SCOPUS 정보 검색 플랫폼

Volumn 15, Issue 7, 2001, Pages 1081-1088

The association of the TEL-AML1 chromosomal translocation with the accumulation of methotrexate polyglutamates in lymphoblasts and with ploidy in childhood B-progenitor cell acute lymphoblastic leukemia: A Pediatric Oncology Group study

(11) Whitehead, V M a,b Payment, C a Cooley, L c Lauer, S J d Mahoney, D H c Shuster, J J e Vuchich, M J a Bernstein, M L f Look, A T g Pullen, D h Camitta, B i

a RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE (Canada)

b MCGILL UNIVERSITY (Canada)

c BAYLOR COLLEGE OF MEDICINE (United States)

d EMORY UNIVERSITY SCHOOL OF MEDICINE (United States)

e University of Florida ^* (United States)

f UNIVERSITY OF MONTREAL (Canada)

g DANA FARBER CANCER INSTITUTE (United States)

h UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE (United States)

i CHILDREN S HOSPITAL OF WISCONSIN (United States)

Author keywords

Hyperdiploid; Lymphoblast; Methotrexate; Polyglutamates; TEL AML1; Translocation

Indexed keywords

METHOTREXATE POLYGLUTAMATE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; B CELL LEUKEMIA; CELL LEVEL; CHILDHOOD LEUKEMIA; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; DIPLOIDY; FEMALE; GENETIC TRANSCRIPTION; HUMAN; LYMPHOBLAST; MAJOR CLINICAL STUDY; MALE; PRE B LYMPHOCYTE; PRESCHOOL CHILD; PRIORITY JOURNAL; TREATMENT PLANNING;

EID: 0034906512 PISSN: 08876924 EISSN: None Source Type: Journal
DOI: 10.1038/sj.leu.2402165 Document Type: Article

Times cited : (21)

References (46)

1
- 0029140694
- Childhood leukemias
- (1995) New Engl J Med , vol.332 , pp. 1618-1630
- Pui, C.-H.¹

2
- 0031459131
- Childhood acute lymphoblastic leukemia
- (1997) Oncologist , vol.2 , pp. 374-380
- Rubnitz, J.E.¹ Pui, C.H.²

3
- 0025091057
- Philadelphia chromosome positive childhood acute lymphoblastic leukemia: Clinical and cytogenetic characteristics and treatment outcome. A Pediatric Oncology Group study
- (1990) Blood , vol.76 , pp. 489-494
- Crist, W.¹ Carroll, A.² Shuster, J.³ Jackson, J.⁴ Head, D.⁵ Borowitz, M.⁶ Behm, F.⁷ Link, M.⁸ Steuber, P.⁹ Ragab, A.¹⁰ Hirt, A.¹¹ Brock, B.¹² Land, V.¹³ Pullen, J.¹⁴

4
- 0034611661
- Outcome of treatment in children with Philadelphia chromosome-positive acute lymphoblastic leukemia
- (2000) N Engl J Med , vol.342 , pp. 998-1006
- Arico, M.¹ Valsecchi, M.G.² Camitta, B.³ Schrappe, M.⁴ Chessells, J.⁵ Baruchel, A.⁶ Gaynon, P.⁷ Silverman, L.⁸ Janka-Schaub, G.⁹ Kamps, W.¹⁰ Pui, C.H.¹¹ Masera, G.¹²

5
- 0021969545
- Prognostic importance of blast cell DNA content in childhood acute lymphoblastic leukemia
- (1985) Blood , vol.65 , pp. 1079-1086
- Look, A.T.¹ Roberson, P.K.² Williams, D.L.³ Rivera, G.⁴ Bowman, W.P.⁵ Pui, C.-H.⁶ Ochs, J.⁷ Abromowitch, M.⁸ Kalwinsky, D.⁹ Dahl, G.V.¹⁰ George, S.¹¹ Murphy, S.B.¹²

