Cellular responses in chickens treated with IFN-α orally or inoculated with recombinant Marek's disease virus expressing IFN-α

Journal of Interferon and Cytokine Research

Volumn 21, Issue 5, 2001, Pages 287-296

  Jarosinski, K W ^a   Jia, W ^a,b   Sekellick, M J ^c   Marcus, P I ^c   Schat, K A ^a  

^a Department of Obstetrics Gynecology   (United States)

^b Intervet/Schering Plough Animal Health   (United States)

^c UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; RECOMBINANT ALPHA INTERFERON;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AVIAN LYMPHOMATOSIS HERPETOVIRUS; CELL CULTURE; CHICKEN; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; DRUG EFFECT; EMBRYO CELL; INOCULATION; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TECHNIQUE; VIRUS INHIBITION; VIRUS RECOMBINANT; VIRUS REPLICATION; VIRUS STRAIN; VIRUS VIRULENCE;

ADMINISTRATION, ORAL; ANIMALS; ANTIVIRAL AGENTS; CHICKENS; CLONING, MOLECULAR; CYTOTOXICITY, IMMUNOLOGIC; DRINKING; HERPESVIRUS 2, GALLID; INTERFERON TYPE I, RECOMBINANT; INTERFERON-ALPHA; KILLER CELLS, NATURAL; MAREK DISEASE; VACCINES, SYNTHETIC; VIRAL VACCINES; VIRUS REPLICATION;

EID: 0034904911     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/107999001300177475     Document Type: Article

References (56)

1. Induction of bystander T cell proliferation by viruses and type I interferon in vivo
2. Interferon induces natural killer cell blastogenesis in vivo
3. Increase in NK cell number and turnover rate during acute viral infection
4. Blastogenesis of natural killer cells during viral infection in vivo
5. Cell-mediated cytotoxicity against virus-infected target cells in humans. II. Interferon induction and activation of natural killer cells
6. Enhanced NK cell activity in mice injected with interferon and interferon inducers
7. Spontaneous cell-mediated cytotoxicity in humans: Role of interferon and immunoglobulins
8. Initial and innate responses to viral infections - Pattern setting in immunity or disease
9. Natural killer cells in antiviral defense: Function and regulation by innate cytokines
10. Interferon action on avian viruses. I. Oral administration of chicken interferon-α ameliorates Newcastle disease
11. Recombinant chicken interferon: A potent antiviral agent that lacks intrinsic macrophage activating factor activity
12. Cloning and expression of the chicken interferon-γ gene
13. Biological properties of recombinant chicken interferon-γ
14. In vitro effects of recombinant chicken interferon-γ on immune cells
15. Protective effects of type I and type II interferons toward Rous sarcoma virus-induced tumors in chickens
16. Recombinant interleukin 2 as an adjuvant for vaccine-induced protection. Immunization of guinea pigs with herpes simplex virus subunit vaccines
17. Interleukin 2 acts as an adjuvant to increase the potency of inactivated rabies virus vaccine
18. The immune response against foot-and-mouth disease virus: Influence of the T lymphocyte growth factors IL-1 and IL-2 on the murine humoral response in vivo
19. Cytokines as immunological adjuvants
20. Cytokines in health and disease
21. Immunopotentiation of bovine respiratory disease virus vaccines by interleukin-1β and interleukin 2
22. Influence of recombinant bovine interleukin-1β and interleukin-2 in pigs vaccinated and challenged with Streptococcus suis
23. BHV-1 glycoprotein 1 and recombinant interleukin 1β efficiently elicit mucosal IgA response
24. Recombinant fowlpox viruses coexpressing chicken type I IFN and Newcastle disease virus HN and F genes: Influence of IFN on protective efficacy and humoral responses of chickens following in ovo or post-hatch administration of recombinant viruses
25. Delivery of avian cytokines by adenovirus vectors
26. Low-dose oral type I interferons reduce early virus replication of murine cytomegalovirus in vivo
27. Modulation of peripheral leukocyte counts in mice by oral administration of interferons
28. Orally administered interferons exert their white blood cell suppressive effects via a novel mechanism
29. Systemic effects of orally administered interferons and interleukin-2
30. Cytokine therapy: A natural alternative for disease control
31. Avian cytokines - The natural approach to therapeutics
32. Embryo vaccination of turkeys against Newcastle disease infection with recombinant fowlpox virus constructs containing interferons as adjuvants
33. Increased virulence of Marek's disease virus field isolates
34. Attenuated revertant serotype 1 Marek's disease viruses: Safety and protective efficacy
35. Characterization of two highly oncogenic strains of Marek's disease virus
36. Cell-culture methods
37. Chicken interferon gene: Cloning, expression and analysis
38. Open reading frame L1 of Marek's disease herpesvirus is not essential for in vitro and in vivo virus replication and establishment of latency
39. Induction of high titer chicken interferon
40. Chicken interferon types I and II enhance synergistically the antiviral state and nitric oxide secretion
41. Enhancement of natural killer cell activity by Marek's disease vaccines
42. Natural killer cell activity in chickens: Target cell analysis and effect of antithymocyte serum on effector cells
43. In vitro cytotoxicity of spleen lymphocytes against Marek's disease tumor cells: Induction by SB-1, an apparently non-oncogenic Marek's disease virus
44. Comparative natural killer cell activities of thymic, bursal, splenic and intestinal intraepithelial lymphocytes of chickens
45. Transient resistance of influenza virus to interferon action attributed to random multiple packaging and activity of NS genes
46. Interferon induction by viruses. XX. Acid-labile interferon accounts for the antiviral effect induced by poly(rI):poly(rC) in primary chick embryo cells
47. Impairment of T and B cell development by treatment with a type I interferon
48. - thymocytes
49. Characterization of avian natural killer cells and their intracellular CD3 protein complex
50. Role of chicken IL-2 on γδ T-cells and Eimeria acervulina-induced changes in intestinal IL-2 mRNA expression and γδ T-cells
51. 2-microglobulin is involved in thymus colonization of chicken embryos
52. NK cell trafficking and cytokine expression in splenic compartments after IFN induction and viral infection
53. Orally administered interferons suppress bone marrow function
54. Effect of native chicken interferon on MDV replication
55. Stages of Marek's disease virus latency defined by variable sensitivity to interferon modulation of viral antigen expression
56. Natural killer cell activity in chickens exposed to Marek's disease virus: Inhibition of activity in susceptible chickens and enhancement of activity in resistant and vaccinated chickens