A-type K+ current mediated by the Kv4 channel regulates the generation of action potential in developing cerebellar granule cells

Journal of Neuroscience

Volumn 20, Issue 11, 2000, Pages 4145-4155

  Shibata, Riichi ^a,b   Nakahira, Kensuke ^a,c   Shibasaki, Koji ^a,b   Wakazono, Yoshihiko ^a,d   Imoto, Keiji ^a,b   Ikenaka, Kazuhiro ^a,b  

^a NATIONAL INSTITUTES OF NATURAL SCIENCES   (Japan)

^b GRADUATE UNIVERSITY FOR ADVANCED STUDIES   (Japan)

^c NATIONAL INSTITUTE FOR BASIC BIOLOGY   (Japan)

^d HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

A type current; Action potential; Dominant negative; Fast spike latency; Kv4.2; Microexplant culture; Transfection; Whole cell patch clamp

Indexed keywords

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; BRAIN DEVELOPMENT; CEREBELLUM; GRANULE CELL; MOUSE; NERVE CELL DIFFERENTIATION; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL;

EID: 0034212603     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.20-11-04145.2000     Document Type: Article

References (44)

1. Arhem P, Johansson S (1989) A model for the fast 4-aminopyridine effects on amphibian myelinated nerve fibres. A study based on voltage-clamp experiments. Acta Physiol Scand 137:53-61.
2. + channel. Neuron 7:471-483.
3. Bardoni R, Belluzzi O (1993) Kinetic study and numerical reconstruction of A-type current in granule cells of rat cerebellar slices. J Neurophysiol 69:2222-2231.
4. Belluzzi O, Sacchi O, Wanke E (1985) A fast transient outward current in the rat sympathetic neurone studied under voltage-clamp conditions. J Physiol (Lond) 358:91-108.
5. Campbell DL, Qu Y, Rasmusson RL, Strauss HC (1993) The calcium-independent transient outward potassium current in isolated ferret right ventricular myocytes. II. Closed state reverse use-dependent block by 4-aminopyridine. J Gen Physiol 101:603-626.
6. + current in adult rat ventricular myocytes. J Pharmacol Exp Ther 265:1450-1459.
7. Choquet D, Korn H (1992) Mechanism of 4-aminopyridine action on voltage-gated potassium channels in lymphocytes. J Gen Physiol 99:217-240.
8. Cull-Candy SG, Marshall CG, Ogden D (1989) Voltage-activated membrane currents in rat cerebellar granule neurones. J Physiol (Lond) 414:179-199.
9. 2+ action potentials in immature rat cerebellar granule cells in situ. J Neurophysiol 78:1631-1642.
10. D'Angelo E, De Filippi G, Rossi P, Taglietti V (1998) Ionic mechanism of electroresponsiveness in cerebellar granule cells implicates the action of a persistent sodium current. J Neurophysiol 80:493-503.
11. Davies NW, Pettit AI, Agarwal R, Standen NB (1991) The flickery block of ATP-dependent potassium channels of skeletal muscle by internal 4-aminopyridine. Pflügers Arch 419:25-31.
12. Downen M, Belkowski S, Knowles H, Cardillo M, Prystowsky MB (1999) Developmental expression of voltage-gated potassium channel β subunits. Brain Res Dev Brain Res 117:71-80.
13. + current influences excitability in acutely isolated vasopressin and oxytocin neurones of rat hypothalamus. J Physiol (Lond) 511:423-432.
14. Gorter JA, Aronica E, Hack NJ, Balazs R, Wadman WJ (1995) Development of voltage-activated potassium currents in cultured cerebellar granule neurons under different growth conditions. J Neurophysiol 74:298-306.
15. Heinemann SH, Rettig J, Graack HR, Pongs O (1996) Functional characterization of Kv channel β-subunits from rat brain. J Physiol (Lond) 493:625-633.
16. + channels in dendrites of hippocampal CA1 pyramidal neurons by activation of PKA and PKC. J Neurosci 18:3521-3528.
17. + channel regulation of signal propagation in dendrites of hippocampal pyramidal neurons. Nature 387:869-875.
18. Johns DC, Nuss HB, Marban E (1997) Suppression of neuronal and cardiac transient outward currents by viral gene transfer of dominant-negative Kv4.2 constructs. J Biol Chem 272:31598-31603.