6
- 0026518781
- Ploidy of lymphoblasts is the strongest predictor of treatment outcome in B-progenitor cell acute lymphoblastic leukemia of childhood: A Pediatric Oncology Group study
- (1992) J Clin Oncol , vol.10 , pp. 606-613
- Trueworthy, R.¹ Shuster, J.² Look, T.³ Crist, W.⁴ Borowitz, M.⁵ Carroll, A.⁶ Frankel, L.⁷ Harris, M.⁸ Wagner, H.⁹ Haggard, M.¹⁰ Mosijczuk, A.¹¹ Pullen, J.¹² Steuber, P.¹³ Land, V.¹⁴

7
- 0026769756
- Trisomy of leukemic cell chromosomes 4 and 10 identifies children with B-progenitor cell acute lymphoblastic leukemia with a very low risk of treatment failure: A Pediatric Oncology Group study
- (1992) Blood , vol.79 , pp. 3316-3324
- Harris, M.B.¹ Shuster, J.J.² Carroll, A.³ Look, A.T.⁴ Borowitz, M.J.⁵ Crist, W.M.⁶ Nitschke, R.⁷ Pullen, J.⁸ Steuber, C.P.⁹ Land, V.J.¹⁰

8
- 0344333442
- Intermediate-dose intravenous methotrexate with intravenous mercaptopurine is superior to repetitive low-dose oral methotrexate with intravenous mercaptopurine for children with lower-risk B-lineage acute Pediatric Oncology Group phase III trial
- (1998) J Clin Oncol , vol.16 , pp. 246-254
- Mahoney D.H., Jr.¹ Shuster, J.² Nitschke, R.³ Lauer, S.J.⁴ Winick, N.⁵ Steuber, C.P.⁶ Camitta, B.⁷

9
- 0342445410
- Intensification with intermediate-dose intravenous methotrexate is effective therapy for children with lower-risk B-precursor acute lymphoblastic leukemia: A Pediatric Oncology Group study
- (2000) J Clin Oncol , vol.18 , pp. 1285-1294
- Mahoney D.H., Jr.¹ Shuster, J.J.² Nitschke, R.³ Lauer, S.⁴ Steuber, C.P.⁵ Camitta, B.⁶

10
- 0022446019
- Nonrandom involvement of the 12p12 breakpoint in chromosome abnormalities of childhood acute lymphoblastic leukemia
- (1986) Blood , vol.68 , pp. 69-75
- Raimondi, S.C.¹ Williams, D.L.² Callihan, T.³ Peiper, S.⁴ Rivera, G.K.⁵ Murphy, S.B.⁶

11
- 0028330771
- t(12;21): A new recurrent translocation in acute lymphoblastic leukemia
- (1994) Genes Chromos Cancer , vol.9 , pp. 186-191
- Romana, S.P.¹ Le Coniat, M.² Berger, R.³

12
- 0028890410
- Identification of cytogenetically undetected 12p13 translocations and associated deletions by fluorescence in situ hybridization
- (1995) Genes Chromos Cancer , vol.12 , pp. 66-69
- Kobayashi, H.¹ Rowley, J.D.²

13
- 0029056756
- Frequent loss of heterozygosity at the TEL gene locus in acute lymphoblastic leukemia of childhood
- (1995) Blood , vol.86 , pp. 38-44
- Stegmaier, K.¹ Pendse, S.² Barker, G.F.³ Bray-Ward, P.⁴ Ward, D.C.⁵ Montgomery, K.T.⁶ Krauter, K.S.⁷ Reynolds, C.⁸ Sklar, J.⁹ Donnelly, M.¹⁰ Bohlander, S.K.¹¹ Rowley, J.D.¹² Sallan, S.E.¹³ Gilliland, D.G.¹⁴ Golub, T.R.¹⁵

