Activation of the human transglutaminase 1 promoter in transgenic mice: Terminal differentiation-specific expression of the TGM1-lacZ transgene in keratinized stratified squamous epithelia

Human Molecular Genetics

Volumn 6, Issue 13, 1997, Pages 2223-2231

  Yamada, Keiko ^a   Matsuki, Masato ^a   Morishima, Yohichi ^a   Ueda, Eiichiro ^a   Tabata, Kohich ^a   Yasuno, Hirokazu ^a   Suzuki, Misao ^b   Yamanishi, Kiyofumi ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b KUMAMOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; MESSENGER RNA; PHORBOL ESTER; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME HISTOCHEMISTRY; EPIDERMIS; EPITHELIUM; ESCHERICHIA COLI; FEMALE; GENE ACTIVATION; IN SITU HYBRIDIZATION; KERATINOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; SKIN; TISSUE SPECIFICITY; TRANSCRIPTION REGULATION; TRANSGENE; TRANSGENIC MOUSE;

EID: 0030830588     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/6.13.2223     Document Type: Article

References (66)

1. Folk, J. E. (1980) Transglutaminases. Annu. Rev. Biochem., 49, 517-531.
2. Greenberg, C. S., Birckbichler, P. J., and Rice, R. H. (1991) Transglutaminases: multifunctional cross-linking enzymes that stabilize tissues. FASEB J., 5, 3071-3077.
3. Thacher, S. M. and Rice, R. H. (1985) Keratinocyte-specific transglutaminase of cultured human epidermal cells: Relation to cross-linked envelope formation and terminal differentiation. Cell, 40, 685-695.
4. Ta, B. M., Gallagher, G. T., Chakravarty, R. and Rice, R. H. (1990) Keratinocyte transglutaminase in human skin and oral mucosa:cytoplasmic localization and uncoupling of differentiation markers. J Cell Sci., 95, 631-638.
5. Roop, D. R. (1995) Defects in the barrier. Science, 267, 474-475.
6. Parenteau, N. L., Pilato, A. and Rice, R. H. (1986) Induction of keratinocyte type-I transglutaminase in epithelial cells of the rat. Differentiation, 33, 130-141.
7. Schroeder, W. T., Thacher, S. M., Stewart-Galetka, S., Annarella, M., Chema, D., Siciliano, M. J., Davies, P. J. A.,Tang, H. -Y., Sowa, B. A. and Duvic, M. (1992) Type I keratinocyte transglutaminase: expression in human skin and psoriasis. J. Invest. Dermatol, 99, 27-34.
8. Kim, S.-Y, Chung, S.-I., Yoneda, K. and Steinert, P. M. (1995) Expression of transglutaminase I in human epidermis. J. Invest. Dermatol., 104, 211-217.
9. Rice, R. H. and Green, H. (1979) Presence in human epidermal cells of a soluble protein precursor of the cross-linked envelope: Activation of the cross-linking by calcium ions. Cell, 18, 681-694.
10. Zettergren, J. G., Peterson, L. L. and Wuepper, K. D. (1984) Keratolinin: the soluble substrate of epidermal transglutaminase from human and bovine tissue. Proc. Natl. Acad. Sci. USA, 81, 238-242.
11. Takahashi, M., Tezuka, T. and Katunuma, N. (1992) Phosphorylated cystatin a is a natural substrate of epidermal transglutaminase for formation of skin comified envelope. FEBS Lett., 308, 79-82.
12. Mehrel, T., Hohl, D., Rothnagel, J. A., Longley, M. A., Bundman, D., Cheng, C., Lichti, U., Bisher, M. E., Steven, A. C., Steinert, P. M., Yuspa, S. H. and Roop, D. R. (1990) Identification of a major keratinocyte cell envelope protein, loricrin. Cell, 61, 1103-1112.
13. Hohl, D., Mehrel, T., Lichti, U., Turner, M. L., Roop, D. R. and Steinert, P. M. (1991) Characterization of human loricrin: structure and function of a new class of epidermal cell envelope proteins, J. Biol. Chem., 266, 6626-6636.
14. Molhuizen, H. O. F., Alkemade, H. A. C., Zeeuwen, P. L. J. M., De Jongh, G. J., Wieringa, B. and Schalkwijk, J. (1993) SKALP/Elafin: an elastase inhibitor from cultured human keratinocytes. Purification, cDNA sequence, and evidence for transglutaminase cross-linking. J. Biol. Chem., 268, 12028-12032.
