메뉴 건너뛰기




Volumn 156, Issue 12, 1996, Pages 4952-4960

Enhanced expression of IL-12 associated with Th1 cytokine profiles in active pulmonary sarcoidosis

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 4;

EID: 15844421725     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (338)

References (73)
  • 2
    • 0023106060 scopus 로고
    • Current concepts of pathogenesis of sarcoidosis
    • Thomas, P. D., and G. W. Hunninghake. 1987. Current concepts of pathogenesis of sarcoidosis. Am. Rev. Respir. 135:747.
    • (1987) Am. Rev. Respir. , vol.135 , pp. 747
    • Thomas, P.D.1    Hunninghake, G.W.2
  • 3
    • 0023805925 scopus 로고
    • Spontaneous expression of the interleukin 2 receptor gene and presence of functional interleukin 2 receptors on T lymphocytes in the blood of individuals with active pulmonary sarcoidosis
    • Konishi, K., D. R. Moller, C. Saltini, M. Kirby, and R. G. Crystal. 1988. Spontaneous expression of the interleukin 2 receptor gene and presence of functional interleukin 2 receptors on T lymphocytes in the blood of individuals with active pulmonary sarcoidosis. J. Clin. Invest. 82:775.
    • (1988) J. Clin. Invest. , vol.82 , pp. 775
    • Konishi, K.1    Moller, D.R.2    Saltini, C.3    Kirby, M.4    Crystal, R.G.5
  • 4
    • 0023717339 scopus 로고
    • Bias toward use of a specific T cell receptor β-chain variable region in a subgroup of individuals with sarcoidosis
    • Moller, D. R., K. Konishi, M. Kirby, B. Balbi, and R. G. Crystal. 1988. Bias toward use of a specific T cell receptor β-chain variable region in a subgroup of individuals with sarcoidosis. J. Clin. Invest. 82:1183.
    • (1988) J. Clin. Invest. , vol.82 , pp. 1183
    • Moller, D.R.1    Konishi, K.2    Kirby, M.3    Balbi, B.4    Crystal, R.G.5
  • 6
    • 0028102329 scopus 로고
    • Selective activation and accumulation of oligoclonal Vβ-specific T cells in active pulmonary sarcoidosis
    • Forman, J. D., J. T. Klein, R. F. Silver, M. C. Liu, B. M. Greenlee, and D. R. Moller. 1994. Selective activation and accumulation of oligoclonal Vβ-specific T cells in active pulmonary sarcoidosis. J. Clin. Invest. 94:1533.
    • (1994) J. Clin. Invest. , vol.94 , pp. 1533
    • Forman, J.D.1    Klein, J.T.2    Silver, R.F.3    Liu, M.C.4    Greenlee, B.M.5    Moller, D.R.6
  • 8
    • 0028977925 scopus 로고
    • Selection of oligoclonal Vβ-specific T-cells in the intradermal response to Kveim-Siltzbach reagent in individuals with sarcoidosis
    • Klein, J. T., T. D. Horn, J. D. Forman, R. F. Silver, A. L. Teirstein, and D. R. Moller. 1994. Selection of oligoclonal Vβ-specific T-cells in the intradermal response to Kveim-Siltzbach reagent in individuals with sarcoidosis. J. Immunol. 154:1450.
    • (1994) J. Immunol. , vol.154 , pp. 1450
    • Klein, J.T.1    Horn, T.D.2    Forman, J.D.3    Silver, R.F.4    Teirstein, A.L.5    Moller, D.R.6
  • 9
    • 0024353079 scopus 로고
    • Th1 and Th2 cells: Different patterns of lymphokine secretion lead to different functional properties
    • Mossman, T. R., and R. L. Coffman. 1989. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:145.
    • (1989) Annu. Rev. Immunol. , vol.7 , pp. 145
    • Mossman, T.R.1    Coffman, R.L.2
  • 10
    • 0024472155 scopus 로고
    • Regulation of T-cell activation: Differences among T-cell subsets
    • Gadjewski, T. F., S. R. Schell, G. Nau, and F. W. Fitch. 1989. Regulation of T-cell activation: differences among T-cell subsets. Immunol. Rev. 111:79.