14
- 0028096970
- Fluorescence in situ hybridization mapping of translocations and deletions involving the short arm of human chromosome 12 in malignant hematologic diseases
- (1994) Blood , vol.84 , pp. 3473-3482
- Kobayashi, H.¹ Montgomery, K.T.² Bohlander, S.K.³ Adra, C.N.⁴ Lim, B.L.⁵ Kucherlapati, R.S.⁶ Donis-Keller, H.⁷ Holt, M.S.⁸ Le Beau, M.M.⁹ Rowley, J.D.¹⁰

15
- 0029004541
- Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia
- (1995) Proc Natl Acad Sci USA , vol.92 , pp. 4917-4921
- Golub, T.R.¹ Barker, G.F.² Bohlander, S.K.³ Hiebert, S.W.⁴ Ward, D.C.⁵ Bray-Ward, P.⁶ Morgan, E.⁷ Raimondi, S.C.⁸ Rowley, J.D.⁹ Gilliland, D.G.¹⁰

16
- 0029045087
- The t(12;21) of acute lymphoblastic leukemia results in a tel-AML1 gene fusion
- (1995) Blood , vol.85 , pp. 3662-3670
- Romana, S.P.¹ Mauchauffe, M.² Le Coniat, M.³ Chumakov, I.⁴ Le Paslier, D.⁵ Berger, R.⁶ Bernard, O.A.⁷

17
- 13344282725
- TEL/AML1 fusion resulting from a cryptic t(12;21) is the most common genetic lesion in pediatric ALL and defines a subgroup of patients with an excellent prognosis
- (1995) Leukemia , vol.9 , pp. 1985-1989
- Shurtleff, S.A.¹ Buijs, A.² Behm, F.G.³ Rubnitz, J.E.⁴ Raimondi, S.C.⁵ Hancock, M.L.⁶ Chan, G.C.-F.⁷ Pui, C.-H.⁸ Grosveld, G.⁹ Downing, J.R.¹⁰

18
- 0028805405
- High frequency of t(12;21) in childhood B-lineage acute lymphoblastic leukemia
- (1995) Blood , vol.86 , pp. 4263-4269
- Romana, S.P.¹ Poirel, H.² Leconiat, M.³ Flexor, M.-A.⁴ Mauchauffé, M.⁵ Jonveaux, P.⁶ Macintyre, E.A.⁷ Berger, R.⁸ Bernard, O.A.⁹

19
- 0031440492
- Incidence of TEL/AML11 fusion gene analyzed consecutively in children with acute lymphoblastic leukemia in relapse
- (1997) Blood , vol.90 , pp. 4933-4937
- Harbott, J.¹ Viehmann, S.² Borkhardt, A.³ Henze, G.⁴ Lampert, F.⁵

20
- 9244221153
- The 12;21 translocation involving TEL and deletion of the other TEL allele: Two frequently associated alterations found in childhood acute lymphoblastic leukemia
- (1996) Blood , vol.87 , pp. 2891-2899
- Raynaud, S.¹ Cavé, H.² Baens, M.³ Bastard, C.⁴ Cacheux, V.⁵ Grosgeorge, J.⁶ Guidal-Giroux, C.⁷ Guo, C.⁸ Vilmer, E.⁹ Marynen, P.¹⁰ Grandchamp, B.¹¹

21
- 0007055492
- TEL/AML-1 dimerizes and is associated with a favorable outcome in childhood acute lymphoblastic leukemia
- (1996) Blood , vol.88 , pp. 4252-4258
- McLean, T.W.¹ Ringold, S.² Neuberg, D.³ Stegmaier, K.⁴ Tantravahi, R.⁵ Ritz, J.⁶ Koeffler, H.P.⁷ Takeuchi, S.⁸ Janssen, J.W.⁹ Seriu, T.¹⁰ Bartram, C.R.¹¹ Sallan, S.E.¹² Gilliland, D.G.¹³ Golub, T.R.¹⁴

