Analysis of gene polymorphisms in interleukin-10 and transforming growth factor-β1 in sarcoidosis

Sarcoidosis Vasculitis and Diffuse Lung Diseases

Volumn 18, Issue 2, 2001, Pages 165-169

  Murakozy G ^a   Gaede, K I ^a   Zissel, G ^a   Schlaak, M ^a   Muller Quernheim J ^a  

^a RESEARCH CENTER BORSTEL   (Germany)

Author keywords

Gene Polymorphisms; IL 10; Sarcoidosis; TGF 1

Indexed keywords

INTERLEUKIN 10; TRANSFORMING GROWTH FACTOR BETA1;

ADULT; ALLELE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE CLASSIFICATION; DISEASE COURSE; DNA MODIFICATION; FEMALE; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENOTYPE; GRANULOMATOSIS; HUMAN; IMMUNOREGULATION; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION MAPPING; SARCOIDOSIS; STATISTICAL ANALYSIS;

ADULT; DISEASE PROGRESSION; FEMALE; GENOTYPE; HUMANS; INTERLEUKIN-10; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; PROGNOSIS; RETROSPECTIVE STUDIES; SARCOIDOSIS; TRANSFORMING GROWTH FACTOR BETA;

EID: 0034950725     PISSN: 11240490     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Sarcoidosis: Immunopathogenetic concepts and their clinical application
2. Cells and cytokines involved in the pathogenesis of sarcoidosis
3. Enhanced expression of 1L-12 associated with Th1 cytokine profiles in active pulmonary sarcoidosis
4. Anti-inflammatory cytokine release by alveolar macrophages in pulmonary sarcoidosis
5. Genotypic variation in the transforming growth factor-beta1 gene: Association with transforming growth factor-beta1 production, fibrotic lung disease, and graft fibrosis after lung transplantation
6. An investigation of polymorphism in the interleukin-10 gene promoter
7. Occurrence and clinical relevance of an interleukin-4 gene polymorphism in patients with multiple sclerosis
8. HLA-DR predicts the prognosis in Scandinavian patients with pulmonary sarcoidosis
9. Genetics of sarcoidosis
10. Analysis of MHC encoded antigen-processing genes TAP1 and TAP2 polymorphisms in sarcoidosis
11. Familial sarcoidosis is linked to the major histocompatibility complex region
12. ATS/ERS/WASOG statement on sarcoidosis. American Thoracic Society/European Respiratory Society/World Association of Sarcoidosis and other Granulomatous Disorders
13. Serum markers for the staging of disease activity of sarcoidosis and other interstitial lung diseases of unknown etiology
14. Sarcoidosis: TNF-alpha release from alveolar macrophages and serum level of s1L-2R are prognostic markers
15. Pulmonary sarcoidosis: A disorder mediated by excess helper T- lymphocyte activity at sites of disease activity
16. ARMS-PCR methodologies to determine 1L-10, TNF-alpha, TNF-beta and TGF-beta gene polymorphisms
17. Is the different T helper cell activity in sarcoidosis and extrinsic allergic alveolitis also reflected by the cellular bronchoalveolar lavage fluid profile?
18. Inflammatory and immunomodulatory roles of TGF-beta
19. TGF-beta1 DNA polymorphisms, protein levels, and blood pressure
20. An assessment of peripheral immunity in patients with sarcoidosis using measurements of serum vitamin D3, cytokines and soluble CD23
21. Interleukin-10 secretion by alveolar macrophages and monocytes in sarcoidosis
22. Cytokine mRNA gene expression in active and nonactive pulmonary sarcoidosis
23. Structure of the mouse IL-10 gene and chromosomal localization of the mouse and human genes
24. Allele frequencies of polymorophisms of the tumour necrosis factor-alpha, interleukin-10, interferon-gamma and interleukin-2 genes in a north European caucasoid group from the UK
25. Genotyping for polymorphisms in interferon-gamma, interleukin-10, transforming growth factor-beta 1 and turnout necrosis factor-alpha genes: A technical report