A sex-related difference in the hypertrophic versus hyperplastic response of vascular smooth muscle cells to repeated passaging in culture

Histology and Histopathology

Volumn 16, Issue 3, 2001, Pages 675-684

  Bacakova L ^a   Pellicciari, C ^a   Bottone, M G ^a   Lisa V ^a   Mares V ^a  

^a INSTITUTE OF PHYSIOLOGY   (Czech Republic)

Author keywords

Alpha actin; Alpha v integrins; Cell proliferation; Flow cytometry; Gender differences; Polyploidization; Rat aortic smooth muscle cells; Vinculin

Indexed keywords

ALPHA ACTIN; BROXURIDINE; CELL PROTEIN; DNA; INTEGRIN; TRYPSIN; VINCULIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ADHESION; CELL DENSITY; CELL PROLIFERATION; CELL VOLUME; CHROMOSOME NUMBER; CYTOSKELETON; DNA SYNTHESIS; DONOR; DYSPLASIA; FEMALE; FLOW CYTOMETRY; GENDER; GROWTH STIMULATION; HISTOGRAM; HYPERPLASIA; MALE; MOLECULE; MUSCLE FIBER CULTURE; MUSCLE HYPERTROPHY; NONHUMAN; PLOIDY; POLYPLOIDY; POPULATION DENSITY; PROTEIN CONTENT; PROTEIN EXPRESSION; RAT; SEX DIFFERENTIATION; SMOOTH MUSCLE FIBER; THORACIC AORTA; VASCULAR DISEASE; VASCULAR SMOOTH MUSCLE;

ACTINS; ANIMALS; ANTIGENS, CD; CELL ADHESION; CELL DIVISION; CELL SIZE; CELLS, CULTURED; CYTOSKELETAL PROTEINS; DNA; FEMALE; HYPERPLASIA; HYPERTROPHY; INTEGRIN ALPHAV; MALE; MEMBRANE PROTEINS; MUSCLE PROTEINS; MUSCLE, SMOOTH, VASCULAR; PLOIDIES; RATS; SEX CHARACTERISTICS; VINCULIN;

ANIMALIA;

EID: 0034915208     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. Transforming growth factor-beta 1 and the development of vascular hypertrophy in hypertension
2. Estrogen inhibits cuff-induced intimal thickening of rat femoral artery: Effects on migration and proliferation of vascular smooth muscle cells
3. Gender differences in growth of vascular smooth muscle cells isolated from hypertensive and normotensive rats
4. Sex-related differences in the migration and proliferation of rat aortic smooth muscle cells in short and long term culture
5. Sex-determined differences in growth and morphology of vascular smooth muscle cells in cultures from newborn rat
6. Gender-related differences in adhesion, growth and differentiation of vascular smooth muscle cells are enhanced in serum-deprived cultures
7. Polyploid nuclei in human artery wall smooth muscle cells
8. Isolation of two morphologically distinct cell lines from rat arterial smooth muscle expressing high tumorigenic potentials
9. Cell polyploidy: Its relation to tissue growth and function
10. Vascular smooth muscle cell hypertrophy during maturation in rat thoracic aorta. Volumetric and morphometric studies
11. Smooth muscle cell hypertrophy and hyperplasia in the thoracic aorta of spontaneously hypertensive rats
12. Alterations in beta-adrenoceptors and polyploidy in cultured aortic smooth muscle cells from different age groups of spontaneously hypertensive rats and Wistar-Kyoto rats
13. Examination of a spontaneously transformed aortic smooth muscle cell line. I. Morphological examinations
14. Vascular smooth muscle polyploidy in genetic hypertension: The role of angiotensin II
15. Vascular smooth muscle cell polyploidy and cardiomyocyte hypertrophy due to chronic NOS inhibition in vivo
16. Vitronectin expression and interaction with receptors in smooth muscle cells from human atheromatous plaque
17. 17 beta-estradiol and smooth muscle cell proliferation in aortic cells of male and female rats
18. Suppression of vinculin expression by antisense transfection confers changes in cell morphology, motility, and anchorage-dependent growth of 3T3 cells
19. Gender-related differences in vascular smooth muscle cell proliferation: Implications for prevention of atherosclerosis
20. Accelerated aging of dermal fibroblast-like cells from the senescence-accelerated mouse (SAM): Acceleration of changes in DNA ploidy associated with in vitro cellular aging
21. Integrins, cytoskeletal and extracellular matrix proteins in developing smooth muscle cells of human aorta
22. Isolation and culture of a tetraploid subpopulation of smooth muscle cells from the normal rat aorta
23. Aging of chick embryo fibroblasts
24. Proliferation of human aortic vascular smooth muscle cells in culture is modulated by active TGF beta
25. Incidence of multinucleated and polyploid aortic smooth muscle cells cultured from different age groups of spontaneously hypertensive rats
26. Ploidy in mesenteric vessels of aged spontaneously hypertensive and Wistar-Kyoto rats
27. The influence of angiotensin II on sex-dependent proliferation of aortic VSMC isolated from SHR
28. Protein measurement with the folin phenol reagent
29. Donor-age-related changes in the morphology, growth potential, and collagen biosynthesis in rat fibroblast subpopulations in vitro
30. Differential response in cell proliferation to beta estradiol in coronary arterial vascular smooth muscle cells obtained from mature female versus male animals
31. Control of hypertrophic versus hyperplastic growth of vascular smooth muscle cells
32. Transforming growth factor beta induced growth inhibition and cellular hypertrophy in cultured vascular smooth muscle cells
33. Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness
34. Spontaneous apoptosis of thymocytes is uncoupled with progression through the cell cycle
35. Cytoskeletal changes induced by excess extracellular matrix impair endothelial cell replication
36. Growth kinetics as a function of ploidy in diploid, tetraploid, and octaploid smooth muscle cells derived from the normal rat aorta
37. Vessel wall growth control
38. Replication of smooth muscle cells in vascular disease
39. Mitogenic effect of angiotensin II on rat carotid arteries and type II or III mesenteric microvessels but not type I mesenteric microvessels is mediated by endogenous basic fibroblast growth factor
40. Differences in proliferation of primary cultures of vascular smooth muscle cells taken from male and female rats
41. Biological significance of liver cell polyploidy: An hypothesis
42. Estradiol effect on rate of proliferation of rat carotid segments: Effect of gender and tamoxifen
43. Cellular mechanisms of diabetic vascular hypertrophy
44. The synergistic activity of alphavbeta3 integrin and PDGF receptor increases cell migration
45. Catecholamine-induced polyploidization in vascular smooth muscle cells