Regulation of hemangioblast development

Annals of the New York Academy of Sciences

Volumn 938, Issue , 2001, Pages 96-108

  Lacaud, Georges ^a   Robertson, Scott ^b   Palis, James ^c   Kennedy, Marion ^a   Keller, Gordon ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

^c UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Embryonic stem cells; Hemangioblast; Runx1; scl tal 1

Indexed keywords

GENE PRODUCT; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RUNX1; TRANSCRIPTION FACTOR SCL; TRANSCRIPTION FACTOR TAL 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; CELL DIFFERENTIATION; CONFERENCE PAPER; EMBRYO; EMBRYO DEVELOPMENT; ENDOTHELIUM CELL; HEMANGIOBLAST; HEMATOPOIETIC STEM CELL; MOLECULAR MODEL; MOUSE; NONHUMAN; STEM CELL; TRANSCRIPTION REGULATION;

EID: 0034943046     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2001.tb03578.x     Document Type: Conference Paper

References (68)

1. A phase and electron microscopic study of vasculogenesis and erythropoiesis in the yolk sac of the mouse
2. Hereditary anemias of the mouse: A review for geneticists
3. Development of the mouse hematopoietic system I. Types of hemoglobin produced in embryonic yolk sac and liver
4. Hemoglobin ontogeny during normal mouse fetal development
5. Ontogeny of the hematopoietic system: Yolk sac origin of in vivo and in vitro colony forming cells in the developing mouse embryo
6. Haemopoietic cells
7. Properties of the earliest clonogenic hemopoietic precursor to appear in the developing murine yolk sac
8. Emergence of multipotent hemopoietic cells in the yolk sac and paraaortic splanchnopleura in mouse embryos, beginning at 8.5 days postcoitus
9. Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac
10. Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse
11. Stem cell migration in developing myeloid and lymphoid systems
12. On the origin of haemopoietic stem cells in the avian embryo: An experimental approach
13. An early pre-liver intra-embryonic source of CFU-S in the developing mouse
14. Development of hematopoietic stem cell activity in the mouse embryo
15. Studies on the origin of blood vessels and of red corpuscles as seen in the living blastoderm of the chick during the second day of incubation
16. The sialomucin CD34 is expressed on hematopoietic cells and blood vessels during murine development
17. The SCL/Tal-1 gene is expressed in progenitors of both the hematopoietic and vascular systems during embryogenesis
18. PECAM-1: Its expression and function as a cell adhesion molecule on hemopoietic and endothelial cells
19. High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculo-genesis and angiogenesis
20. Ligand-dependent development of the endothelial and hemopoietic lineages from embryonic mesodermal cells expressing vascular endothelial growth factor receptor 2
21. Flk-1 expression defines a population of early embryonic hematopoietic precursors
22. Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
23. Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene
24. Absence of blood formation in mice lacking the T-cell leukemia oncoprotein tal-1/SCL
25. Cloche, an early acting zebrafish gene, is required by both the endothelial and hematopoietic lineages
26. The in vitro development of blastocyst-derived embryonic stem cell lines: Formation of visceral yolk sac, blood islands and myocardium
27. In vitro differentiation of embryonic stem cells
28. Hematopoietic development of embryonic stem cells in vitro: Cytokine and receptor gene expression
29. Early fetal hematopoietic development from in vitro differentiated embryonic stem cells
30. Hematopoietic commitment during embryonic stem cell differentiation in culture
31. A transitional stage in the commitment of mesoderm to hematopoiesis requiring the transcription factor SCL/tal-1
32. Initiation of murine embryonic erythropoiesis: A spatial analysis
33. - embryonic stem cells
34. An early haematopoietic defect in mice lacking the transcription factor GATA-2
35. The T cell leukemia oncoprotein SCL/tal-1 is essential for development of all hematopoietlc lineages
36. A common precursor for primitive erythropoiesis and definitive haematopoiesis
37. A common precursor for hematopoietic and endothelial cells
38. Progressive lineage analysis by cell sorting and culture identifies FLKl+VE-cadherin+ cells at a diverging point of endothelial and hemopoietic lineages
39. Basic fibroblast growth factor positively regulates hematopoietic development
40. Chromosomal translocation in a human leukemic stem-cell line disrupts the T-cell antigen receptor delta-chain diversity region and results in a previously unreported fusion transcript
41. The gene SCL is expressed during early hematopoiesis and encodes a differentiation-related DNA-binding motif
42. The tal gene undergoes chromosome translocation in T cell leukemia and potentially encodes a helix-loop-helix protein
43. SCL is coexpressed with GATA-1 in hemopoietic cells but is also expressed in developing brain
44. βHLH factors in muscle development: Dead lines and commitments, what to leave in and what to leave out
45. Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix- loop-helix protein
46. The gene SCL is expressed during early hematopoiesis and encodes a differentiation-related DNA-binding motif
47. Differential expression of the LYL, SCL and E2A helix-loop-helix genes within the hemopoietic system
48. Expression of tal-1 and GATA-binding proteins during human hematopoiesis
49. Unsuspected role for the T-cell leukemia protein SCL/tal-1 in vascular development
50. The SCL gene specifies haemangioblast development from early mesoderm
51. SCL/tal-1 transcription factor acts downstream of cloche to specify hematopoietic and vascular progenitors in zebrafish
52. t(8,21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene
53. Role of the transcription factor AML-1 in acute leukemia and hematopoietic differentiation
54. Alterations of the AML1 transcription factor in human leukemia
55. A new transcription factor family associated with human leukemia
56. The segmentation gene runt is needed to activate Sex-lethal, a gene that controls sex determination and dosage compensation in Drosophila
57. The localized requirements for a gene affecting segmentation in Drosophila: Analysis of larvae mosaic for runt
58. Expression and function of the Drosophila gene runt in early stages of neural development
59. Patterning of cells in the Drosophila eye by Lozenge, which shares homologous domains with AML1
60. Specification of Drosophila hematopoietic lineage by conserved transcription factors
61. Purification of core-binding factor, a protein that binds the conserved core site in murine leukemia virus enhancers
62. Isolation of PEBP2 alpha B cDNA representing the mouse homolog of human acute myeloid leukemia gene, AML1
63. Molecular cloning and characterization of PEBP2 beta, the heterodimeric partner of a novel Drosophila runt-related DNA binding protein PEBP2 alpha
64. AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis
65. Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis
66. Cbfa2 is required for the formation of intra-aortic hematopoietic clusters
67. A Xenopus homologue of aml-1 reveals unexpected patterning mechanisms leading to the formation of embryonic blood
68. Failure of embryonic hematopoiesis and lethal hemorrhages in mouse embryos heterozygous for a knocked-in leukemia gene CBFB-MYH11