22
- 0031055374
- Case-control study suggests a favorable impact of TEL rearrangement in patients with B-lineage acute lymphoblastic leukemia treated with antimetabolite-based therapy: A Pediatric Oncology Group study
- (1997) Blood , vol.89 , pp. 1143-1146
- Rubnitz, J.E.¹ Shuster, J.J.² Land, V.J.³ Link, M.P.⁴ Pullen, D.J.⁵ Camitta, B.M.⁶ Pui, C.H.⁷ Downing, J.R.⁸ Behm, F.G.⁹

23
- 0031059356
- TEL gene rearrangement in acute lymphoblastic leukemia: A new genetic marker with prognostic significance
- (1997) J Clin Oncol , vol.15 , pp. 1150-1157
- Rubnitz, J.E.¹ Downing, J.R.² Pui, C.H.³ Shurtleff, S.A.⁴ Raimondi, S.C.⁵ Evans, W.E.⁶ Head, D.R.⁷ Crist, W.M.⁸ Rivera, G.K.⁹ Hancock, M.L.¹⁰ Boyett, J.M.¹¹ Buijs, A.¹² Grosveld, G.¹³ Behm, F.G.¹⁴

24
- 0032921624
- Low frequency of TEL-AML1 in relapsed acute lymphoblastic leukemia supports a favorable prognosis for this genetic subgroup
- (1999) Leukemia , vol.13 , pp. 19-21
- Rubnitz, J.E.¹ Behm, F.G.² Wichlan, D.³ Ryan, C.⁴ Sandlund, J.T.⁵ Ribeiro, R.C.⁶ Rivera, G.K.⁷ Hancock, M.L.⁸ Relling, M.V.⁹ Evans, W.E.¹⁰ Pui, C.H.¹¹ Downing, J.R.¹²

25
- 0018870416
- Synthesis of methotrexate polyglutamates by bone marrow cells from patients with leukemia and lymphoma
- (1980) Dev Pharmacol Ther , vol.1 , pp. 40-46
- Witte, A.¹ Whitehead, V.M.² Rosenblatt, D.S.³ Vuchich, M.J.⁴

26
- 0020683341
- Methotrexate metabolism by bone marrow cells from patients with leukemia
- (1983) Adv Exp Med Biol , vol.163 , pp. 287-303
- Whitehead, V.M.¹ Rosenblatt, D.S.²

27
- 0023627983
- Methotrexate polyglutamate synthesis in lymphoblasts from children with acute lymphoblastic leukemia
- (1987) Dev Pharmacol Ther , vol.10 , pp. 443-448
- Whitehead, V.M.¹ Rosenblatt, D.S.² Vuchich, M.-J.³ Beaulieu, D.⁴

28
- 0026342183
- Basis for natural resistance to methotrexate in human acute non-lymphocytic leukemia
- (1991) Leuk Res , vol.15 , pp. 1191-1196
- Lin, J.T.¹ Tong, W.P.² Trippett, T.M.³ Niedzwiecki, D.⁴ Tao, Y.⁵ Tan, C.⁶ Steinherz, P.⁷ Schweitzer, B.I.⁸ Bertino, J.R.⁹

29
- 0025302665
- Accumulation of methotrexate and methotrexate polyglutamates in lymphoblasts at diagnosis of childhood acute lymphoblastic leukemia: A pilot prognostic factor analysis
- (1990) Blood , vol.76 , pp. 44-49
- Whitehead, V.M.¹ Rosenblatt, D.S.² Vuchich, M.-J.³ Shuster, J.J.⁴ Witte, A.⁵ Beaulieu, D.⁶

30
- 0030034467
- Accumulation of methotrexate polyglutamates in lymphoblasts is a determinant of antileukemic effects in vivo. A rationale for high-dose methotrexate
- (1996) J Clin Invest , vol.97 , pp. 73-80
- Masson, E.¹ Relling, M.V.² Synold, T.W.³ Liu, Q.⁴ Schuetz, J.D.⁵ Sandlund, J.T.⁶ Pui, C.-H.⁷ Evans, W.E.⁸

