Molecular aspects of phosphate homeostasis in mammals;Aspects moléculaires de l'homéostasie du phosphate chez les mammifères

Nephrologie

Volumn 22, Issue 4, 2001, Pages 149-159

  Beck, L ^a   Silve, C ^a  

^a INSERM   (France)

Author keywords

FGF23; Homeostasis; Hypophosphatemia; Npt2; PHEX; Phosphate

Indexed keywords

CARRIER PROTEIN;

BONE; DIETARY INTAKE; HOMEOSTASIS; HORMONAL REGULATION; HUMAN; INTESTINE; KIDNEY; KIDNEY TUBULE ABSORPTION; PHOSPHATE METABOLISM; PHOSPHATE TRANSPORT; REVIEW; VITAMIN D RESISTANT RICKETS;

ABSORPTION; ANIMALS; BIOLOGICAL TRANSPORT; BONE AND BONES; CARRIER PROTEINS; DIET; HOMEOSTASIS; HUMANS; HYPOPHOSPHATEMIA; INTESTINES; KIDNEY; PHOSPHATES; SODIUM-PHOSPHATE COTRANSPORTER PROTEINS; SYMPORTERS;

EID: 0034934050     PISSN: 02504960     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (76)

1. Renal regulation of phosphate excretion
2. Cloning and expression of cDNA for a Na/Pi cotransport system of kidney cortex
3. Characterization of the 5′ flanking region of the human NPT-1 Na+/phosphate cotransporter gene
4. Localization of NaPi-1, a Na/Pi cotransporter, in rabbit kidney proximal tubules. II. Localization by immunohistochemistry
5. Localization of NaPi-1, a Na-Pi cotransporter, in rabbit kidney proximal tubules. I. mRNA localization by reverse transcription/polymerase chain reaction
6. Expression of a renal type I sodium/phosphate transporter (NaPi-1) induces a conductance in Xenopus oocytes permeable for organic and inorganic anions
7. Chloride conductance and Pi transport are separate functions induced by the expression of NaPi-1 in Xenopus oocytes
8. Hepatic sinusoidal membrane transport of anionic drugs mediated by anion transporter Npt1
9. Regulation of ion transport by protein-protein interaction domains
10. Expression cloning of human and rat renal cortex Na/Pi cotransport
11. Characterization of a murine type II sodium-phosphate cotransporter expressed in mammalian small intestine
12. Proximal tubular phosphate reabsorption: Molecular mechanisms
13. Molecular characteristics of phosphate transporters and their regulation
14. Molecular mechanisms of mammalian inorganic phosphate homeostasis
15. Expression of Na-P(i) cotransport in rat kidney: Localization by RT-PCR and immunohistochemistry
16. Regulation of sodium-dependent phosphate transport in osteoclasts
17. +-dependent inorganic phosphate cotransporter (NaPi-2) in rat brain
18. +- dependent phosphate cotransporter (NaPi-2) in rat kidney
19. +/Pi cotransporter is a monomer
20. +-Pi) transporter (SLC34A2)
21. Cloning and functional characterization of a sodium-dependent phosphate transporter expressed in human lung and small intestine
22. Requirement of a leucine residue for (apical) membrane expression of type IIb NaPi cotransporters
23. Expression of type II Na-P(i) cotransporter in alveolar type II cells
24. Cell-surface receptors for gibbon ape leukemia virus and amphotropic murine retrovirus are inducible sodium-dependent phosphate symporters
25. Characterization of the human Glvr-1 phosphate transporter/retrovirus receptor gene and promoter region
26. Molecular cloning and hormonal regulation of PiT-1, a sodium-dependent phosphate cotransporter from rat parathyroid glands
27. Regulation of PiT-1, a sodium-dependent phosphate co-transporter in rat parathyroid glands
28. +)-dependent inorganic phosphate cotransporter
29. Identification of a cDNA/protein leading to an increased Pi-uptake in Xenopus laevis oocytes
30. Identification of a new gene product (diphor-1) regulated by dietary phosphate
31. PDZ domains: Fundamental building blocks in the organization of protein complexes at the plasma membrane
32. Protein-protein interaction pattern of the renal type IIa Na/Pi-cotranspoter
33. PiUS (Pi uptake stimulator) is an inositol hexakisphosphate kinase
34. +-phosphate cotransporter genes in murine kidney
35. +-phosphate cotransport in mouse distal convoluted tubule cells: Evidence for Glvr-1 and Ram-1 gene expression