19. Kanold PO, Manis PB (1999) Transient potassium currents regulate the discharge patterns of dorsal cochlear nucleus pyramidal cells. J Neurosci 19:2195-2208.
20. + current in rat melanotrophs. J Physiol (Lond) 431:515-528.
21. Keros S, McBain CJ (1997) Arachidonic acid inhibits transient potassium currents and broadens action potentials during electrographic seizures in hippocampal pyramidal and inhibitory interneurons. J Neurosci 17:3476-3487.
22. + channels of fast-spiking interneurons and pyramidal neurons of rat hippocampus. J Neurosci 18:8111-8125.
23. Nagata I, Nakatsuji N (1990) Granule cell behavior on laminin in cerebellar microexpiant cultures. Brain Res Dev Brain Res 52:63-73.
24. Numann RE, Wadman WJ, Wong RK (1987) Outward currents of single hippocampal cells obtained from the adult guinea-pig. J Physiol (Lond) 393:331-353.
25. Ramoa AS, McCormick DA (1994) Developmental changes in electrophysiological properties of LGNd neurons during reorganization of retinogeniculate connections. J Neurosci 14:2089-2097.
26. + channels altered by presence of β-subunit. Nature 369:289-294.
27. Rogawski MA, Bcinfcld MC, Hays SE, Hokfelt T, Skirboll LR (1985) Cholecystokinin and cultured spinal neurons. Immunohistochemistry, receptor binding, and neurophysiology. Ann N Y Acad Sci 448:403-412.
28. Rossi P, De Filippi G, Armano S, Taglietti V, D'Angelo E (1998) The weaver mutation causes a loss of inward rectifier current regulation in premigratory granule cells of the mouse cerebellum. J Neurosci 18:3537-3547.
29. Rudy B, Hoger JH, Lester HA, Davidson N (1988) At least two mRNA species contribute to the properties of rat brain A-type potassium channels expressed in Xenopus oocytes. Neuron 1:649-658.
30. Schroter KH, Ruppersberg JP, Wunder F, Rettig J, Stocker M, Pongs O (1991) Cloning and functional expression of a TEA-sensitive A-type potassium channel from rat brain. FEBS Lett 278:211-216.
31. + (A-type) currents in rat brain. J Neurophysiol 79:1081-1091.
32. Serodio P, Kentros C, Rudy B (1994) Identification of molecular components of A-type channels activating at subthreshold potentials. J Neurophysiol 72:1516-1529.
33. + channels operating at subthreshold potentials with unique expression in heart and brain. J Neurophysiol 75:2174-2179.
34. Sewing S, Roeper J, Pongs O (1996) Kv β1 subunit binding specific for shaker-related potassium channel a subunits. Neuron 16:455-463.
35. + channel proteins in rat central neurons. Neuron 9:271-284.
36. Shibata R, Wakazono Y, Nakahira K, Trimmer JS, Ikenaka K (1999) Expression of Kv3.1 and Kv4.2 genes in developing cerebellar granule cells. Dev Neurosci 21:87-93.
37. Song WJ, Tkatch T, Baranauskas G, Ichinohe N, Kitai ST, Surmeier DJ (1998) Somatodendritic depolarization-activated potassium currents in rat neostriatal cholinergic interneurons are predominantly of the A type and attributable to coexpression of Kv4.2 and Kv4.1 subunits. J Neurosci 18:3124-3137.
38. Spitzer NC (1995) Spontaneous activity: functions of calcium transients in neuronal differentiation. Perspect Dev Neurobiol 2:379-386.
39. + current in cerebellar granule cells. Proc Natl Acad Sci USA 93:11191-11195.
40. Thompson S (1982) Aminopyridine block of transient potassium current. J Gen Physiol 80:1-18.
41. + channel a subunit. FEBS Lett 400:215-220.
42. + currents in developing cerebellar granule cells in vitro. Neurosci Res 29:291-301.
43. Wang Y, Strahlendorf JC, Strahlendorf HK (1991) A transient voltage-dependent outward potassium current in mammalian cerebellar Purkinje cells. Brain Res 567:153-158.
44. Yeh JZ, Oxford GS, Wu CH, Narahashi T (1976) Dynamics of aminopyridine block of potassium channels in squid axon membrane. J Gen Physiol 68:519-535.