    • (1989) Immunol. Rev. , vol.111 , pp. 79
    • Gadjewski, T.F.1    Schell, S.R.2    Nau, G.3    Fitch, F.W.4
  • 11
    • 0025733855 scopus 로고
    • The role of IL-10 in cross-regulation of Th1 and Th2 responses
    • Mossman, T. R., and K. W. Moore. 1991. The role of IL-10 in cross-regulation of Th1 and Th2 responses. Immunol. Today 12:A49.
    • (1991) Immunol. Today , vol.12
    • Mossman, T.R.1    Moore, K.W.2
  • 12
    • 0024540908 scopus 로고
    • Reciprocal expression of interferon-γ or IL-4 during the resolution or progression of murine leishmaniasis: Evidence for expansion of distinct helper T cell subsets
    • Heinzel, F. P., M. D. Sadick, B. J. Holaday, R. L. Coffman, and R. M. Locksley. 1989. Reciprocal expression of interferon-γ or IL-4 during the resolution or progression of murine leishmaniasis: evidence for expansion of distinct helper T cell subsets. J. Exp. Med. 169:59.
    • (1989) J. Exp. Med. , vol.169 , pp. 59
    • Heinzel, F.P.1    Sadick, M.D.2    Holaday, B.J.3    Coffman, R.L.4    Locksley, R.M.5
  • 13
    • 0026708718 scopus 로고
    • Regulation of immunity to parasites by T cells and T cell-derived cytokines
    • Sher, A., and R. L. Coffman. 1992. Regulation of immunity to parasites by T cells and T cell-derived cytokines. Annu. Rev. Immunol. 10:385.
    • (1992) Annu. Rev. Immunol. , vol.10 , pp. 385
    • Sher, A.1    Coffman, R.L.2
  • 15
    • 0025918158 scopus 로고
    • + T-cell subsets producing a selective pattern of lymphokines in the pathogenesis of human chronic inflammatory and allergic diseases
    • + T-cell subsets producing a selective pattern of lymphokines in the pathogenesis of human chronic inflammatory and allergic diseases. Immunol. Rev. 123:23.
    • (1991) Immunol. Rev. , vol.123 , pp. 23
    • Peltz, G.1
  • 16
    • 0028043326 scopus 로고
    • Interleukin-12: A cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes
    • Trinchieri, G. 1994. Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes. Blood 84:4408.
    • (1994) Blood , vol.84 , pp. 4408
    • Trinchieri, G.1
  • 17
    • 0024467154 scopus 로고
    • Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes
    • Kobayashi, M., L. Fitz, M. Ryan, R. M. Hewick, S. C. Clark, S. Chan, R. Loudon, F. Sherman, B. Perussia, and G. Trinchieri. 1989. Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes. J. Exp. Med. 170:827.
    • (1989) J. Exp. Med. , vol.170 , pp. 827
    • Kobayashi, M.1    Fitz, L.2    Ryan, M.3    Hewick, R.M.4    Clark, S.C.5    Chan, S.6    Loudon, R.7    Sherman, F.8    Perussia, B.9    Trinchieri, G.10
  • 22
    • 0001141089 scopus 로고
    • Cell sources of natural killer stimulatory factor (NKSF/IL-12) transcripts and subunit expression
    • Wolf, S. F., D. S. Sieburth, B. Perussia, J. Yetz-Adalpe, and A. D'Andrea. 1992. Cell sources of natural killer stimulatory factor (NKSF/IL-12) transcripts and subunit expression. FASEB J. 6:A1335.
    • (1992) FASEB J. , vol.6
    • Wolf, S.F.1    Sieburth, D.S.2    Perussia, B.3    Yetz-Adalpe, J.4    D'Andrea, A.5
  • 25
    • 0027075937 scopus 로고
    • IL-12 augments antigen-dependent proliferation of activated T lymphocytes
    • Bertagnolli, M. M., B.-Y. Lin, D. Young, and S. H. Herrmann. 1992. IL-12 augments antigen-dependent proliferation of activated T lymphocytes. J. Immunol. 149:3778.