15. Steinert, P. M. and Marekov, L. N. (1995) The proteins elafin, filaggrin, keratin intermediate filaments, loricrin, and small proline-rich proteins 1 and 2 are isodipeptide cross-linked components of the human epidermal cornified cell envelope. J. Biol. Chem., 270, 17702-17711.
16. Pfundt, R., Van Ruissen, F., Van Vlijmen-Willems, I. M. J. J., Alkemade, H. A. C.,Zeeuwen, P. L. J. M., Jap, P. H., Dijkman, H., Fransen, J., Croes, H., Van Erp, P. E. J. and Schalkwijk, J. (1996) Constitutive and inducible expression of SKALP/elafin provides anti-elastase defense in human epithelia. J. Clin. Invest., 98, 1389-1399.
17. Marvin, K. W., George, M. D., Fujimoto, W., Saunders, N. A., Bernacki, S. H., and Jetten, A. M. (1992) Cornifin, a cross-linked envelope precursor in keratinocytes that is down-regulated by retinoids. Proc. Natl. Acad. Sci. USA, 89, 11026-11030.
18. Gibbs, S., Fijneman, R., Wiegant, J., Geurts van Kessel, A., van de Putte, P. and Backendorf, C. (1993) Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline-rich proteins. Genomics, 16, 630-637.
19. Ming, M. E., Daryanani, H. A., Roberts, L. P., Baden, H. P. and Kvedar, J. C. (1994) Binding of keratin intermediate filaments (K10) to the cornified envelope in mouse epidermis: implications for barrier function. J. Invest. Dermatol., 103, 780-784.
20. Ruhrberg, C., Hajibagheri, M. A. N., Simon, M., Dooley, T. P. and Watt, F. M. (1996) Envoplakin, a novel precursor of the cornified envelope that has homology to desmoplakin. J. Cell Biol., 134, 715-729.
21. Robinson, N. A., Lapic, S., Welter, J. F., and Eckert, R. L. (1997) S100A11, S100A10, annexin I, desmosomal proteins, small proline-rich proteins, plasminogen activator inhibitor-2, and involucrin are components of the cornified envelope of cultured human epidermal keratinocytes. J. Biol. Chem., 272, 12035-12046.
22. Kim, I.-G., McBride, O. W., Wang, M., Kim, S. -Y, Idler, W. W. and Steinert, P. M. (1992) Structure and organization of the human transglutaminase 1 gene. J. Biol. Chem., 267, 7710-7717.
23. Yamanishi, K., Inazawa, J., Liew, F.-M., Nonomura, K., Ariyama, T., Yasuno, H., Abe, T., Doi, H., Hirano, J. and Fukushima, S. (1992) Structure of the gene for human transglutaminase 1. J. Biol. Chem., 267, 17858-17863.
24. Russell, L. J., DiGiovanna, J. J., Hashem, N., Compton, J. G. and Bale, S. J. (1994) Linkage of autosomal recessive lamellar ichthyosis to chromosome 14q. Am. J. Hum. Genet., 55, 1146-1152.
25. Lentz, C. L. and Altman, J. (1968) Lamellar ichthyosis: the natural clinical course of collodion baby. Arch. Dermatol., 97, 3-13.
26. Williams, M. L. and Elias, P. M. (1985) Heterogeneity in autosomal recessive ichthyosis: Clinical and biochemical differentiation of lamellar ichthyosis and nonbullous congenital ichthyosiform erythroderma. Arch. Dermatol., 121, 477-488.
27. Huber, M., Rettler, I., Bernasconi, K., Frenk, E., Lavrijsen, S. P. M., Ponec, M., Bon, A., Lautenschlager, S., Schorderet, D. F. and Hohl, D. (1995) Mutations of keratinocyte transglutaminase in lamellar ichthyosis. Science, 267, 525-528.
28. Russell, L. J., DiGiovanna, J. J., Rogers, G. R., Steinert, P. M., Hashem, N., Compton, J. G. and Bale, S. J. (1995) Mutations in the gene for transglutaminase 1 in autosomal recessive lamellar ichthyosis. Nature Genet., 9, 279-283.
29. Parmentier, L., Blanchet-Bardon, C., Nguyen, S., Prud'homme, J. -F., Dubertret, L. and Weissenbach, J. (1995) Autosomal recessive lamellar ichthyosis: identification of a new mutation in transglutaminase 1 and evidence for genetic heterogeneity. Hum. Mol. Genet., 4, 1391-1395.
