Cepharanthine activates caspases and induces apoptosis in Jurkat and K562 human leukemia cell lines

Journal of Cellular Biochemistry

Volumn 82, Issue 2, 2001, Pages 200-214

  Wu, Jianghong ^a   Suzuki, Haruhiko ^a   Zhou, Yan Wen ^a   Liu, Wei ^a   Yoshihara, Motoi ^a   Kato, Masashi ^a   Akhand, Anwarul A ^a   Hayakawa, Akemi ^a   Takeuchi, Kei ^a   Hossain, Khaled ^a   Kurosawa, Mio ^a   Nakashima, Izumi ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Apoptosis; Bcr Abl; Caspase; Cepharanthine; Fas; Herbimycin A; Human leukemia cells; Signal transduction

Indexed keywords

BCR ABL PROTEIN; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE; CASPASE 3; CASPASE 8; CASPASE 9; CEPHARANTHINE; FAS ANTIBODY; HERBIMYCIN A; HYBRID PROTEIN; LAMIN B;

APOPTOSIS; ARTICLE; BONE MARROW TOXICITY; CHRONIC MYELOID LEUKEMIA; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION;

ALKALOIDS; AMINO ACID CHLOROMETHYL KETONES; ANTIGENS, CD95; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BENZOQUINONES; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CARRIER PROTEINS; CASPASES; CYSTEINE PROTEINASE INHIBITORS; DNA FRAGMENTATION; DRUG SCREENING ASSAYS, ANTITUMOR; DRUG SYNERGISM; ENZYME ACTIVATION; ENZYME INHIBITORS; FAS LIGAND PROTEIN; FUSION PROTEINS, BCR-ABL; HUMANS; INTRACELLULAR MEMBRANES; JURKAT CELLS; K562 CELLS; LACTAMS, MACROCYCLIC; LAMIN TYPE B; LAMINS; MEMBRANE GLYCOPROTEINS; MITOCHONDRIA; NEOPLASM PROTEINS; NUCLEAR PROTEINS; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; QUINONES;

EID: 0034952118     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.1155     Document Type: Article

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