    • (1992) J. Immunol. , vol.149 , pp. 3778
    • Bertagnolli, M.M.1    Lin, B.-Y.2    Young, D.3    Herrmann, S.H.4
  • 27
    • 0026520178 scopus 로고
    • Response of human natural killer cells to NK cell stimulatory factor (NKSF): Cytolytic activity and proliferation of NK cells are differentially regulated by NKSF
    • Robertson, M. J., R. J. Soiffer, S. F. Wolf, T. J. Manley, C. Donahue, D. Young, S. H. Hermann, and J. Ritz. 1992. Response of human natural killer cells to NK cell stimulatory factor (NKSF): cytolytic activity and proliferation of NK cells are differentially regulated by NKSF. J. Exp. Med. 175:779.
    • (1992) J. Exp. Med. , vol.175 , pp. 779
    • Robertson, M.J.1    Soiffer, R.J.2    Wolf, S.F.3    Manley, T.J.4    Donahue, C.5    Young, D.6    Hermann, S.H.7    Ritz, J.8
  • 32
    • 0027180648 scopus 로고
    • Interleukin 12 in host defense against microbial pathogens
    • Locksley, R. M. 1993. Interleukin 12 in host defense against microbial pathogens. Proc. Natl. Acad. Sci. USA 90:5879.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 5879
    • Locksley, R.M.1
  • 33
  • 34
    • 0029078676 scopus 로고
    • IL-12 increases resistance of BALB/c mice to Mycobacterium tuberculosis infection
    • Flynn, J. L., M. M. Goldstein, K. J. Triebold, J. Sypek, S. Wolf, and B. R. Bloom. 1995. IL-12 increases resistance of BALB/c mice to Mycobacterium tuberculosis infection. J. Immunol. 155:2515.
    • (1995) J. Immunol. , vol.155 , pp. 2515
    • Flynn, J.L.1    Goldstein, M.M.2    Triebold, K.J.3    Sypek, J.4    Wolf, S.5    Bloom, B.R.6
  • 36
    • 0027530129 scopus 로고
    • Interleukin 12 and tumor necrosis factor α are costimulators of interferon-γ production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist
    • Tripp, C. S., S. F. Wolf, and E. R. Unanue. 1993. Interleukin 12 and tumor necrosis factor α are costimulators of interferon-γ production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist. Proc. Natl. Acad. Sci. USA 90:3725.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 3725
    • Tripp, C.S.1    Wolf, S.F.2    Unanue, E.R.3
  • 37
    • 0025335354 scopus 로고
    • Homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein Barr virus gene BCRFI
    • Moore, K. W., P. Vieira, D. F. Fiorentino, M. L. Trounstine, T. A. Khan, and T. R. Mosmann. 1990. Homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein Barr virus gene BCRFI. Science 248:1230.
    • (1990) Science , vol.248 , pp. 1230
    • Moore, K.W.1    Vieira, P.2    Fiorentino, D.F.3    Trounstine, M.L.4    Khan, T.A.5    Mosmann, T.R.6
  • 38
    • 0026094306 scopus 로고
    • Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: An autoregulatory role of IL-10 produced by monocytes
    • de Waal Malefyt, R., J. Abrams, B. Bennett, C. G. Figdor, and J. E. DeVries. 1991. Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J. Exp. Med. 174:1209.
    • (1991) J. Exp. Med. , vol.174 , pp. 1209
    • De Waal Malefyt, R.1    Abrams, J.2    Bennett, B.3    Figdor, C.G.4    DeVries, J.E.5
  • 39
    • 0025889036 scopus 로고
    • Macrophage deactivation by interleukin 10
    • Bogdon, C., Y. Vodovotz, and C. Nathan. 1991. Macrophage deactivation by interleukin 10. J. Exp. Med. 174:1549.