30. Parmentier, L., Lakhdar, H., Blanchet-Bardon, C., Marchand, S., Dubertret, L. and Weissenbach, J. (1996) Mapping of a second locus for Lamellar ichthyosis to chromosome 2q33-35. Hum. Mol. Genet., 5, 555-559.
31. Huber, M., Rettler, I., Bernasconi, K., Wyss, M. and Hohl, D. (1995) Lamellar ichthyosis is genetically heterogeneous - cases with normal keratinocyte transglutaminase. J. Invest. Dermatol., 105, 653-654.
32. Floyd, E. E. and Jetten, A. M. (1989) Regulation of type I (Epidermal) transglutaminase mRNA levels during squamous differentiation: down regulation by retinoid. Mol. Cell. Biol., 9, 4846-4851.
33. Polakowska, R. R., Herting, E. and Goldsmith, L. A. (1991) Isolation of cDNA for human epidermal type I transglutaminase. J. Invest. Dermatol., 96, 285-288.
34. 1b,- and calcium-stimulated human keratinocytes. Biochem. Biophys. Res. Commun., 190, 688-694.
35. Liew, F.-M. and Yamanishi, K. (1992) Regulation of transglutaminase 1 gene expression by 12-0-tetradecanoylphorbol-13-acetate, dexamethasone, and retinoic acid in cultured human keratinocytes, Exp. Cell Res., 202, 310-315.
36. K) gene expression in cultured primary mouse epidermal keratinocytes induced to terminally differentiate by calcium. J. Invest. Dermatol., 102, 409-414.
37. Saunders, N. A. and Jetten, A. M. (1994) Control of growth regulatory and differentiation-specific genes in human epidermal keratinocytes by interferon γ. J. Biol. Chem., 269, 2016-2022.
38. Yamada, K., Yamanishi, K., Kakizuka, A., Kibe, Y., Doi, H. and Yasuno, H. (1994) Transcriptional regulation of human transglutaminase 1 gene by signaling systems of protein kinase C, RAR/RXR and Jun/Fos in keratinocytes. Biochem. Mol. Biol. Int., 34, 827-836.
39. Saunders, N. A., Bernacki, S. H., Vollberg, T. M. and Jetten, A. M. (1993) Regulation of transglutaminase type 1 expression in squamous differentiating rabbit tracheal epithelial cells and human epidermal keratinocytes: effects of retinoic acid and phorbol esters. Mol. Endocrinol., 7, 387-398.
40. Van Bokhoven, H., Rawson, R. B., Merkx, G. F. M., Cremers, F. P. M. and Seabra, M. C. (1996) cDNA cloning and chromosomal localization of the genes encoding the α- and β-subunits of human Rab geranylgeranyl transferase: 3′ end of the α-subunit gene overlaps with the transglutaminase 1 gene promoter. Genomics, 38, 133-140.
41. Mariniello, L., Qin, Q., Jessen, B. A. and Rice, R. H. (1995) Keratinocyte transglutaminase promoter analysis - identification of a functional response element. J. Biol. Chem., 270, 31358-31363.
42. Byrne, C., Tainsky, M. and Fuchs, E. (1994) Programming gene expression in developing epidermis. Development, 120, 2369-2383.
43. DuBrul, E. F. (1972) Fine structure of epidermal differentiation in the mouse. J. Ex. Zool., 181, 145-158.
44. Schweizer, J. and Winter, H. (1982) Keratin polypeptide analysis in fetal and in terminally differentiating newborn mouse epidermis. Differentiation, 22, 19-24.
45. Bickenbach, J. R., Greer, J. M., Bundman, D. S., Rothnagel, J. A. and Roop, D. R. (1995) Loricrin expression is coordinated with other epidermal proteins and the appearance of lipid lamellar granules in development. J. Invest. Dermatol., 104, 405-410.
46. Lazarus, G. S., Hatcher, V. B. and Levine, N. (1975) Lysosomes and the skin. J. Invest. Dermatol., 65, 259-271.
47. Ueda, E., Ohno, S., Kuroki, T., Livneh, E., Yamada, K., Yamanishi, K. and Yasuno, H. (1996) The η isoform of protein kinase C mediates transcriptional activation of the human transglutaminase 1 gene. J. Biol. Chem., 271, 9790-9794.
48. 2+-independent isoform of protein kinase C in epithelial tissues, in association with epithelial differentiation. Cell Growth Differ., 4, 167-175.
49. 2+independent protein kinase C, in normal human skin and skin diseases. J. Invest. Dermatol., 101, 858-863.
