-
1
-
-
0028885224
-
A three-nucleotide deletion in the UL97 open reading frame is responsible for the ganciclovir resistance of a human cytomegalovirus clinical isolate
-
Baldanti, F., E. Silini, A. Sarasini, C. L. Talarico, S. C. Stanat, K. K. Biron, M. Furione, F. Bono, G. Palu, and G. Gerna. 1993. A three-nucleotide deletion in the UL97 open reading frame is responsible for the ganciclovir resistance of a human cytomegalovirus clinical isolate. J. Virol. 69:796-800.
-
(1993)
J. Virol.
, vol.69
, pp. 796-800
-
-
Baldanti, F.1
Silini, E.2
Sarasini, A.3
Talarico, C.L.4
Stanat, S.C.5
Biron, K.K.6
Furione, M.7
Bono, F.8
Palu, G.9
Gerna, G.10
-
2
-
-
0024599231
-
Alpha-, beta- and gammaherpesviruses encode a putative phosphotransferase
-
Chee, M. S., G. L. Lawrence, and B. G. Barrell. 1989. Alpha-, beta- and gammaherpesviruses encode a putative phosphotransferase. J. Gen. Virol. 70:1151-1160.
-
(1989)
J. Gen. Virol.
, vol.70
, pp. 1151-1160
-
-
Chee, M.S.1
Lawrence, G.L.2
Barrell, B.G.3
-
3
-
-
0028940302
-
Analysis of the UL97 phosphotransferase coding sequence in clinical cytomegalovirus isolates and identification of mutations conferring ganciclovir resistance
-
Chou, S., A. Erice, M. C. Jordan, G. M. Vercellolti, K. R. Michels, C. L. Talarico, S. C. Stanat, and K. K. Biron. 1995. Analysis of the UL97 phosphotransferase coding sequence in clinical cytomegalovirus isolates and identification of mutations conferring ganciclovir resistance. J. Infect. Dis. 171:576-583.
-
(1995)
J. Infect. Dis.
, vol.171
, pp. 576-583
-
-
Chou, S.1
Erice, A.2
Jordan, M.C.3
Vercellolti, G.M.4
Michels, K.R.5
Talarico, C.L.6
Stanat, S.C.7
Biron, K.K.8
-
4
-
-
0031458254
-
Sequence and transcriptional analysis of the guinea pig cytomegalovirus UL97 homolog
-
Fox, D. S., and M. R Schleiss. 1997. Sequence and transcriptional analysis of the guinea pig cytomegalovirus UL97 homolog. Virus Genes 15:255-264.
-
(1997)
Virus Genes
, vol.15
, pp. 255-264
-
-
Fox, D.S.1
Schleiss, M.R.2
-
5
-
-
0026345394
-
Protein kinase catalytic domain sequence database: Identification of conserved features of primary structure and classification of family members
-
Hanks, S., and A. M. Quinn. 1991. Protein kinase catalytic domain sequence database: identification of conserved features of primary structure and classification of family members. Methods Enzymol. 200:38-81.
-
(1991)
Methods Enzymol.
, vol.200
, pp. 38-81
-
-
Hanks, S.1
Quinn, A.M.2
-
6
-
-
0023885305
-
The protein kinase family: Conserved features and deduced phytogeny of the catalytic domains
-
Hanks, S. K., A. M. Quinn, and T. Hunter. 1988. The protein kinase family: conserved features and deduced phytogeny of the catalytic domains. Science 241:42-52.
-
(1988)
Science
, vol.241
, pp. 42-52
-
-
Hanks, S.K.1
Quinn, A.M.2
Hunter, T.3
-
7
-
-
0029040849
-
Novel mutation in the UL97 gene of a clinical cytomegalovirus strain conferring resistance to ganciclovir
-
Hanson, M., L. C. Preheim, S. Chou, C. L. Talarico, K. K. Biron, and A. Erice. 1995. Novel mutation in the UL97 gene of a clinical cytomegalovirus strain conferring resistance to ganciclovir. Antimicrob. Agents Chemother. 39:1204-1205.
-
(1995)
Antimicrob. Agents Chemother.
, vol.39
, pp. 1204-1205
-
-
Hanson, M.1
Preheim, L.C.2
Chou, S.3
Talarico, C.L.4
Biron, K.K.5
Erice, A.6
-
8
-
-
0031060542
-
The human cytomegalovirus UL97 protein is a protein kinase that autophosphorylates on serines and threonines
-
He, Z., Y. He, Y. Kim, L. Chu, C. Ohmstede, K. K. Biron, and D. M. Coen. 1997. The human cytomegalovirus UL97 protein is a protein kinase that autophosphorylates on serines and threonines. J. Virol. 71:405-411.
-
(1997)
J. Virol.
, vol.71
, pp. 405-411
-
-
He, Z.1
He, Y.2
Kim, Y.3
Chu, L.4
Ohmstede, C.5
Biron, K.K.6
Coen, D.M.7
-
9
-
-
0033524943
-
Crystal structure of the cytoplasmic domain of the type I TGFß receptor in complex with FKBP12
-
Huse, M., Y.-G. Chen, J. Massagué, and J. Kuriyan. 1999. Crystal structure of the cytoplasmic domain of the type I TGFß receptor in complex with FKBP12. Cell 96:425-436.
