). Excitatory amino acid receptor-channels in Purkinje cells in thin cerebellar slices. Proceedings of the Royal Society B 244, 179-184.
14. FARRANT, M., FELDMEYER, D., TAKAHASHI, T. & CULL-CANDY, S. G. (1994). NMDA-receptor channel diversity in the developing cerebellum. Nature 368, 335-339.
15. FELDMEYER, D., FARRANT, M. & CULL-CANDY, S. G. (1995). Macroscopic kinetic properties of NMDA receptors in patches from granule cells of the rat. cerebellum. Journal of Physiology 489.P, 14P.
16. HESTRIN, S. (1992). Developmental regulation of NMDA receptor-mediated synaptic currents at a central synapse. Nature 357, 686-689.
17. HOLLMANN, M., BOULTER, J., MARON, C., BEASLEY, L., SULLIVAN, J., PECHT, G. & HEINEMANN, S. (1993). Zinc potentiates agonist-induced currents at certain splice variants of the NMDA receptor. Neuron 10, 943-954.
18. IKEDA, K., NAGASAWA, M., MORI, H., ARAKI, K., SAKIMURA, K., WATANABE, M., INOUE, Y. & MISHINA, M. (1992). Cloning and expression of the e4 subunit of the NMDA receptor channel. FEBS Letters 313, 34-38.
19. ISHII, T., MORIYOSHI, K., SUGIHARA, H., SAKURADA, K., KADOTANI, H., YOKOI, M., AKAZAWA, C., SHIOEMOTO, R., MIZUNO, N., MASU, M. & NAKANISHI, S. (1993). Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits. Journal of Biological Chemistry 268, 2836-2843.
20. JAHR, C. E. & STEVENS, C. F. (1987). Glutamate activates multiple single channel conductances in hippocampal neurons. Nature 325, 522-525.
21. KOURIE, J. I., LAVER, D. R., JUNANKAR, P. R., GAGE, P. W. & DULHUNTY, A. F. (1996). Characteristics of two types of chloride channel in sarcoplasmic reticulum vesicles from rabbit skeletal muscle. Biophysical Journal 70, 202-221.
22. KUTSUWADA, T., KASHIWABUCHI, N., MORI, H., SAKIMURA, K., KUSHIYA, E., ARAKI, K., MEGURO, H., MASAKI, H., KUMANISHI, T., ARAKAWA, M. & MISHINA, M. (1992). Molecular diversity of the NMDA receptor channel, Nature 358, 36-41.
23. LLANO, I., MARTY, A., ARMSTRONG, C. M. & KONNERTH, A. (1991). Synaptic- and agonist-induced excitatory currents of Purkinje cells in rat cerebellar slices. Journal of Physiology 434, 183-213.
24. MCBAIN, C. J. & MAYER, M. L. (1994). N-methyl-D-aspartic acid receptor structure and function. Physiological Reviews 74, 723-760.
25. MARIANI, J. & CHANGEUX, J.-P. (1981). Ontogenesis of olivocerebellar relationships. I. Studies by intracellular recordings of the multiple innervation of Purkinje cells by climbing fibers in the developing rat cerebellum. Journal of Neuroscience 1, 696-702.
26. 2+ of NMDA responses in spinal cord neurons. Nature 309, 261-263.
27. MEGURO, H., MORI, H., ARAKI, K., KUSHIYA, E., KUTSUWADA, T., YAMAZAKI, M., KUMANISHI, T., ARAKAWA, M., SAKIMURA, K. & MISHINA, M. (1992). Functional characterization of a heteromeric NMDA receptor channel expressed from cloned cDNAs. Nature 357, 70-74.
28. MOMIYAMA, A., FELDMEYER, D. & CULL-CANDY, S. G. (1995). Single channel characteristics of NMDA receptors in Purkinje cells in thin slices of neonatal rat cerebellum. Journal of Physiology 483.P, 162P.
29. MONYER, H., SPRENGEL, R., SCHOEPFER, R., HERB, A., HIGUCHI, M., LOMELI, H., BURNASHEV, N., SAKMANN, B. & SEEBURG, P. H. (1992). Heteromeric NMDA receptors: Molecular and functional distinction of subtypes. Science 256, 1217-1221.