50. Michel, S., Bernerd, F., Jetten, A. M., Floyd, E. E., Shroot, B. and Reichert, U. (1992) Expression of keratinocyte transglutaminase mRNA revealed by in situ hybridization. J. Invest. Dermatol., 98, 364-368.
51. Nonomura, K., Yamanishi, K., Hosokawa, Y., Doi, H., Hirano, J., Fukushima, S. and Yasuno, H. (1993) Localization of transglutaminase 1 mRNA in normal and psoriatic epidermis by non-radioactive in situ hybridization. Br. J. Dermatol., 128, 23-28.
52. Doi, H., Ueda, E., Yamanishi, K., Fujii, Y. Kamoda, H. and Yasuno, H. (1996) Transcriptional regulation of human transglutaminase 1 gene by Sp1. J. Clin. Exp. Med., 177, 281-282.
53. Lee, J.-H., Jang, S. I., Yang, J. M., Markova, N. G. and Steinert, P. M. (1996) The proximal promoter of the human transglutaminase 3 gene - Stratified squamous epithelial-specific expression in cultured cells is mediated by binding of Sp1 and ets transcription factors to a proximal promoter element. J. Biol. Chem., 271, 4561-4568.
54. Takahashi, H. and Iizuka, H. (1993) Analysis of the 5′-upstream promoter region of human involucrin gene: activation by 12-0-tetradecanoylphorbo-1-13-acetate. J. Invest. Dermatol., 100, 10-15.
55. Lohman, F. P., Gibbs, S., Fischer, D. F., Borgstein, A. M. B., van de Putte, P. and Backendorf, C. (1997) Involvement of c-JUN in the regulation of terminal differentiation genes in normal and malignant keratinocytes. Oncogene, 14, 1623-1627.
56. Wang, X. M., Zinkel, S., Polonsky, K., and Fuchs, E. (1997) Transgenic studies with a keratin promoter-driven growth hormone transgene: Prospects for gene therapy. Proc. Natl. Acad. Sci. USA, 94, 219-226.
57. Ha to the epidermis of transgenic mice induces hyperplasia, hyperkeratosis and papillomas. Mol. Carcinogen., 7, 99-110.
58. Greenhalgh, D. A., Rothnagel, J. A., Wang, X.-J., Quintanilla, I. M., Orengo, C. C., Gagne, T. A., Bundman, D. S., Longley, M. A., Fisher, C. and Roop, D. R. (1993) Hyperplasia, hyperkeratosis and benign tumor production in transgenic mice by a targeted v-fos oncogene suggest a role fos in epidermal differentiation and neoplasia. Oncogene, 8, 2145-2157.
59. Carroll, J. M., Albers, K. M., Garlick, J. A., Harrington, R. and Taichman, L. B. (1993) Tissue- and stratum-specific expression of the human involucrin promoter in transgenic mice. Proc. Natl. Acad. Sci. USA, 90, 10270-10274.
60. Crish, J. F., Howard, J. M., Zaim, T. M., Murthy, S. and Eckert, R. L. (1993) Tissue-specific and differentiation-appropriate expression of the human involucrin gene in transgenic mice: An abnormal epidermal phenotype. Differentiation, 53, 191-200.
61. Hengge, U. R., Chan, E. F., Foster, R. A., Walker, P. S. and Vogel, J. C. (1995) Cytokine gene expression in epidermis with biological effects following injection of naked DNA. Nature Genet., 10, 161-166.
62. Takahashi, K. and Coulombe, P. A. (1997) Defining a region of the human keratin 6a gene that confers inducible expression in stratified epithelia of transgenic mice. J. Biol. Chem., 272, 11979-11985.
63. Rasheed, S., Nelson-Rees, W. A., Toth, E. M., Arnstein, P. and Gardner, B. (1974) Characterization of a newly derived human sarcoma cell line (HT-1080). Cancer, 33, 1027-1033..
64. Toyonaga, T., Hino, O., Sugai, S., Wakasugi, S., Abe, K., Shichiri, M. and Yamamura, K. (1994) Chronic active hepatitis in transgenic mice expressing interferon-γ in the liver. Proc. Natl Acad. Sci. USA, 91, 614-618.
65. Kaufman, M. H. (1995) In Kaufman, M. H. (ed.) The atlas of mouse development. Academic Press Ltd, London, UK. pp.5-8.
66. Nonomura, K., Yamanishi, K., Yasuno, H., Nara, K. and Hirose, S. (1994) Up-regulation of elafin/SKALP gene expression in psoriatic epidermis. J. Invest. Dermatol., 103, 88-91.