Evidence for a role for both the adenosine A1 and A3 receptors in protection of isolated human atrial muscle against simulated ischaemia

Cardiovascular Research

Volumn 36, Issue 1, 1997, Pages 52-59

  Carr, Cornelia S ^a   Hill, Roger J ^a   Masamune, Hiroko ^a   Kennedy, Scott P ^b   Knight, Delvin R ^a   Tracey, W Ross ^a   Yellon, Derek M ^a  

^a UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

^b PFIZER INC   (United States)

Author keywords

Adenosine A1 receptor; Adenosine A3 receptor; Human atrium; Ischemic preconditioning

Indexed keywords

8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE A1 RECEPTOR; ADENOSINE A1 RECEPTOR AGONIST; ADENOSINE A1 RECEPTOR ANTAGONIST; ADENOSINE A3 RECEPTOR; ADENOSINE RECEPTOR STIMULATING AGENT;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; HEART ATRIUM MUSCLE; HEART MUSCLE CONTRACTILITY; HEART MUSCLE ISCHEMIA; HEART MUSCLE OXYGEN CONSUMPTION; HEART PROTECTION; HUMAN; HUMAN TISSUE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REOXYGENATION;

ADENOSINE; DINUCLEOSIDE PHOSPHATES; HEART ATRIA; HUMANS; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MODELS, BIOLOGICAL; MYOCARDIAL CONTRACTION; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION; RECEPTOR, ADENOSINE A3; RECEPTORS, PURINERGIC P1; XANTHINES;

EID: 0030665468     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(97)00160-0     Document Type: Article

References (43)

