Molecular mechanisms of mutations in factor XIII A-subunit deficiency: In vitro expression in COS-cells demonstrates intracellular degradation of the mutant proteins

Thrombosis and Haemostasis

Volumn 77, Issue 6, 1997, Pages 1068-1072

  Mikkola, Hanna ^a,b   Muszbek, Laszlo ^c   Haramura, Gizela ^c   Hämäläinen, Eija ^a,b   Jalanko, Anu ^d   Palotie, Aarno ^a,b  

^a UNIVERSITY OF HELSINKI   (Finland)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^c UNIVERSITY OF DEBRECEN   (Hungary)

^d NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 13; CELL PROTEIN; COMPLEMENTARY DNA; MESSENGER RNA; MUTANT PROTEIN; PROTEIN SUBUNIT;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; AUTOSOMAL RECESSIVE DISORDER; BLEEDING DISORDER; BLOOD CLOTTING FACTOR 13 DEFICIENCY; CONTROLLED STUDY; DNA TRANSFECTION; ENZYME ACTIVITY; GENE MUTATION; GENETIC TRANSFECTION; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MISSENSE MUTATION; MOLECULAR GENETICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN TERTIARY STRUCTURE; STEREOCHEMISTRY;

EID: 0030845153     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0038-1656113     Document Type: Article

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