Aciclovir selects for ganciclovir-cross-resistance of human cytomegalovirus in vitro that is only in part explained by known mutations in the UL97 protein

Journal of Medical Virology

Volumn 65, Issue 1, 2001, Pages 70-76

  Michel, Detlef ^a   Höhn, Simone ^a   Haller, Tobias ^a   Jun, Dou ^b   Mertens, Thomas ^a  

^a UNIVERSITY HOSPITAL ULM   (Germany)

^b MEDICAL SCHOOL OF SOUTHEAST UNIVERSITY   (China)

Author keywords

Antiviral; Cross resistance; Genotyping; Human cytomegalovirus; Prophylaxis

Indexed keywords

ACICLOVIR; CIDOFOVIR; FOSCARNET; GANCICLOVIR; METHIONINE; VALINE;

AMINO ACID SUBSTITUTION; ARTICLE; CROSS RESISTANCE; DOSE RESPONSE; DRUG CHOICE; DRUG SENSITIVITY; GENE MUTATION; GENOTYPE; HUMAN CYTOMEGALOVIRUS; IN VITRO STUDY; NONHUMAN; PHENOTYPE; STRAIN DIFFERENCE; VIRUS ISOLATION;

ACYCLOVIR; ADULT; ANTIVIRAL AGENTS; CELLS, CULTURED; CHILD, PRESCHOOL; CROSS REACTIONS; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; DRUG RESISTANCE, MICROBIAL; DRUG RESISTANCE, MULTIPLE; FEMALE; FIBROBLASTS; GANCICLOVIR; GENOTYPE; HUMANS; INFANT; MALE; MICROBIAL SENSITIVITY TESTS; MUTATION; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR);

EID: 0034906277     PISSN: 01466615     EISSN: None     Source Type: Journal    
DOI: 10.1002/jmv.2003     Document Type: Article

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