Molecular biology of multidrug resistance (MDR) in ovarian cancers and novel method of detecting developing MDR in vitro

Acta Obstetrica et Gynaecologica Japonica

Volumn 51, Issue 8, 1999, Pages 549-561

  Sakamoto, Hideki ^a  

^a NIHON UNIVERSITY   (Japan)

Author keywords

c erbB 2; Multidrug resistance; Ovarian cancer; Survivin

Indexed keywords

CISPLATIN; DNA; GLUTATHIONE; GLUTATHIONE TRANSFERASE; LUNG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN; ONCOPROTEIN; PROTEIN BCL 2; PROTEIN P53; SURVIVIN; TUMOR MARKER; UNCLASSIFIED DRUG;

CANCER CHEMOTHERAPY; CONFERENCE PAPER; CONTROLLED STUDY; DNA REPAIR; DRUG TRANSPORT; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IN VITRO STUDY; MAJOR CLINICAL STUDY; MICROSATELLITE INSTABILITY; MOLECULAR BIOLOGY; MULTIDRUG RESISTANCE; OVARY CANCER; PHENOTYPE; TELOMERE;

EID: 0032852611     PISSN: 03009165     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (9)

1. Sakamoto H, et al. Gene expression in primary, metastatic and recurrent lesions of endometrial cancer. Obstet Gynecol Invest 1999 ; in press
2. Sood AK, et al. Genomic instability in ovarian cancer : a reassessment using an arbitrarily primed polymerase chain reaction. Oncogene 1996 ; 13 : 2499-2504
3. Isquierdo, et al. Drugresistance-associated marker Lrp for prediction of response to chemotherapy and prognosis in advanced ovarian carcinoma. J National Cancer Insititute 1995 ; 87 : 1230-1237
4. Kavallaris M, et al . MDR-1 and multidrug resistance-associated protein (MRP) gene expression in epithelial ovarian tumors. Cancer Letters 1996 ; 102 : 7-16
5. Ambrosisni G, et al. A novel antiapoptosis gene, survivin is expressed in cancers and lymphoma. Nature Medicine 1997 ; 3 : 917-921
6. Scheffer GL, et al . The drug resistance-related protein LRP is the humam major vault protein. Nature Medicine 1995 ; 1 : 578-582
7. Murase M, et al. Expression of MRP and mdr1 in human gastrointestinal cancer cell lines : A correlation with resistance against doxorubicin. J Surgical Oncol 1996 ; 61 : 223-239
8. Breuninger LM, et al. Expression of multidrug resistance-associated protein in NIH/3T3 cells confers miltirug resistance associated with increased drug efflux and altered intracellular drug distribution. Cancer Research 1995 ; 55 : 5342-5347
9. Izquierdo MA, et al. Overlapping phenotypes of multidrug resistance among panels of human cancer cell lines. Int J Cancer 1996 ; 65 : 230-237