-
(1999)
Cell
, vol.96
, pp. 425-436
-
-
Huse, M.1
Chen, Y.-G.2
Massagué, J.3
Kuriyan, J.4
-
10
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:681-685.
-
(1970)
Nature
, vol.227
, pp. 681-685
-
-
Laemmli, U.K.1
-
11
-
-
0026664424
-
Human cytomegalovirus UL97 open reading frame encodes a protein that phosphurylates the anti-viral nucleoside analog ganciclovir
-
Littler, E., A. D. Stuart, and M. S. Chee. 1992. Human cytomegalovirus UL97 open reading frame encodes a protein that phosphurylates the anti-viral nucleoside analog ganciclovir. Nature 358:160-162.
-
(1992)
Nature
, vol.358
, pp. 160-162
-
-
Littler, E.1
Stuart, A.D.2
Chee, M.S.3
-
12
-
-
0028271126
-
Mutation in the UL97 open reading frame of human cytomegalovirus strains resistant to ganciclovir
-
Lurain, N. S., L. E. Spafford, and K. D. Thompson. 1994. Mutation in the UL97 open reading frame of human cytomegalovirus strains resistant to ganciclovir. J. Virol. 68:4427-4431.
-
(1994)
J. Virol.
, vol.68
, pp. 4427-4431
-
-
Lurain, N.S.1
Spafford, L.E.2
Thompson, K.D.3
-
13
-
-
0028051525
-
Human cytomegalovirus UL97 kinase confers ganciclovir susceptibility to recombinant vaccinia virus
-
Metzger, C., D. Michel, K. Schneider, A. Lüske, H.-J. Schlicht, and T. Mertens. 1994. Human cytomegalovirus UL97 kinase confers ganciclovir susceptibility to recombinant vaccinia virus. J. Virol. 68:8423-8427.
-
(1994)
J. Virol.
, vol.68
, pp. 8423-8427
-
-
Metzger, C.1
Michel, D.2
Schneider, K.3
Lüske, A.4
Schlicht, H.-J.5
Mertens, T.6
-
14
-
-
0029841220
-
The UL97 gene product of the human cytomegalovirus is an early-late protein with a nuclear localization but is not a nucleoside kinase
-
Michel, D., I. Pavic, A. Zimmermann, E. Haupt, K. Wunderlich, M. Heuschmid, and T. Mertens. 1996. The UL97 gene product of the human cytomegalovirus is an early-late protein with a nuclear localization but is not a nucleoside kinase. J. Virol. 70:6340-6347.
-
(1996)
J. Virol.
, vol.70
, pp. 6340-6347
-
-
Michel, D.1
Pavic, I.2
Zimmermann, A.3
Haupt, E.4
Wunderlich, K.5
Heuschmid, M.6
Mertens, T.7
-
15
-
-
0031695660
-
Functional regions of the human cytomegalovirus protein pUL97 involved in nuclear localization and phosphorylation of ganciclovir and pUL97 itself
-
Michel, D., P. Schaarschmidt, K. Wunderlich, M. Heuschmid, L. Simoncini, D. Mühlberger, A. Zimmermann, I. Pavic, and T. Mertens. 1998. Functional regions of the human cytomegalovirus protein pUL97 involved in nuclear localization and phosphorylation of ganciclovir and pUL97 itself. J. Gen. Virol. 79:2105-2112.
-
(1998)
J. Gen. Virol.
, vol.79
, pp. 2105-2112
-
-
Michel, D.1
Schaarschmidt, P.2
Wunderlich, K.3
Heuschmid, M.4
Simoncini, L.5
Mühlberger, D.6
Zimmermann, A.7
Pavic, I.8
Mertens, T.9
-
16
-
-
0030588936
-
Partial substitution of the functions of the herpes simplex virus 1 UL13 gene by the human cytomegalovirus UL97 gene
-
Ng, T. I., C. Talarico, T. C. Burnette, K. Biron, and B. Roizman. 1996. Partial substitution of the functions of the herpes simplex virus 1 UL13 gene by the human cytomegalovirus UL97 gene. Virology 225:347-358.
-
(1996)
Virology
, vol.225
, pp. 347-358
-
-
Ng, T.I.1
Talarico, C.2
Burnette, T.C.3
Biron, K.4
Roizman, B.5
-
17
-
-
0033033631
-
A recombinant human cytomegalovirus with a large deletion in UL97 has a severe replication deficiency
-
Prichard, M. N., N. Gao, S. Jairath, G. Mulamba, P. Krosky, D. M. Coen, B. O. Parker, and G. S. Pari. 1999. A recombinant human cytomegalovirus with a large deletion in UL97 has a severe replication deficiency. J. Virol. 73:5663-5670.