    • (1991) J. Exp. Med. , vol.174 , pp. 1549
    • Bogdon, C.1    Vodovotz, Y.2    Nathan, C.3
  • 40
    • 0027240219 scopus 로고
    • Interleukin 10 (IL-10) inhibits human lymphocyte interferon-γ production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells
    • D'Andrea, A., M. Aste-Amezaga, N. M. Valiante, X. Ma, M. Kubin, and G. Trinchieri. 1993. Interleukin 10 (IL-10) inhibits human lymphocyte interferon-γ production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells. J. Exp. Med. 178:1041.
    • (1993) J. Exp. Med. , vol.178 , pp. 1041
    • D'Andrea, A.1    Aste-Amezaga, M.2    Valiante, N.M.3    Ma, X.4    Kubin, M.5    Trinchieri, G.6
  • 41
    • 0027260963 scopus 로고
    • Analysis of cytokine mRNA expression during primary granuloma formation induced by eggs of Schistosoma mansoni
    • Wynn, T. A., I. Eltoum, A. W. Cheever, F. A. Lewis, W. C. Gause, and A. Sher. 1993. Analysis of cytokine mRNA expression during primary granuloma formation induced by eggs of Schistosoma mansoni. J. Immunol. 151:1430.
    • (1993) J. Immunol. , vol.151 , pp. 1430
    • Wynn, T.A.1    Eltoum, I.2    Cheever, A.W.3    Lewis, F.A.4    Gause, W.C.5    Sher, A.6
  • 42
    • 0020541599 scopus 로고
    • Spontaneous release of interleukin-2 by lung T lymphocytes in active pulmonary sarcoidosis
    • Pinkston, P., P. B. Bitterman, and R. G. Crystal. 1983. Spontaneous release of interleukin-2 by lung T lymphocytes in active pulmonary sarcoidosis. N. Engl. J. Med. 308:793.
    • (1983) N. Engl. J. Med. , vol.308 , pp. 793
    • Pinkston, P.1    Bitterman, P.B.2    Crystal, R.G.3
  • 43
    • 0021885782 scopus 로고
    • Gamma interferon is spontaneously released by alveolar macrophages and lung T-lymphocytes in patients with pulmonary sarcoidosis
    • Robinson, B. W. S., T. L. McLemore, and R. G. Crystal. 1985. Gamma interferon is spontaneously released by alveolar macrophages and lung T-lymphocytes in patients with pulmonary sarcoidosis. J. Clin. Invest. 75:1488.
    • (1985) J. Clin. Invest. , vol.75 , pp. 1488
    • Robinson, B.W.S.1    McLemore, T.L.2    Crystal, R.G.3
  • 44
    • 0028036941 scopus 로고
    • Activated T cells and cytokines in bronchoalveolar lavages from patients with various lung diseases associated with eosinophilia
    • Walker, C., W. Bauer, R. K. Braun, G. Menz, P. Braun, F. Schwarz, T. T. Hansel, and B. Villiger. 1994. Activated T cells and cytokines in bronchoalveolar lavages from patients with various lung diseases associated with eosinophilia. Am. J. Respir. Crit. Care Med. 150:1038.
    • (1994) Am. J. Respir. Crit. Care Med. , vol.150 , pp. 1038
    • Walker, C.1    Bauer, W.2    Braun, R.K.3    Menz, G.4    Braun, P.5    Schwarz, F.6    Hansel, T.T.7    Villiger, B.8
  • 45
    • 0021288425 scopus 로고
    • Interstitial lung diseases of unknown cause: Disorders characterized by chronic inflammation of the lower respiratory tract
    • Crystal, R. G., P. B. Bitterman, S. Rennard, A. J. Hance, and B. A. Keogh. 1984. Interstitial lung diseases of unknown cause: disorders characterized by chronic inflammation of the lower respiratory tract. N. Engl. J. Med. 310:154.
    • (1984) N. Engl. J. Med. , vol.310 , pp. 154
    • Crystal, R.G.1    Bitterman, P.B.2    Rennard, S.3    Hance, A.J.4    Keogh, B.A.5
  • 46
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156.
