메뉴 건너뛰기




Volumn 15, Issue 2, 2001, Pages 85-95

Tyrosine kinase inhibitors in the treatment of chronic myeloid leukaemia: So far so good?

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; GLYCOPROTEIN P; HERBIMYCIN A; IMATINIB; PROTEIN INHIBITOR; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR;

EID: 0034942219     PISSN: 0268960X     EISSN: None     Source Type: Journal    
DOI: 10.1054/blre.2001.0152     Document Type: Article
Times cited : (23)

References (126)
  • 2
    • 0015694748 scopus 로고
    • A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining
    • (1973) Nature , vol.243 , pp. 290-293
    • Rowley, J.D.1
  • 9
    • 0024343691 scopus 로고
    • N-terminal mutations activate the leukemogenic potential of the myristoylated form of c-abl
    • (1989) EMBO J , vol.8 , pp. 449-456
    • Jackson, P.1    Baltimore, D.2
  • 11
    • 0034634597 scopus 로고    scopus 로고
    • c-Abl has high intrinsic tyrosine kinase activity that is stimulated by mutation of the Src homology of 3 domain and by autophosphorylation at two distinct regulatory tyrosines
    • (2000) J Biol Chem , vol.275 , pp. 35631-35637
    • Brasher, B.B.1    Van Etten, R.A.2
  • 12
    • 0027536793 scopus 로고
    • An actin-binding function contributes to transformation by the Bcr-Abl oncoprotein of Philadelphia chromosome-positive human leukemias
    • (1993) EMBO J , vol.12 , pp. 1533-1546
    • McWhirter, J.R.1    Wang, J.Y.2
  • 14
    • 0029879676 scopus 로고    scopus 로고
    • The cytostatic function of c-Abl is controlled by multiple nuclear localization signals and requires the p53 and Rb tumor suppressor gene products
    • (1996) EMBO J , vol.15 , pp. 1583-1595
    • Wen, S.T.1    Jackson, P.K.2    Van Etten, R.A.3
  • 15
    • 0024353722 scopus 로고
    • The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization
    • (1989) Cell , vol.58 , pp. 669-678
    • Van Etten, R.A.1    Jackson, P.2    Baltimore, D.3
  • 19
    • 0027429964 scopus 로고
    • A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-abl tyrosine kinase in the cell cycle
    • (1993) Cell , vol.75 , pp. 779-790
    • Welch, P.J.1    Wang, J.Y.2
  • 20
    • 0029093830 scopus 로고
    • Abrogation of retinoblastoma protein function by c-Abl through tyrosine kinase-dependent and -independent mechanisms
    • (1995) Mol Cell Biol , vol.15 , pp. 5542-5551
    • Welch, P.J.1    Wang, J.Y.2
  • 35
    • 0029816460 scopus 로고    scopus 로고
    • The diversity of BCR-ABL fusion proteins and their relationship to leukemia phenotype
    • (1996) Blood , vol.88 , pp. 2375-2384
    • Melo, J.1
  • 38
    • 10144254429 scopus 로고    scopus 로고
    • Neutrophilic-chronic myeloid leukemia: A distinct disease with a specific molecular marker (BCR/ABL with C3/A2 junction)
    • (1996) Blood , vol.88 , pp. 2410-2414
    • Pane, F.1    Frigeri, F.2    Sindona, M.3
  • 45
    • 0035014278 scopus 로고    scopus 로고
    • Recent advances in the molecular and cellular biology of CML: Lessons to be learned from the laboratory
    • In Press
    • (2001) Br J Haematol
    • Holyoake, T.1
  • 55
    • 0032533620 scopus 로고    scopus 로고
    • BCR-ABL efficiently induces a myeloproliferative disease and production of excess interleukin-3 and granulocyte-macrophage colony-stimulating factor in mice: A novel model for chronic myelogenous leukemia
    • (1998) Blood , vol.92 , pp. 3829-3840