36. Renal tubular phosphate transport: Cellular mechanisms
37. Post-transcriptional regulation of the proximal tubule NaPi-II transporter in response to PTH and dietary P(i)
38. Parathyroid hormone and dietary phosphate provoke a lysosomal routing of the proximal tubular Na/Pi-cotransporter type II
39. Molecular regulation of renal phosphate transport
40. +-dependent inorganic phosphate transporters by 1,25-dihydroxyvitamin D3. Identification of a vitamin D- responsive element in the human NAPi-3 gene
41. Gene structure and functional analysis of the human Na+/phosphate co-transporter
42. Targeted inactivation of Npt2 in mice leads to severe renal phosphate wasting, hypercalciuria, and skeletal abnormalities
43. +)/phosphate cotransport and cotransporter gene expression
44. Mechanism of phosphate transport adaptation in rat intestinal and renal brush border membranes
45. Phosphate transport adaptation in rat jejunum and plasma level of 1,25-dihydroxyvitamin D3
46. Inorganic phosphate absorption in small intestine
47. Regulation of small intestinal Na-P(i) type IIb cotransporter by dietary phosphate intake
48. +-dependent phosphate co-transporters by a low-phosphate diet and 1,25-dihydroxyvitamin D3
49. Characteristics and regulation of Pi transport in osteogenic cells for bone metabolism
50. Expression of a newly identified phosphate transporter/retrovirus receptor in human SaOS-2 osteoblast-like cells and its regulation by insulin-like growth factor I
51. In vivo expression of transcripts encoding the Glvr-1 phosphate transporter/retrovirus receptor during bone development
52. Phosphate transport in osteoclasts: Functional and immunochemical characterization
53. Hypophosphatémies d'origine génétique
54. Hypo-hyperphosphataemia
55. The molecular basis of hypophosphatemic rickets
56. New insights into the pathogenesis of inherited phosphate wasting disorders
57. Inherited phosphate wasting disorders
58. A gene (PEX) with homologies to endopeptidases is mutated in patients with X-linked hypophosphatemic rickets
59. PHEXdb, a locus-specific database for mutations causing X-linked hypophosphatemia
60. Genomic organization of the human PEX gene mutated in X-linked dominant hypophosphatemic rickets
61. Cloning of human PEX cDNA. Expression, subcellular localization, and endopeptidase activity
62. Pex/PEX tissue distribution and evidence for a deletion in the 3′ region of the Pex gene in X-linked hypophosphatemic mice
63. cDNA cloning of the murine Pex gene implicated in X-linked hypophosphatemia and evidence for expression in bone
64. Pex gene deletions in Gy and Hyp mice provide mouse models for X-linked hypophosphatemia
65. Partial deletion of both the spermine synthase gene and the Pex gene in the X-linked hypophosphatemic, gyro (Gy) mouse
66. PHEX gene and hypophosphatemia
67. Tumor-induced osteomalacia-unveiling a new hormone
68. Brief report: Inhibition of renal phosphate transport by a tumor product in a patient with oncogenic osteomalacia
69. Autosomal dominant hypophosphatemic rickets/osteomalacia: Clinical characterization of a novel renal phosphate-wasting disorder
70. Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23
71. Identification of a novel fibroblast growth factor, FGF-23, preferentially expressed in the ventrolateral thalamic nucleus of the brain
72. The autosomal dominant hypophosphatemic rickets (ADHR) gene is a secreted polypeptide overexpressed by tumors that cause phosphate wasting
73. Hereditary hypophosphatemic rickets with hypercalciuria
74. Hypercalciuric hypophosphatemic rickets, mineral balance, bone histomorphometry, and therapeutic implications of hypercalciuria
75. NPT2 is not the gene responsible for hereditary hypophosphatemic rickets with hypercalciuria (HHRH) in a Bedouin kindred
76. Autosomal recessive hypophosphataemic rickets with hypercalciuria is not caused by mutations in the type II renal sodium/phosphate cotransporter gene