    • (1987) Anal. Biochem. , vol.162 , pp. 156
    • Chomczynski, P.1    Sacchi, N.2
  • 49
    • 0025745472 scopus 로고
    • IL-12: Monoclonal antibodies specific for the 40 kDa subunit block receptor binding and biologic activity on activated human lymphoblasts
    • Chizzonite, R., T. Truitt, F. J. Podlaski, A. G. Wolitzky, P. M. Quin, P. Nunes, A. S. Stern, and M. K. Gately. 1990. IL-12: monoclonal antibodies specific for the 40 kDa subunit block receptor binding and biologic activity on activated human lymphoblasts. J. Immunol. 147:1548.
    • (1990) J. Immunol. , vol.147 , pp. 1548
    • Chizzonite, R.1    Truitt, T.2    Podlaski, F.J.3    Wolitzky, A.G.4    Quin, P.M.5    Nunes, P.6    Stern, A.S.7    Gately, M.K.8
  • 50
    • 0026261695 scopus 로고
    • Most human pulmonary infiltrating lymphocytes display the surface immune phenotype and functional responses of sensitized T-cells
    • Marathias, K, P., F. I. Preffer, C. Pinto, and R. L. Kradin. 1991. Most human pulmonary infiltrating lymphocytes display the surface immune phenotype and functional responses of sensitized T-cells. Am. J. Respir. Cell Mol. Biol. 5:470.
    • (1991) Am. J. Respir. Cell Mol. Biol. , vol.5 , pp. 470
    • Marathias, K.P.1    Preffer, F.I.2    Pinto, C.3    Kradin, R.L.4
  • 52
    • 0027409793 scopus 로고
    • Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper 1 (Th1)-specific immune responses and inhibits the development of IL-4 producing Th cells
    • Manetti, R., P. Parronchi, M. G. Giudizi, M. P. Piccinni, E. Maggi, G. Trinchieri, and S. Romagnani. 1993. Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper 1 (Th1)-specific immune responses and inhibits the development of IL-4 producing Th cells. J. Exp. Med. 177:1199.
    • (1993) J. Exp. Med. , vol.177 , pp. 1199
    • Manetti, R.1    Parronchi, P.2    Giudizi, M.G.3    Piccinni, M.P.4    Maggi, E.5    Trinchieri, G.6    Romagnani, S.7
  • 53
    • 0027265784 scopus 로고
    • IL-12 induces the production of IFN-gamma by neonatal human CD4 T cells
    • Wu, C. Y., C. Demeare, M. Kiniwa, M. Gately, and G. Delepesse. 1993. IL-12 induces the production of IFN-gamma by neonatal human CD4 T cells. J. Immunol. 151:1938.
    • (1993) J. Immunol. , vol.151 , pp. 1938
    • Wu, C.Y.1    Demeare, C.2    Kiniwa, M.3    Gately, M.4    Delepesse, G.5
  • 54
  • 57
    • 0021219282 scopus 로고
    • Natural killer cells are present in the normal human lung but are functionally impotent
    • Robinson, B. W. S., P. Pinkston, and R. G. Crystal. 1984. Natural killer cells are present in the normal human lung but are functionally impotent. J. Clin. Invest. 74:942.
    • (1984) J. Clin. Invest. , vol.74 , pp. 942
    • Robinson, B.W.S.1    Pinkston, P.2    Crystal, R.G.3
  • 59
    • 0020541599 scopus 로고
    • Spontaneous release of interleukin-2 by lung T lymphocytes in active pulmonary sarcoidosis
    • Pinkston, P., P. B. Bitterman, and R. G. Crystal. 1983. Spontaneous release of interleukin-2 by lung T lymphocytes in active pulmonary sarcoidosis. N. Engl. J. Med. 308:793.
    • (1983) N. Engl. J. Med. , vol.308 , pp. 793
    • Pinkston, P.1    Bitterman, P.B.2    Crystal, R.G.3
  • 60
    • 0026802079 scopus 로고
    • T-lymphocytes that accumulate in the lung in sarcoidosis have evidence of recent stimulation of the T-cell receptor
    • DuBois, R. M., M. Kirby, B. Balbi, C. Saltini, and R. G. Crystal. 1992. T-lymphocytes that accumulate in the lung in sarcoidosis have evidence of recent stimulation of the T-cell receptor. Am. Rev. Respir. Dis. 145:1205.