    • Zhang, X.1    Ren, R.2
  • 56
    • 0032533257 scopus 로고    scopus 로고
    • Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving a P210 bcr/abl-transduced bone marrow
    • (1998) Blood , vol.92 , pp. 3780-3792
    • Pear, W.S.1    Miller, J.P.2    Xu, L.3
  • 63
    • 0026458235 scopus 로고
    • Tyrphostins: Tyrosine kinase blockers as novel antiproliferative agents and dissectors of signal transduction
    • (1992) FASEB J , vol.6 , pp. 3275-3282
    • Levitzki, A.1
  • 65
    • 0031752846 scopus 로고    scopus 로고
    • Tyrphostin AG957, a tyrosine kinase inhibitor with anti-BCR/ABL tyrosine kinase activity restores beta I integrin-mediated adhesion and inhibitory signaling in chronic myelogenous leukaemia hematopoietic progenitors
    • (1998) Leukemia , vol.12 , pp. 1708-1717
    • Bhatia, R.1    Munthe, H.A.2    Verfaillie, C.M.3
  • 70
    • 0026746308 scopus 로고
    • Effect of herbimycin A, an antagonist of tyrosine kinase, on bcr/abl oncoprotein-associated cell proliferations: Abrogative effect on the transformation of murine hematopoietic cells by transfection of a retroviral vector expressing oncoprotein P210 bcr/abl and preferential inhibition on Ph-I-positive leukemia cell growth
    • (1992) Blood , vol.80 , pp. 1330-1338
    • Okabe, M.1    Uehara, Y.2    Miyagishima, T.3
  • 73
    • 10244255276 scopus 로고    scopus 로고
    • Selection of myeloid progenitors lacking BCR-ABL mRNA in chronic myelogenous leukemia patients after in-vitro treatment with the tyrosine kinase inhibitor genistein
    • (1996) Blood , vol.88 , pp. 3091-3100
    • Carlo-Stella, C.1    Dotti, G.2    Mangoni, L.3
  • 79
    • 0024383718 scopus 로고
    • Platelet-derived growth factor
    • (1989) Lancet , vol.1 , pp. 1179-1182
    • Ross, R.1
  • 85
    • 0034689031 scopus 로고    scopus 로고
    • Blockade of the BCR-ABL kinase activity induces apoptosis of chronic myelogenous leukemia cells by suppressing signal transducer and activator of transcription 5-dependent expression of BCL-xL
    • (2000) J Exp Med , vol.191 , pp. 977-984
    • Horita, M.1    Andreu, E.J.2    Benito, A.3
  • 87
    • 0029131231 scopus 로고
    • BCR-ABL-mediated inhibition of apoptosis with delay of G2/M transition after DNA damage: A mechanism of resistance to multiple anticancer agents
    • (1995) Blood , vol.86 , pp. 1148-1158
    • Bedi, A.1    Barber, J.2    Bedi, G.3
  • 88
    • 0034665903 scopus 로고    scopus 로고
    • CGP57148B (ST1571) induces differentiation and apoptosis and sensitizes Bcr-Abl-positive human leukemia cells to apoptosis due to antileukemic drugs
    • (2000) Blood , vol.96 , pp. 2246-2253
    • Fang, G.1    Kim, C.N.2    Perkins, C.L.3
  • 91
    • 0031454003 scopus 로고    scopus 로고
    • CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins
    • (1997) Blood , vol.90 , pp. 4947-4952
    • Carroll, M.1    Ohno-Jones, S.2    Tamura, S.3
  • 101
  • 106
    • 0001338423 scopus 로고    scopus 로고
    • Phase II study of ST1571, a tyrosine kinase inhibitor, in patients with resistant or refractory Philadelphia chromosome-positive chronic myeloid leukemia
    • Abstr 2022
    • (2000) Blood , vol.96
    • Kanterjian, H.1    Sawyers, C.L.2    Hochhaus, A.3
  • 107
    • 0001566710 scopus 로고    scopus 로고
    • A Phase II study of ST1571 in adult patients with Philadelphia chromosome positive chronic myeloid leukemia in accelerated phase