31
- 0026658557
- Accumulation of high levels of methotrexate polyglutamates in lymphoblasts from children with hyperdiploid (>50 chromosomes) B-lineage acute lymphoblastic leukemia: A Pediatric Oncology Group Study
- (1992) Blood , vol.80 , pp. 1316-1323
- Whitehead, V.M.¹ Vuchich, M.-J.² Lauer, S.J.³ Mahoney, D.⁴ Carroll, A.J.⁵ Shuster, J.J.⁶ Esseltine, D.W.⁷ Payment, C.⁸ Look, A.T.⁹ Akabutu, J.¹⁰ Bowen, T.¹¹ Taylor, L.D.¹² Camitta, B.¹³ Pullen, D.¹⁴

32
- 0028063423
- Blast cell methotrexate-polyglutamate accumulation in vivo differs by lineage, ploidy, and methotrexate dose in acute lymphoblastic leukemia
- (1994) J Clin Invest , vol.94 , pp. 1996-2001
- Synold, T.W.¹ Relling, M.V.² Boyett, J.M.³ Rivera, G.K.⁴ Sandlund, J.T.⁵ Mahmoud, H.⁶ Crist, W.M.⁷ Pui, C.-H.⁸ Evans, W.E.⁹

33
- 0032449896
- Accumulation of methotrexate polyglutamates, ploidy and trisomies of both chromosomes 4 and 10 in lymphoblasts from children with B-progenitor cell acute lymphoblastic leukemia: A Pediatric Oncology Group Study
- (1998) Leuk Lymphoma , vol.31 , pp. 507-519
- Whitehead, V.M.¹ Vuchich, M.-J.² Carroll, A.J.³ Lauer, S.J.⁴ Mahoney, D.⁵ Shuster, J.J.⁶ Payment, C.⁷ Koch, P.A.⁸ Akabutu, J.J.⁹ Bowen, T.¹⁰ Kamen, B.A.¹¹ Ravindranath, Y.¹² Emami, A.¹³ Beardsley, G.P.¹⁴ Pullen, D.J.¹⁵ Camitta, B.¹⁶

34
- 0031930089
- Translocations involving chromosome 12p11-13, methotrexate metabolism, and outcome in childhood B-progenitor cell acute lymphoblastic leukemia: A Pediatric Oncology Group study
- (1998) Clin Cancer Res , vol.4 , pp. 183-188
- Whitehead, V.M.¹ Vuchich, M.J.² Cooley, L.³ Lauer, S.J.⁴ Mahoney, D.H.⁵ Shuster, J.J.⁶ Payment, C.⁷ Bernstein, M.L.⁸ Akabutu, J.J.⁹ Bowen, T.¹⁰ Kamen, B.A.¹¹ Watson, M.S.¹² Look, A.T.¹³ Pullen, D.J.¹⁴ Camitta, B.¹⁵

35
- 0025328804
- Poor prognosis of children with pre-B acute lymphoblastic leukemia is associated with the t(1;19)(q23;p13): A Pediatric Oncology Group study
- (1990) Blood , vol.76 , pp. 117-122
- Crist, W.M.¹ Carroll, A.J.² Shuster, J.J.³ Behm, F.G.⁴ Whitehead, M.⁵ Vietti, T.J.⁶ Look, A.T.⁷ Mahoney, D.⁸ Ragab, A.⁹ Pullen, D.J.¹⁰ Land, V.J.¹¹

36
- 0019914176
- Aneuploidy and percentage of S-phase cells determined by flow cytometry correlate with cell phenotype in childhood acute leukemia
- (1982) Blood , vol.60 , pp. 959-967
- Look, A.T.¹ Melvin, S.L.² Williams, S.L.³ Brodeur, G.M.⁴ Dahl, G.V.⁵ Kalwinsky, D.K.⁶ Murphy, S.B.⁷ Mauer, A.M.⁸