    • (1992) Am. Rev. Respir. Dis. , vol.145 , pp. 1205
    • Dubois, R.M.1    Kirby, M.2    Balbi, B.3    Saltini, C.4    Crystal, R.G.5
  • 61
    • 0025296415 scopus 로고
    • Comparison of alveolar macrophages and blood monocytes oxidative burst response in pulmonary sarcoidosis
    • Nielson, H., J. Frederickson, D. Sherson, and N. Milman. 1990. Comparison of alveolar macrophages and blood monocytes oxidative burst response in pulmonary sarcoidosis. APMIS 98:401.
    • (1990) APMIS , vol.98 , pp. 401
    • Nielson, H.1    Frederickson, J.2    Sherson, D.3    Milman, N.4
  • 63
    • 0027417964 scopus 로고
    • Increased secretion of tumor necrosis factor-alpha, interleukin-1-beta, and interleukin-6 by alveolar macrophages from patients with sarcoidosis
    • Steffen, M., J. Petersen, M. Oldigs, A. Karmeier, H. Magnussen, H. G. Thiele, and A. Raedler. 1993. Increased secretion of tumor necrosis factor-alpha, interleukin-1-beta, and interleukin-6 by alveolar macrophages from patients with sarcoidosis. J. Allergy Clin. Immunol. 91:939.
    • (1993) J. Allergy Clin. Immunol. , vol.91 , pp. 939
    • Steffen, M.1    Petersen, J.2    Oldigs, M.3    Karmeier, A.4    Magnussen, H.5    Thiele, H.G.6    Raedler, A.7
  • 66
    • 0028231754 scopus 로고
    • Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology
    • Wynn, T. A., I. Eltoum, I. P. Oswald, A. W. Cheever, and A. Sher. 1994. Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology. J. Exp. Med. 179:1551.
    • (1994) J. Exp. Med. , vol.179 , pp. 1551
    • Wynn, T.A.1    Eltoum, I.2    Oswald, I.P.3    Cheever, A.W.4    Sher, A.5
  • 67
    • 0029112239 scopus 로고
    • In vivo regulation of macrophage IL-12 production during type 1 and type 2 cytokine-mediated granuloma formation
    • Chensue, S. W., J. H. Ruth, K. Warmington, P. Lincoln, and S. L. Kunkel. 1995. In vivo regulation of macrophage IL-12 production during type 1 and type 2 cytokine-mediated granuloma formation. J. Immunol. 155:3546.
    • (1995) J. Immunol. , vol.155 , pp. 3546
    • Chensue, S.W.1    Ruth, J.H.2    Warmington, K.3    Lincoln, P.4    Kunkel, S.L.5
  • 72
    • 0029093933 scopus 로고
    • The role of IL-12 in the induction of organ-specific autoimmune diseases
    • Trembleau, S., T. Germann, M. K. Gately, and L. Adorini. 1995. The role of IL-12 in the induction of organ-specific autoimmune diseases. Immunol Today 16:363.
    • (1995) Immunol Today , vol.16 , pp. 363
    • Trembleau, S.1    Germann, T.2    Gately, M.K.3    Adorini, L.4
  • 73
    • 0028943066 scopus 로고
    • Early interleukin 12 production by macrophages in response to mycobacterial infection depends on interferon γ and tumor necrosis factor α
    • Flesch, I. E. A., J. H. Hess, S. Huang, M. Agnet, J. Rothe, H. Bluethmann, and S. H. E. Kaufmann. 1995. Early interleukin 12 production by macrophages in response to mycobacterial infection depends on interferon γ and tumor necrosis factor α. J. Exp. Med. 181:1615.
    • (1995) J. Exp. Med. , vol.181 , pp. 1615
    • Flesch, I.E.A.1    Hess, J.H.2    Huang, S.3    Agnet, M.4    Rothe, J.5    Bluethmann, H.6    Kaufmann, S.H.E.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.