30. MONYER, H., BURNASHEV, N., LAURIE, D. J., SAKMANN, B. & SEEBURG, P. H. (1994). Developmental and regional expression in the rat brain and functional properties of four NMDA receptors. Neuron 12, 529-540.
31. MORIYOSHI, K., MASU, M., ISHII, T., SHIGEMOTO, R., MIZUNO, N. & NAKANISHI, S. (1991). Molecular cloning and characterization of the rat NMDA receptor. Nature 354, 31-37.
32. NOWAK, L., BREGESTOVSKI, P., ASCHER, P., HERBET, A. & PROCHIANTZ, A. (1984). Magnesium gates glutamate-activated channels in mouse central neurones. Nature 307, 462-465.
33. PERKEL, D. J., HESTRIN, S., SAH, P. & NICOLL, R. A. (1990). Excitatory synaptic currents in Purkinje cells. Proceedings of the Royal Society B 241, 116-121.
34. PETRALIA, R. S., WANG, Y.-X. & WENTHOLD, R. J. (1994). The NMDA receptor subunits NR2A and NR2B show histological and ultrastructural localization patterns similar to those of NR1. Journal of Neuroscience 14, 6102-6120.
35. RABAPCCHI, S., BAILLY, Y., DELHAYE-BOUCHAUD, N. & MARIANI, J. (1992). Involvement of the N-methyl-D-aspartate (NMDA) receptor in synapse elimination during cerebellar development. Science 256, 1823-1825.
36. ROSENMUND, C., LEGENDRE, P. & WESTBROOK, G. L. (1992). Expression of NMDA channels on cerebellar Purkinje cells acutely dissociated from newborn rats. Journal of Neurophysiology 68, 1901-1905.
37. SHENG, M., CUMMINGS, J., ROLDAN, L. A., JAN, Y. N. & JAN, L. Y. (1994). Changing subunit composition of heteromeric NMDA receptors during development of rat cortex. Nature 368, 144-147.
38. STERN, P., BÉHÉ, P., SCHOEPFER, B. & COLQUHOUN, D. (1992). Single-channel conductances of NMDA receptors expressed from cloned cDNAs: comparison with native receptors. Proceedings of the Royal Society B 250, 271-277.
39. TOLLE, T. R., BERTHELE, A., ZIEGLUÄNSBERGER, W., SEEBURG, P. H. & WISDEN, W. (1993). The differential expression of 16 NMDA and non-NMDA receptor subunits in the rat spinal cord and in periaqueductal gray. Journal of Neuroscience 13, 5009-5028.
40. TSUZUKI, K., MOCHIZUKI, S., IINO, M., MORI, H., MISHINA, M. & OZAWA, S. (1994). Ion permeation properties of the cloned mouse ε2/ζ1 NMDA receptor channel. Molecular Brain Research 26, 37-46.
41. WAFFORD, K. A., BAIN, C. J., LE-BOURDELLES, B., WHITING, P. J. & KEMP, J. A. (1993). Preferential co-assembly of recombinant NMDA receptors composed of three different subunits. NeuroReport 4, 1347-1349.
42. WATANABE, M., MISHINA, M. & INOUE, Y. (1994a). Distinct spatiotemporal distribution of the N-methyl-D-aspartate receptor channel subunit mRNAs in the mouse cervical cord. Journal of Comparative Neurology 345, 314-319.
43. WATANABE, M., MISHINA, M. & INOUE, Y. (1994b). Distinct spatiotemporal expressions of five NMDA receptor channel subunit mRNAs in the cerebellum. Journal of Comparative Neurology 345, 513-519.
44. WYLLIE, D., BÉHÉ, P., EDMONDS, B., NASSAR, M., SCHOEPFER, R. & COLQUHOUN, D. (1995). Whole-cell and single-channel currents from recombinant NMDA NR1/2D receptors expressed in Xenopus oocytes. Journal of Physiology 491.P, 135P.
45. YAMAZAKI, M., MORI, H., ARAKI, K., MORI, K. J. & MISHINA, M. (1992). Cloning, expression and modulation of a mouse NMDA receptor subunit. FEBS Letters 300, 39-45.