37
- 0029100157
- Alternative splicing and genomic structure of the AML1 gene involved in acute myeloid leukemia
- (1995) Nucleic Acids Res , vol.23 , pp. 2762-2769
- Miyoshi, H.¹ Ohita, M.² Shimizu, K.³ Mitani, K.⁴ Hirai, H.⁵ Imai, T.⁶ Yokoyama, K.⁷ Soeda, E.⁸ Ohki, M.⁹

38
- 0004391523
- Nonparametrics: Statistical methods Based on Ranks. Holden-Day: San Francisco, CA
- (1975)
- Lehmann, E.L.¹

39
- 0004149270
- 3rd edn. Irwin Publications: Boston
- (1990) Applied Linear Statistical Models
- Neter, J.¹ Wasserman, W.² Kutner, M.³

40
- 0029147794
- Isolation of a gene encoding a human reduced folate carrier (RFC1) and analysis of its expression in transport-deficient, methotrexate-resistant human breast cancer cells
- (1995) Cancer Res , vol.55 , pp. 3790-3794
- Moscow, J.A.¹ Gong, M.² He, R.³ Sgagias, M.K.⁴ Dixon, K.H.⁵ Anzick, S.L.⁶ Meltzer, P.S.⁷ Cowan, K.H.⁸

41
- 0345291171
- Reduced folate carrier expression in acute lymphoblastic leukemia: A Mechanism for ploidy but not lineage differences in methotrexate accumulation
- (1999) Blood , vol.93 , pp. 1643-1650
- Belkov, V.M.¹ Krynetski, E.Y.² Schuetz, J.D.³ Yanishevski, Y.⁴ Masson, E.⁵ Mathew, S.⁶ Raimondi, S.⁷ Pui, C.H.⁸ Relling, M.V.⁹ Evans, W.E.¹⁰

42
- 0031669954
- Reduced folate carrier gene expression in childhood acute lymphoblastic leukemia: Relationship to immunophenotype and ploidy
- (1998) Clin Cancer Res , vol.4 , pp. 2169-2177
- Zhang, L.¹ Taub, J.W.² Williamson, M.³ Wong, S.C.⁴ Hukku, B.⁵ Pullen, J.⁶ Ravindranath, Y.⁷ Matherly, L.H.⁸

43
- 0026686811
- Expression cloning of a human cDNA encoding folylpoly(gamma-glutamate) synthetase and determination of its primary structure
- (1992) Proc Natl Acad Sci USA , vol.89 , pp. 9151-9155
- Garrow, T.A.¹ Admon, A.² Shane, B.³

44
- 0031868757
- Characterization of human cellular gamma-glutamyl hydrolase
- (1998) Mol Pharmacol , vol.53 , pp. 1040-1046
- Rhee, M.S.¹ Lindau-Shepard, B.² Chave, K.J.³ Galivan, J.⁴ Ryan, T.J.⁵

45
- 0030756226
- Differences in folypolyglutamate synthetase and dihydrofolate reductase expression in human B-lineage versus T-lineage leukemic lymphoblasts: Mechanisms for lineage differences in methotrexate polyglutamylation and cytotoxicity
- (1997) Mol Pharmacol , vol.52 , pp. 155-163
- Galpin, A.J.¹ Schuetz, J.D.² Masson, E.³ Yanishevski, Y.⁴ Synold, T.W.⁵ Barredo, J.C.⁶ Pui, C.H.⁷ Relling, M.V.⁸ Evans, W.E.⁹

46
- 0030634067
- Gamma-glutamyl hydrolase and folypolyglutamate synthetase activities predict polyglutamylation of methotrexate in acute leukemias
- (1997) Oncol Res , vol.9 , pp. 259-263
- Longo, G.S.¹ Gorlick, R.² Tong, W.P.³ Lin, S.⁴ Steinherz, P.⁵ Bertino, J.R.⁶

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.