Pyridinyl imidazole inhibitor SB203580 activates p44/42 mitogen-activated protein kinase and induces the differentiation of human myeloid leukemia cells

Leukemia Research

Volumn 25, Issue 9, 2001, Pages 813-820

  Ishii, Yuki ^a,b   Sakai, Shingo ^b   Honma, Yoshio ^a  

^a SAITAMA CANCER CENTER   (Japan)

^b UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Differentiation; Erk2; Kinase inhibitor; Leukemia cells; Mitogen activated protein kinase; P38 kinase; SB203580

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; LYSOZYME; MITOGEN ACTIVATED PROTEIN KINASE; NITROBLUE TETRAZOLIUM; SYNAPTOPHYSIN;

ARTICLE; CELL DIFFERENTIATION; CELL STRUCTURE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GROWTH INHIBITION; HUMAN; HUMAN CELL; LEUKEMIA CELL; LEUKEMIA CELL LINE; MYELOID LEUKEMIA; PRIORITY JOURNAL;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL DIFFERENTIATION; CELL DIVISION; ENZYME ACTIVATION; HL-60 CELLS; HUMANS; IMIDAZOLES; LEUKEMIA, MYELOID; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRIDINES; TUMOR CELLS, CULTURED;

EID: 0034905018     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0145-2126(01)00026-1     Document Type: Article

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