Switch in chemokine receptor phenotype on memory T cells without a change in the cytokine phenotype

Scandinavian Journal of Immunology

Volumn 54, Issue 1-2, 2001, Pages 100-108

  Aarvak, T ^a   Strand, E ^a   Teigland, J ^a   Miossec, P ^b   Natvig, J B ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b EDOUARD HERRIOT HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR3; CHEMOKINE RECEPTOR CCR5; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 4;

ARTICLE; CELL LINE; CLINICAL ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LYMPHOCYTE CLONE; LYMPHOCYTE MIGRATION; MEMORY CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; SYNOVIUM; TH1 CELL; TH2 CELL;

ARTHRITIS, RHEUMATOID; CELL MOVEMENT; IMMUNOLOGIC MEMORY; IMMUNOPHENOTYPING; INTERFERON TYPE II; INTERLEUKIN-2; INTERLEUKIN-4; RECEPTORS, CCR5; RECEPTORS, CHEMOKINE; TH1 CELLS; TH2 CELLS;

EID: 0034963089     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.2001.00957.x     Document Type: Article

References (36)

1. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
2. TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
3. Genetic susceptibility to Leishmania: IL-12 responsiveness in TH1 cell
4. Functional diversity of helper T lymphocytes
5. Acquisition of lymphokine-producing phenotype by CD4+ T cells
6. Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells
7. IL-17 Is produced by some proinflammatory Th1/Th0 cells but not by Th2 Cells
8. Interferon-gamma and B cell stimulatory factor-1 reciprocally regulate Ig isotype production
9. Th1/Th2 subsets: Distinct differences in homing and chemokine receptor expression?
10. Chemokines: Signal lamps for trafficking of T and B cells for development and effector function
11. Chemokines and chemokine receptors in T-cell priming and Th1/Th2- mediated responses
12. Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s
13. The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions
14. Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells
15. Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes
16. Cellular basis for rheumatoid inflammation
17. Rheumatoid inflammatory T-cell clones express mostly Th1 but also Th2 and mixed (Th0-like) cytokine patterns
18. Activation of dual T cell signaling pathways by the chemokine RANTES
19. Detection of activated T cell products in the rheumatoid joint using cDNA probes to Interleukin-2 (IL-2) IL-2 receptor and IFN-gamma
20. Bypassing the antigen to control rheumatoid arthritis
21. Change in the Th1/Th2 phenotype of memory T-cell clones from rheumatoid arthritis synovium
22. Changes in the Th1 or Th2 cytokine dominance in the synovium of rheumatoid arthritis (RA): A kinetic study of the Th subsets in one unusual RA patient
23. Classification and epidemiology
24. T gamma delta cells in juvenile rheumatoid arthritis and rheumatoid arthritis. In the juvenile rheumatoid arthritis synovium the T gamma delta cells express activation antigens and are predominantly V delta 1 +, and a significant proportion of these patients have elevated percentages of T gamma delta cells
25. Chemokine receptor usage by human eosinophils. The importance of CCR3 demonstrated using an antagonistic monoclonal antibody
26. CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia
27. Reversibility of T helper 1 and 2 populations is lost after long-term stimulation
28. Stability of Th1 and Th2 populations
29. CCR5 is characteristic of Th1 lymphocytes
30. Switch in chemokine receptor expression upon TCR stimulation reveals novel homing potential for recently activated T cells
31. The cytokines IL-4, IFN-gamma, and IL-12 regulate the development of subsets of memory effector helper T cells in vitro
32. Reciprocal regulatory effects of IFN-gamma and IL-4 on the in vitro development of human Th1 and Th2 clones
33. IL-4 and IFN (alpha and gamma) exert opposite regulatory effects on the development of cytolytic potential by Th1 or Th2 human T cell clones
34. Multistep navigation and the combinatorial control of leukocyte chemotaxis
35. Differential CC chemokine-induced enhancement of T helper cell cytokine production
36. C-C chemokines differentially alter interleukin-4 production from lymphocytes