Protein kinase C and phosphatidylinositol 3-kinase independently contribute to P-glycoprotein-mediated drug secretion in the mouse proximal tubule

Pflugers Archiv European Journal of Physiology

Volumn 442, Issue 3, 2001, Pages 321-328

  Tsuruoka, Shuichi ^a   Sugimoto, Koh Ichi ^a   Fujimura, Akio ^a   Imai, Masashi ^a   Asano, Yasushi ^a   Muto, Shigeaki ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

mdr1a gene; mdr1b gene; P glycoprotein; Phosphatidylinositol 3 kinase; Protein kinase C

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; GLYCOPROTEIN P; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE C; RHODAMINE 123; STAUROSPORINE; VERAPAMIL; WORTMANNIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ELIMINATION; DRUG TRANSPORT; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; KIDNEY PROXIMAL TUBULE; MOUSE; NONHUMAN; PERFUSION; PRIORITY JOURNAL;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; FLUORESCENT DYES; KIDNEY TUBULES, PROXIMAL; MALE; MICE; MICE, KNOCKOUT; P-GLYCOPROTEINS; PROTEIN KINASE C; RHODAMINE 123;

EID: 0034950737     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004240100542     Document Type: Article

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