The effect of enalapril and verapamil on the left ventricular hypertrophy and the left ventricular cardiomyocyte numerical density in rats submitted to nitric oxide inhibition

International Journal of Experimental Pathology

Volumn 82, Issue 2, 2001, Pages 115-122

  Pereira, Leila Maria Meirelles ^a   Mandarim de Lacerda, Carlos Alberto ^a  

^a STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Antihypertensive drugs; Hypertension; Hypertrophy; Myocardium; Nitric oxide; Stereology

Indexed keywords

ENALAPRIL; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; VERAPAMIL;

ANALYTIC METHOD; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD PRESSURE REGULATION; CELL DENSITY; CONTROLLED STUDY; DRUG EFFECT; HEART LEFT VENTRICLE HYPERTROPHY; HEART MUSCLE CELL; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STEREOLOGY;

ANALYSIS OF VARIANCE; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; CALCIUM CHANNEL BLOCKERS; CELL COUNT; ENALAPRIL; ENZYME INHIBITORS; HYPERTROPHY, LEFT VENTRICULAR; MALE; MYOCARDIUM; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; PLETHYSMOGRAPHY; RATS; RATS, WISTAR; STATISTICS, NONPARAMETRIC; VERAPAMIL;

EID: 0034921042     PISSN: 09599673     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2613.2001.00172.x     Document Type: Article

References (58)

1. Ischemic myocardial injury and ventricular remodelling
2. Cardiomyocyte cell death in the diseased heart
3. Ca2 channel blockers verapamil and nifedipine inhibit apoptosis induced by 25-hydroxycholesterol in human aortic smooth muscle cells
4. Cardiac weight in hypertension induced by nitric oxide synthase blockade
5. Is apoptosis an important pathogenic factor in cardiovascular disease?
6. Lipid abnormalities in myocardial cell injury
7. Modulation of the myocardium response to ischemia
8. Recent stereological methods for cell biology: A brief survey
9. Long-term nitric oxide synthase inhibition and distensibility of carotid artery in infant rats
10. Apoptosis in hypertensive heart disease
11. Smooth muscle apoptosis during vascular regression in spontaneously hypertensive rats
12. Reversibility of left ventricular hypertrophy by antihypertensive drugs
13. Echocardiography and Doppler-echocardiography in hypertension
14. Reversal of left ventricular hypertrophy in hypertensive patients treated with methyldopa
15. Influence of left ventricular mass regression on cardiac function in hypertensive elderly individuals
16. Comparison of bisoprolol and verapamil in hypertension: Influence on left ventricular mass and function - A pilot study
17. Effects of ACE inhibition on cardiomyocyte apoptosis in dogs with heart failure
18. Myocyte death in the failure human heart is gender dependent
19. Notes on the estimation of the numerical density of arbitrary profiles: The edge effect
20. Some new, simple and efficient stereological methods and their use in pathological research and diagnosis
21. Reversal of cardiac and vascular hypertrophy by antihypertensive therapy
22. Effects of captopril and minoxidil on left ventricular hypertrophy in resistant hypertensive patients: A 6 months double-bind comparison
23. Myocyte cellular hyperplasia and myocyte cellular hypertrophy contribute to chronic ventricular remodeling in coronary artery narrowing-induced cardioyopathy in rats
24. Signals for cardiac muscle hypertrophy in hypertension
25. Stereology in the normal and pathological morphologic research
26. What is the interest of normal and pathological morphological research to be quantitative? The example of the stereology
27. Numerical density of cardiomyocytes in chronic nitric oxide synthesis inhibition
28. Effects of calcium channel blockers on cellular apoptosis
29. Left ventricular adaptation to chronic pressure overload induced by inhibition of nitric oxide synthase in rats
30. Orthogonal triplet probes: An efficient method for unbiased estimation of length and surface of objects with unknown orientation in space
31. Chronic inhibition of nitric oxide synthesis causes coronary microvascular remodelling in rats
32. Apoptosis in the failing human heart
33. Apoptosis in the failure human heart
34. Gender differences and aging: Effects on the human heart
35. Cardiomyocyte nuclear and possible cellular hyperplasia contribute to ventricular remodelling in the hypertrophic senescent heart in humans
36. Quantitative examination of the cardiac cardiomyocytes in hypertensive rats under chronic inhibition of nitric oxide synthesis
37. Myocardial microcirculation stereological changes in rats subject to nitric oxide synthesis inhibition
38. Effect of antihypertensive drugs on the myocardial microvessels in rats with nitric oxide blockade
39. Stereology of the myocardium in hypertensive rats. Differences in relation to the time of inhibition of nitric oxide synthesis
40. Stereology and immunohistochemistry of the myocardium in experimental hypertension: Long-term and low-dosage administration of inhibitor of the nitric oxide synthesis
41. Myofibroblast accumulation in healing rat myocardium due to long-term low-dosage nitric oxide synthesis inhibition
42. End-stage cardiac failure in humans is coupled with the induction of proliferating cell nuclear antigen and nuclear mitotic division in ventricular myocytes
43. Regression of left ventricular hypertrophy in hypertension
44. Renin-angiotensin-aldosterone system and hypertensive cardiac hypertrophy
45. Impairment of myocyte contractility following coronary artery narrowing is associated with activation of the myocyte IGF-1 autocrine system, enhanced expression of late growth related genes, DNA-synthesis and myocyte nuclear mitotic division in rats
46. Pathologic fibrosis and connective tissues matrix in left ventricular hypertrophy due to chronic arterial hypertension in humans
47. Apoptosis in heart failure
48. Progression of heart failure: A role for interstitial fibrosis
49. Simple method for volumetry of organs in quantitative stereology
50. The effects of antihypertensive therapy on left mass in elderly patients
51. Lisinopril reverses left ventricular hypertrophy through improved aortic compliance
52. Pathophysiological principles of the relation between myocardial hypertrophy of the left ventricle and its regression
53. Left ventricular hypertrophy regression as a process with variable biological implications
54. Progression und regression der herzhypertrophie beim arteriellen bluthochdruck: Pathophysiologie und klinik
55. The origins of cardiac hypertrophy
56. A Important role of tissue angiotensin-converting enzyme activity in the pathogenesis of coronary vascular and myocardial structural changes induced by long-term blockade of nitric oxide synthesis in rat
57. Prevention of apoptosis reperfusion renal injury by calcium channel blockers