Effects of the phytoestrogen coumestrol on locomotor and fear-related behaviors in female mice

Hormones and Behavior

Volumn 40, Issue 1, 2001, Pages 65-76

  Garey, Joan ^a   Morgan, Maria A ^a   Frohlich, Jonathan ^a   McEwen, Bruce S ^a   Pfaff, Donald W ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Behavior; Coumestrol; Estrogen; Fear; Locomotor; Mice; Open field; Phytoestrogen

Indexed keywords

COUMESTROL; ISOFLAVONOID; PHYTOESTROGEN;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FEAR; LEARNING; LIGHT DARK CYCLE; MOTOR CONTROL; MOUSE; MUSCULOSKELETAL SYSTEM; NONHUMAN; OPEN FIELD BEHAVIOR; PHYSICAL ACTIVITY; POSTMENOPAUSE; PRIORITY JOURNAL; SCREENING; SILICONE PROSTHESIS;

EID: 0034900562     PISSN: 0018506X     EISSN: None     Source Type: Journal    
DOI: 10.1006/hbeh.2001.1660     Document Type: Article

References (43)

1. Sexual behavior responses of the ovariectomized ewe to estradiol benzoate, and their persistent reduction after exposure to phytoestrogens
2. A changed responsiveness to oestrogen in ewes with clover disease
3. Sexual behaviour of ewes with clover disease treated repeatedly with oestradiol benzoate or testosterone propionate after ovariectomy
4. Health potential of soy isoflavones for menopausal women
5. Pharmacological profile of apigenin, a flavonoid isolated from Matricaria chamomilla
6. Acquisition of fear conditioning in rats requires the synthesis of mRNA in the amygdala
7. Estrogenic activity of flavonoids in mice. The importance of estrogen receptor distribution, metabolism and bioavailability
8. Regulation of human estrogen receptor by phytoestrogens in yeast and human cells
9. The potential of soybean phytoestrogens for postmenopausal hormone replacement therapy
10. Behavioral phenotyping of transgenic and knockout mice: Experimental design and evaluation of general health, sensory functions, motor abilities, and specific behavioral tests
11. Effects of estradiol on sexual receptivity, wheel-running behavior, and vaginal estrus in virgin prairie voles
12. Estradiol concentration and the regulation of locomotor activity
13. Influence of the estrous cycle, ovariectomy and estradiol replacement upon the acquisition of conditioned avoidance responses in rats
14. Preoptic implants of estradiol increase wheel running but not the open field activity of female rats
15. Why we think plasticity underlying Pavlovian fear conditioning occurs in the basolateral amygdala
16. Statistical analysis of measures of arousal in ovariectomized female mice
17. The estrogen receptor β-isoform (ERβ) of the human estrogen receptor modulates ERα transcriptional activity and is a key regulator of the cellular response to estrogens and antiestrogens
18. Interaction of flavones from the roots of Scutellaria baicalensis with the benzodiazepine site
19. Photoperiodic and pineal influences on estrogen-stimulated behaviors in female Syrian hamsters
20. Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor β
21. Cloning of a novel estrogen receptor expressed in rat prostate and ovary
22. Phytoestrogens and mammalian reproduction
23. Forage plant estrogens
24. Differential expression of EGR-1 mRNA in the amygdala following diazepam in contextual fear conditioning
25. In vitro bioassays of non-steroidal phytoestrogens
26. Binding of phyto-oestrogen and oestradiol-17β by cytoplasmic receptors in the pituitary gland and hypothalamus of the ewe
27. Chrysin (5,7-di-OH-flavone), a naturally-occurring ligand for benzodiazepine receptors, with anticonvulsant properties
28. Overview - Flavonoids: A new family of benzodiazepine receptor ligands
29. Effects of the estrous cycle and ovarian hormones on behavioral indices of anxiety in female rats
30. Endocrine modulators in the food chain and environment
31. Influences of estrogen and/or progesterone on some dopamine related behavior in rats
32. Regulation of estrogen receptor beta mRNA in the brain: Opposite effects of 17β-estradiol and the phytoestrogen, coumestrol
33. Animal behavior and internal drives
34. Anxiolytic natural and synthetic flavonoid ligands of the central benzodiazepine receptor have no effect on memory tasks in rats
35. Corticosterone delivery to the amydala increases corticotropin-releasing factor mRNA in the central amygdaloid nucleus and anxiety-like behavior
36. Comparative distribution of estrogen receptor α and β mRNA in the rat central nervous system
37. Ovarian steroid deprivation results in a reversible learning impairment and compromised cholinergic function in female Sprague-Dawley rats
38. The relation between "spontaneous" activity and oestrous cycle in the white rat
39. Dietary estrogens: A biologically active background for estrogen action
40. Effects of a phytoestrogen diet on estrogen-dependent reproductive processes in immature female rats
41. The ovarian hormones and spontaneous running activity in the female rat