Comparison of twice- and three times daily tiagabine for the adjunctive treatment of partial seizures in refractory patients with epilepsy: An open label, randomised, parallel-group study

Epileptic Disorders

Volumn 3, Issue 2, 2001, Pages 91-100

  Biraben, A ^a   Beaussart, M ^a   Josien, E ^a   Pestre, M ^a   Savet, J F ^a   Schaff, J L ^a   Tourniaire, D ^a   Sevestre, M ^a   Renault Djouadi, J ^a  

^a SANOFI   (France)

Author keywords

Dosing regimen; Partial seizure; Refractory epilepsy; Tiagabine; Titration

Indexed keywords

TIAGABINE;

ADD ON THERAPY; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DOSE RESPONSE; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; EPILEPSY; HUMAN; MAJOR CLINICAL STUDY; NEUROTOXICITY; PHARYNGITIS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; VISUAL FIELD DEFECT;

ADOLESCENT; ADULT; AGED; ANTICONVULSANTS; CHILD; DRUG ADMINISTRATION SCHEDULE; DRUG THERAPY, COMBINATION; EPILEPSIES, PARTIAL; FEMALE; HUMANS; MALE; MIDDLE AGED; NIPECOTIC ACIDS; TREATMENT OUTCOME;

EID: 0034943853     PISSN: 12949361     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Tiagabine (Drug Profile)
2. Epidemiology of the epilepsies
3. New antiepileptic drugs
4. The new antiepileptic drugs: Systematic review or their efficacy and tolerability
5. A review of the preclinical pharmacology of tiagabine: A potent and selective anticonvulsant GABA uptake inhibitor
6. Antiepileptic drug therapy: General treatment principles and application for special patient populations
7. Tiagabine in the management of epilepsy
8. Pharmacokinetics of tiagabine, a gamma-aminobutyric acid-uptake inhibitor in healthy subjects after single and multiple doses
9. Pharmacokinetics of tiagabine as add-on therapy in patients taking enzyme-inducing antiepilepsy drugs
10. International experience with tiagabine add-on therapy
11. Tiagabine: The safety landscape
12. Neuropsychological effects of tiagabine, a potential new antiepileptic drug
13. Long-term cognitive and EEG effects of tiagabine in drug resistant partial epilepsy
14. Review of controlled trials of Gabitril (tiagabine): A clinician's viewpoint
15. Proposal for revised clinical and electroencephalographic classification of epileptic seizures
16. Tiagabine: A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the management of epilepsy
17. Topiramate placebo-controlled dose-ranging trial in refractory partial epilepsy using 200-, 400-, and 600-mg daily dosages
18. Zonisamide for add-on treatment of refractory partial epilepsy: A European double-blind trial
19. Gabapentin (Neurontin) as add-on therapy in patients with partial seizures; a double-blind, placebo-controlled study
20. Efficacy and safety of add-on divalproex sodium in the treatment of complex partial seizures
21. Placebo-controlled study of the efficacy and safety of lamotrigine in patients with partial seizures
22. Tiagabine in the treatment of epilepsy - A clinical review with a guide for the prescribing physician