Tumor necrosis factor α activates the phosphorylation of ERK, SAPK/JNK, and p38 kinase in primary cultures of neurons

Neurochemical Research

Volumn 26, Issue 2, 2001, Pages 107-112

  Barbin, G ^a   Roisin, M P ^b   Zalc, B ^a  

^a INSERM   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Cytokines; MAP kinase; Neurons; Phosphorylation; TNF

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CYTOKINE; MITOGEN ACTIVATED PROTEIN KINASE; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; STRESS ACTIVATED PROTEIN KINASE; TRICYCLO[4.3.0.1]DECAN 9 YL XANTHOGENATE;

ANIMAL CELL; ARTICLE; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEMALE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ANIMALS; CELLS, CULTURED; ENZYME INHIBITORS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; NEURONS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RATS; RATS, WISTAR; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0034940205     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011086426652     Document Type: Article

References (40)

1. Apoptosis by death factor
2. Tumor necrosis factor receptor-mediated signaling pathways
3. Two tumour necrosis factor receptors: Structure and function
4. Modulation of life and death by the TNF receptor superfamily
5. The role of sphingolipids in the process of signal transduction
6. Signalling sphingomyelinases: Which, where, how and why?
7. Tumor necrosis factor (TNF)-mediated kinase cascades: Bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2
8. Activation of p38mapk, MKK3, and MKK4 by TNF-alpha in mouse bone marrow-derived macrophages
9. MAP kinase pathways
10. Effects of interleukin-1 and tumor necrosis factor-alpha on astrocytes, microglia, oligodendrocytes, and glial precursors in vitro
11. Tumor necrosis factor identified in multiple sclerosis brain
12. Tumor necrosis factor-alpha expression in ischemic neurons
13. Localization of TNFα and IL-1α immunoreactivities in striatal neurons after surgical injury to the hippocampus
14. Neurotoxic effects of tumor necrosis factor alpha in primary human neuronal cultures are mediated by activation of the glutamate AMPA receptor subtype: Implications for AIDS neuropathogenesis
15. Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis
16. Differential susceptibility of human CNS-derived cell populations to TNF-dependent and independent immune-mediated injury
17. Tumor necrosis factor-alpha: Specific binding sites in rodent brain and pituitary gland
18. Major histocompatibility complex (MHC) class I gene expression in single neurons of the central nervous system: Differential regulation by interferon (IFN)-gamma and tumor necrosis factor (TNF)-alpha
19. Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors
20. Tumor necrosis factor enhancement of transient outward potassium currents in cultured rat cortical neurons
21. The transcription factor NF-kappaB mediates increases in calcium currents and decreases in NMDA- and AMPA/kainate-induced currents induced by tumor necrosis factor-alpha in hippocampal neurons
22. Anti-death properties of TNF against metabolic poisoning: Mitochondrial stabilization by MnSOD
23. Tumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxicity: Evidence for involvement of a kappa B-binding factor and attenuation of peroxide and Ca2+ accumulation
24. Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NFkappaB activation in primary hippocampal neurons
25. Brain astrocytes express region-specific surface glycoproteins in culture
26. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
27. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
28. Molecular cloning and expression of human and rat tumor necrosis factor receptor chain (p60) and its soluble derivative, tumor necrosis factor-binding protein
29. Serum-free B27/neurobasal medium supports differentiated growth of neurons from the striatum, substantia nigra, septum, cerebral cortex, cerebellum, and dentate gyrus
30. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vitro and in vivo
31. TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown
32. Ras signaling in tumor necrosis factor-induced apoptosis
33. Identification of Grb2 as a novel binding partner of tumor necrosis factor TNF receptor I
34. Distinct adapter proteins mediate acid versus neutral sphingomyelinase activation through the p55 receptor for tumor necrosis factor
35. Stress signals for apoptosis: Ceramide and c-Jun kinase
36. Induction of stress-activated protein kinases/c-Jun N-terminal kinases by the p55 tumour necrosis factor receptor does not require sphingomyelinases
37. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
38. Fibroblast growth factors stimulate protein tyrosine phosphorylation and mitogen-activated protein kinase activity in primary cultures of hippocampal neurons
39. TNF-alpha bifunctionally induces proliferation in primary hepatocytes: Role of cell anchorage and spreading
40. Conversion of TNF alpha from antiproliferative to proliferative ligand in mouse intestinal epithelial cells by regulating mitogen-activated protein kinase