Prevention of apoptosis reperfusion renal injury by calcium channel blockers

Experimental and Toxicologic Pathology

Volumn 51, Issue 3, 1999, Pages 209-212

  Toronyi, Éva ^a   Hamar, János ^a   Ferner, Ferenc ^b   Szende, Béla ^a  

^a SEMMELWEIS UNIVERSITY OF MEDICINE   (Hungary)

^b Experimental Department   (Hungary)

Author keywords

Apoptosis; Calcium channel blockers; Kidney, ischemia; Renal injury; Reperfusion, kidney

Indexed keywords

BEPRIDIL; CALCIUM CHANNEL BLOCKING AGENT; FENDILINE; NIFEDIPINE; VERAPAMIL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; INTRAARTERIAL DRUG ADMINISTRATION; KIDNEY INJURY; KIDNEY ISCHEMIA; KIDNEY TUBULE EPITHELIUM; MALE; NONHUMAN; RAT; REPERFUSION INJURY;

ANIMALIA;

EID: 0032934001     PISSN: 09402993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0940-2993(99)80098-0     Document Type: Article

References (9)

1. BUTTKE Th, SANDSTROM P: Oxidative stress as a mediator of apoptosis. Immunology Today 1994; 15: 495-496
2. EPSTEIN M: Calcium antagonists and renal protection. Arch Intern Med 1992; 152: 1573-1584
3. KEDAR I, COHEN J, JACOB ET, RAVID M: Alleviation of experimental ischaemic acute renal failure by dimethyl sulfoxide. Nephron 1981; 29: 55-58
4. KERR JFR, WHYLLIE AH, CURRIE AR: Apoptosis: a basic biological phenomenon with wideranging implications in tissue kinetics. Br J Cancer 1972; 26: 239-257
5. PALLER MS: The cell biology of reperfusion injury in the kidney. Journal of Investigative Medicine 1994; 42: 632-639
6. PALLER MS, GREENE EL: Role of calcium in reperfusion injury of the kidney. Ann NY Acad Sei 1994; 723: 59-70
7. SCHUMER M, COLOMBEL MC, SAWCZUK IS, et al.: Morphologic, biochemical and molecular evidence of apoptosis during the reperfusion phase after brief periods of renal ischaemia. American Journal of Pathology 1992; 140: 831-838
8. SCHWERTSCHLAG U, SCHRIER RW, WILSON P: Beneficial effects of calcium channel blockers and calmodulin binding drugs on in vitro renal cell anoxia. Journal of Pharmacology and Experimental Therapeutics 1986; 238: 119-124
9. TAKENAKA M, TATSUKAWA Y, DOHI K, et al.: Protectiv effects of Alfa-tocoferol and coenzyme Q10 on warm ischemic damage of the rat kidney. Transplantation 1981; 32: 137-141