-
(1999)
J. Virol.
, vol.73
, pp. 5663-5670
-
-
Prichard, M.N.1
Gao, N.2
Jairath, S.3
Mulamba, G.4
Krosky, P.5
Coen, D.M.6
Parker, B.O.7
Pari, G.S.8
-
18
-
-
0004136246
-
-
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
-
Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
-
(1989)
Molecular Cloning: a Laboratory Manual, 2nd Ed.
-
-
Sambrook, J.1
Fritsch, E.F.2
Maniatis, T.3
-
19
-
-
0345281085
-
-
Submitted for publication
-
Simoncini, L., F. Baldanti, D. Michel, M. Heuschmid, A. Zimmermann, P. Schaarschmidt, G. Gerna, and T. Mertens. Mutations in the UL97 ORF found in resistant clinical human cytomegaloviruses differentially reduce ganciclovir (GCV) phosphorylation as determined by vaccinia virus recombinants. Submitted for publication.
-
Mutations in the UL97 ORF Found in Resistant Clinical Human Cytomegaloviruses Differentially Reduce Ganciclovir (GCV) Phosphorylation As Determined by Vaccinia Virus Recombinants
-
-
Simoncini, L.1
Baldanti, F.2
Michel, D.3
Heuschmid, M.4
Zimmermann, A.5
Schaarschmidt, P.6
Gerna, G.7
Mertens, T.8
-
20
-
-
0026720227
-
A protein kinase homologue controls phosphorylation of ganciclovir in human cytomegalovirus-infected cells
-
Sullivan, V., C. L. Talarico, S. C. Stanat, M. Davis, D. M. Coen, and K. K. Biron. 1992. A protein kinase homologue controls phosphorylation of ganciclovir in human cytomegalovirus-infected cells. Nature 358:162-164.
-
(1992)
Nature
, vol.358
, pp. 162-164
-
-
Sullivan, V.1
Talarico, C.L.2
Stanat, S.C.3
Davis, M.4
Coen, D.M.5
Biron, K.K.6
-
21
-
-
0032518234
-
Characterization of rhesus cytomegalovirus genes associated with anti-viral susceptibility
-
Swanson, R., E. Bergquam, and S. W. Wong. 1998. Characterization of rhesus cytomegalovirus genes associated with anti-viral susceptibility. Virology 240:338-348.
-
(1998)
Virology
, vol.240
, pp. 338-348
-
-
Swanson, R.1
Bergquam, E.2
Wong, S.W.3
-
22
-
-
0030955930
-
The human cytomegalovirus UL97 protein is phosphorylated and a component of virions
-
Van Zeijl, M., J. Fairhurst, E. Z. Baum, L. Sun, and T. R. Jones. 1997. The human cytomegalovirus UL97 protein is phosphorylated and a component of virions. Virology 231:72-80.
-
(1997)
Virology
, vol.231
, pp. 72-80
-
-
Van Zeijl, M.1
Fairhurst, J.2
Baum, E.Z.3
Sun, L.4
Jones, T.R.5
-
23
-
-
0031812811
-
Characterization of the human cytomegalovirus UL97 gene product as a virion-associated protein kinase
-
Wolf, D. G., A. Honigman, J. Lazarovits, E. Tavor, and A. Panel. 1998. Characterization of the human cytomegalovirus UL97 gene product as a virion-associated protein kinase. Arch. Virol. 143:1223-1232.
-
(1998)
Arch. Virol.
, vol.143
, pp. 1223-1232
-
-
Wolf, D.G.1
Honigman, A.2
Lazarovits, J.3
Tavor, E.4
Panel, A.5
-
24
-
-
0028859327
-
Mutations in human cytomegalovirus UL97 gene confer clinical resistance to ganciclovir and can be detected directly in patient plasma
-
Wolf, D. G., I. L. Smith, D. J. Lee, W. R. Freeman, M. Flores-Aguilar, and S. A. Spector. 1995. Mutations in human cytomegalovirus UL97 gene confer clinical resistance to ganciclovir and can be detected directly in patient plasma. J. Clin. Investig. 95:257-263.
-
(1995)
J. Clin. Investig.
, vol.95
, pp. 257-263
-
-
Wolf, D.G.1
Smith, I.L.2
Lee, D.J.3
Freeman, W.R.4
Flores-Aguilar, M.5
Spector, S.A.6
-
25
-
-
0030782932
-
Phosphorylation of aciclovir, ganciclovir, penciclovir and S2242 by the cytomegalovirus UL97 protein: A quantitative analysis using recombinant vaccinia viruses
-
Zimmermann, A., D. Michel, I. Pavic, W. Hampl, A. Lüske, J. Neyts, E. De Clercq, and T. Mertens. 1997. Phosphorylation of aciclovir, ganciclovir, penciclovir and S2242 by the cytomegalovirus UL97 protein: a quantitative analysis using recombinant vaccinia viruses. Antivir. Res. 36:35-42.
-
(1997)
Antivir. Res.
, vol.36
, pp. 35-42
-
-
Zimmermann, A.1
Michel, D.2
Pavic, I.3
Hampl, W.4
Lüske, A.5
Neyts, J.6
De Clercq, E.7
Mertens, T.8
|