DNA demethylase expression correlates with lung resistance protein expression in common epithelial ovarian cancers

Journal of International Medical Research

Volumn 29, Issue 3, 2001, Pages 204-213

  Hattori, M ^a   Sakamoto, H ^a   Yamamoto, T ^a  

^a NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

DNA demethylase; Epigenetic control; Gene expression; Lung resistance protein; Ovarian cancer

Indexed keywords

DEOXYRIBONUCLEOPROTEIN; DNA; DNA DEMETHYLASE; LUNG RESISTANCE PROTEIN; UNCLASSIFIED DRUG;

ADENOCARCINOMA; ARTICLE; CANCER STAGING; CANCER SURVIVAL; CONTROLLED STUDY; CORRELATION FUNCTION; ENDOMETRIOID CARCINOMA; EPITHELIUM; FEMALE; GENE EXPRESSION; GENETIC REGULATION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; OVARY CANCER; PROTEIN EXPRESSION;

EID: 0034947098     PISSN: 03000605     EISSN: None     Source Type: Journal    
DOI: 10.1177/147323000102900308     Document Type: Article

References (14)

1. Alterations in DNA methylation: A fundamental aspect of neoplasia
2. Promoter-region hypermethylation and gene silencing in human cancer
3. A mammalian protein with specific demethylase activity for mCpG DNA
4. Molecular biology of multidrug resistance (MDR) in ovarian cancers and novel method of detecting developing MDR in vitro
5. Identification and characterization of a family of mammalian methyl-CpG binding proteins
6. Expression and localization of oxytocin receptor gene in human uterine endometrium in relation to the menstrual cycle
7. DNA demethylase is a processive enzyme
8. Hypermethylation in the retinoblastoma gene is associated with unilateral, sporadic retinoblastoma
9. Cytosine methylation transforms an E2F site in the retinoblastoma gene promoter into a binding site for the general repressor methylcytosine-binding protein 2 (MeCP2)
10. Methylation of estrogen and progesterone receptor gene 5′ CpG islands correlates with lack of estrogen and progesterone receptor gene expression in breast tumors
11. Examination of the DNA methylation properties in nontumorigenic and tumorigenic breast epithelial cell lines
12. Methylation of the androgen receptor promoter CpG island is associated with loss of androgen receptor expression in prostate cancer cells
13. DNA demethylase is expressed in ovarian cancers and the expression correlates with demethylation of CpG site in the promoter region of c-erbB-2 and survivin gene
14. Drug resistance-associated marker Lrp for prediction of response to chemotherapy and prognoses in advanced ovarian carcinoma