1. Murry CE, Jennings RB, Reimer KA. Preconditioning with ischaemia: a delay of lethal cell injury in ischaemic myocardium. Circulation 1986;74(5):1124-1136.
2. Downey JM, Liu GS, Thornton JD. Adenosine and the anti-infarct effects of preconditioning. Cardiovasc Res 1993;27:3-8.
3. Asimakis GK, Inners-McBride K, Medelin G, Conti VR. Ischaemic preconditioning attenuates acidosis and postischaemic dysfunction in isolated rat heart. Am J Physiol 1992;32(3):H887-H892.
4. Murry CE, Richard VJ, Reimer KA, Jennings RB. Ischaemic preconditioning slows energy metabolism and delays ultrastructural damage during a sustained ischaemic episode. Circ Res 1990;66:913-931.
5. Kida M, Yokota R, Tanaka M. Effect of ischaemic preconditioning on energy metabolism during short sustained ischaemia and reperfusion in pig hearts. J Mol Cell Cardiol 1992;24(Suppl II):II-S.5.
6. Alkhulaifi AM, Pugsley WP, Yellon DM. The influence of the time period between preconditioning ischaemia and prolonged ischaemic insult on myocardial protection. Cardioscience 1993;4:163-169.
7. Auchampach J, Grover G, Gross G. Blockade of ischaemic preconditioning in dogs by the novel ATP-dependent potassium channel antagonist sodium 5-hydroxydecanoate. Cardiovasc Res 1992;26:1054-1062.
8. Gross GJ, Auchampach JA. Blockade of ATP-sensitive potassium channels prevents myocardial preconditioning in dogs. Circ Res 1992;70:223-233.
9. Speechly-Dick ME, Grover GJ, Yellon DM. Does ischaemic preconditioning in the human involve Protein Kinase C and the ATP-dependent K+ channel? Studies of contractile function following simulated ischaemia in an atrial in vitro model. Circ Res 1995;77(5):1030-1035.
10. Thornton J, Liu G, Olsson R, Downey J. Intravenous pretreatment with A1-selective adenosine analogues protects the heart against infarction. Circulation 1992;85(2):659-665.
11. Auchampach J, Gross G. Adenosine A1 receptors, KATP channels, and ischaemic preconditioning on dogs. Am J Physiol 1993;264:H1327-H1336.
12. Mizumura T, Auchampach J, Linden J, Bruns R, Gross G. PD81/723, an allosteric enhancer of the A1 adenosine receptor, lowers the threshold for ischaemic preconditioning. Circ Res 1996;79:415-423.
13. Van Winkle D, Chien G, Wolff R, Soifer B, Davis R. Intracoronary infusion of R-phenylisopropyl adenosine prior to ischaemia/reperfusion reduces myocardial infarct size in swine (abstract). Circulation 1992;86(Suppl I):I-213.
14. Ganote C, Armstrong S, Downey J. Adenosine and A1 selective agonists offer minimal protection against ischaemic injury to isolated rat cardiomyocytes. Cardiovasc Res 1993;27:1670-1676.
15. Cave A, Collis C, Downey J, Hearse D. Improved functional recovery by ischaemic preconditioning is not mediated by adenosine in the globally ischaemic rat heart. Cardiovasc Res 1993;27:663-668.
16. Liu GS, Thornton J, Van Winkle DM, et al. Protection against infarction afforded by preconditioning is mediated by A1 adenosine receptors in the rabbit heart. Circulation 1991;84:350-356.
17. Liu G, Richards S, Olsson R, et al. Evidence that the adenosine A3 receptor may mediate the protection afforded by preconditioning in the isolated rabbit heart. Cardiovasc Res 1994;28:1057-1061.
18. Armstrong S, Ganote C. Adenosine receptor specificity in preconditioning of isolated rabbit cardiomyocytes: evidence of A3 receptor involvement. Cardiovasc Res 1994;28:1049-1056.
19. Armstrong S, Ganote C. In vitro ischaemic preconditioning of isolated rabbit cardiomyocytes: effects of selective adenosine receptor blockade and calphostin C. Cardiovasc Res 1995;29:647-652.
20. Strickler J, Jacobson K, Liang B. Direct preconditioning of cultured chick ventricular myocytes, novel functions of cardiac adenosine A2a and A3 receptors. J Clin Invest 1996;98:1773-1779.
21. Ytrehus K, Liu Y, Downey J. Preconditioning protects ischaemic rabbit myocardium by protein kinase C activation. Am J Physiol 1994;266:H1145-H1152.
22. Speechly-Dick M, Mocanu M, Yellon D, Protein kinase C. Its role in ischaemic preconditioning in the rat. Circ Res 1994;75:586-590.
23. Hu K, Duan D, Gui-Rong L, Nattel S. Protein kinase C activates ATP-sensitive K current in human and rabbit ventricular myocytes. Circ Res 1996;78:492-498.
24. Schulz R, Rose J, Heusch G. Involvement of activation of ATP-dependent potassium channels in ischaemic preconditioning in swine. Am J Physiol 1994;267:H1341-H1352.
25. Liu Y, Downey JM. Ischaemic preconditioning protects against infarction in rat heart. Am J Physiol 1992;263:H1107-H1112.
26. Grover G, Dzwonczyk S, Sleph P, Sargent C. The ATP-sensitive potassium channel blocker glibenclamide (Glyburide) does not abolish preconditioning in isolated ischaemic rat hearts. J Pharmacol Exp Ther 1993;265:559-564.
27. Thornton J, Thornton C, Sterling D, Downey J. Blockade of ATP-sensitive potassium channels increases infarct size but does not prevent preconditioning in rabbit hearts. Circ Res 1993;72:44-49.
28. Toombs C, Moore T, Shebuski R. Limitation of infarct size in the rabbit by ischaemic preconditioning is reversible with glibenclamide. Cardiovasc Res 1993;27:617-622.
29. Ikonomidis J, Shirai T, Weisel R, Mickle D. Human cardiomyocyte preconditioning is adenosine A1 receptor dependent. Circulation 1994;90:I-477.
30. Walker D, Walker J, Pugsley W, Pattison C, Yellon D. Preconditioning in isolated superfused human muscle. J Mol Cell Cardiol 1995;27:1349-1357.
31. Tomai F, Crea F, Gaspardone A, et al. Effects of A1 adenosine receptor blockade by bamiphylline on ischaemic preconditioning during coronary angioplasty. Eur Heart J 1996;17:846-853.
32. + channel blocker. Circulation 1994;90(2):700-705.
33. Tracey W, Magee W, Masamune H, et al. Selective adenosine A3 receptor stimulation reduces ischaemic myocardial injury in the rabbit heart. Cardiovasc Res 1997;33:410-415.
34. Hill R, Oleynek J, Hoth C, et al. Cloning expression and pharmacological characterization of rabbit adenosine A1 and A3 receptors. J Pharmacol Exp Ther 1997;280:122-128.
35. Cheng Y, Prusoff W. Relationship between the inhibition constant (Ki) and the concentration of inhibitor that causes 50 percent inhibition (IC50) of an enzyme reaction. Biochem Pharmacol 1973;22:3099-3108.
36. Li Y, Kloner EA. The cardioprotective effects of ischaemic 'preconditioning' are not mediated by adenosine receptors in rat hearts. Circulation 1993;87:1642-1648.
37. Rice P, Armstrong S, Ganote C. Concentration-response relationships for adenosine agonists during preconditioning of rabbit cardiomyocytes. J Mol Cell Cardiol 1996;28:1355-1365.
38. Salvatore C, Jacobson M, Taylor H, Linden J, Johnson R. Molecular cloning and characterization of the human A3 adenosine receptor. Proc Natl Acad Sci USA 1993;90(21):10365-10369.
39. Sajjadi F, Firestein G. cDNA cloning and sequence analysis of the human A3 adenosine receptor. Biochim Biophys Acta 1993;1179:105-107.
40. Zhou Q, Li C, Olah M, Johnson R, Stiles G, Civelli O. Molecular cloning and charaterization of an adenosine receptor: the A3 adenosine receptor. Proc Natl Acad Sci USA 1992;89:7432-7436.
41. Ovize M, Przyklenk K, Hale S, Kloner R. Preconditioning does not attenuate myocardial stunning. Circulation 1992;85:2247-2254.
42. Jenkins D, Pugsley W, Yellon D. Ischaemic preconditioning in a model of global ischaemia: infarct size limitation, but no reduction of stunning. J Mol Cell Cardiol 1995;27:1623-1632.
43. Walker D, Marber M, Walker J, Yellon D. Preconditioning in isolated superfused rabbit papillary muscles. Am J Physiol 1994;266:H1534-H1540.