    • Abstr 2021
    • (2000) Blood , vol.96
    • Talpaz, M.1    Silver, R.T.2    Druker, B.J.3
  • 109
    • 0000348652 scopus 로고    scopus 로고
    • A Phase II study to determine the safety and anti-leukaemic effects of ST1571 in adult patients with Philadelphia chromosome positive acute leukemias
    • Abstr 3580
    • (2000) Blood , vol.96
    • Ottmann, O.G.1    Sawyers, C.L.2    Druker, B.J.3
  • 110
    • 85112374881 scopus 로고    scopus 로고
    • Value of interphase fluorescent in-situ hybridisation (iFISH) studies in monitoring response to ST1571 therapy in patients with Philadelphia chromosome positive chronic myelogenous leukemia
    • Abstr 4833
    • (2000) Blood , vol.96
    • Kanterjian, H.1    O'Brien, S.2    Hayes, K.J.3
  • 111
    • 0004622138 scopus 로고    scopus 로고
    • PCR-negative molecular remissions in chronic-accelerated-, and blast crisis-phase CML patients treated with ST1571, an ABL-specific kinase inhibitor
    • Abstr 2026
    • (2000) Blood , vol.96
    • Shah, N.P.1    Snyder, D.S.2    Nicoll, J.M.3
  • 112
    • 0003276302 scopus 로고    scopus 로고
    • Monitoring the response of CML patients treated with ST1571 by molecular cytogenetics and quantitative RT-PCR
    • Abstr 3174
    • (2000) Blood , vol.96
    • Paschka, P.1    Schoch, C.2    Lahaye, T.3
  • 113
    • 0034210577 scopus 로고    scopus 로고
    • Mechanism of resistance to the ABL tyrosine kinase inhibitor ST1571 in BCR/ABL -transformed hematopoietic cell lines
    • (2000) Blood , vol.95 , pp. 3498-3505
    • Weisberg, E.1    Griffin, J.D.2
  • 114
    • 0034254368 scopus 로고    scopus 로고
    • Selection and characterisation of BCR-ABL positive cell lines with differential sensitivity to the tyrosine kinase inhibitor ST1571: Diverse mechanisms of resistance
    • (2000) Blood , vol.96 , pp. 1070-1079
    • Mahon, F.X.1    Deininger, M.W.2    Schultheis, B.3
  • 115
    • 0001338426 scopus 로고    scopus 로고
    • Relapse in Ph+ leukemia patients treated with an Abl-specific kinase inhibitor is associated with reactivation of Bcr-Abl
    • Abstr 2024
    • (2000) Blood , vol.96
    • Gorre, M.E.1    Banks, K.2    Hsu, N.C.3
  • 116
    • 0002342285 scopus 로고    scopus 로고
    • BCR/ABL gene amplification: A possible mechanism of drug resistance in patients treated with an abl-specific kinase inhibitor
    • Abstr 1486
    • (2000) Blood , vol.96
    • Mohammed, M.1    Shin, S.2    Deng, S.3
  • 122
    • 0035313251 scopus 로고    scopus 로고
    • In vitro cytotoxic effects of a tyrosine kinase inhibitor ST1571 in combination with commonly used antileukemic agents
    • (2001) Blood , vol.97 , pp. 1999-2007
    • Kano, Y.1    Akutsu, Y.2    Tsunoda, S.3
  • 124
    • 0035282901 scopus 로고    scopus 로고
    • Activity of the farnesyl protein transferase inhibitor SCH66336 against BCR/ABL-induced murine leukemia and primary cells from patients with chronic myeloid leukemia
    • (2001) Blood , vol.97 , pp. 1404-1412
    • Peters, D.G.1    Hoover, R.R.2    Gerlach, M.J.3
  • 125
    • 0035313531 scopus 로고    scopus 로고
    • Comparison of effects of the tyrosine kinase inhibitors AG957, AG490 and ST1571 on BCR-ABL-expressing cells, demonstrating synergy between AG490 and ST1571
    • (2001) Blood , vol.97 , pp. 2008-2015
    • Sun, X.1    Layton, J.E.2    Elefanty, A.3    Lieschke, G.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.