Wnt signaling in human development: Beta-catenin nuclear translocation in fetal lung, kidney, placenta, capillaries, adrenal, and cartilage

Pediatric and Developmental Pathology

Volumn 4, Issue 4, 2001, Pages 351-357

  Eberhart, Charles G ^a   Argani, Pedram ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Beta catenin; Development; Immunohistochemistry; Wnt

Indexed keywords

BETA CATENIN; WNT PROTEIN;

ADRENAL GLAND; ARTICLE; CAPILLARY; CARTILAGE; EMBRYO DEVELOPMENT; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KIDNEY; LUNG; PLACENTA; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION; TISSUE PREPARATION;

ADRENAL GLANDS; ADULT; BETA CATENIN; CAPILLARIES; CARTILAGE; CELL NUCLEUS; CYTOSKELETAL PROTEINS; EMBRYONIC AND FETAL DEVELOPMENT; FEMALE; GESTATIONAL AGE; HUMANS; IMMUNOENZYME TECHNIQUES; INFANT; KIDNEY; LUNG; MALE; PLACENTA; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION; TRANS-ACTIVATORS; WNT PROTEINS; ZEBRAFISH PROTEINS;

EID: 0034894122     PISSN: 10935266     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10024001-0037-y     Document Type: Article

References (28)

1. Wnt signaling: A common theme in animal development
2. WNTs modulate cell fate and behavior during vertebrate development
3. Wnt signalling in mammalian development and cancer
4. Isolation, characterization and embryonic expression of WNT11, a gene which maps to 11q13.5 and has possible roles in the development of skeleton, kidney and lung
5. Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4
6. The oncogenic activation of β-catenin
7. The role of beta-catenin in cell adhesion, signal transduction, and cancer
8. Identification of c-MYC as a target of the APC pathway
9. Beta-catenin regulates expression of cyclin D in colon carcinoma cells
10. The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3
11. Binding of GSK3 to the APC-beta-catenin complex and regulation of complex assembly
12. Negative regulation of Wingless signaling by D-axin, a Drosophila homolog of axin
13. Wnt-induced dephosphorylation of Axin release β-catenin from the Axin complex
14. The molecular basis of Turcot's syndrome
15. Close correlation between beta-catenin gene alterations and nuclear accumulation of the protein in human hepatocellular carcinomas
16. Mutations in the beta-catenin gene (CTNNB1) in endometrioid ovarian carcinomas
17. Frequent mutation and nuclear localization of beta-catenin in anaplastic thyroid carcinoma
18. Nuclear beta-catenin and the development of bilateral symmetry in normal and LiC1-exposed chick embryos
19. Fetal and postnatal development of the lung
20. Molecular mechanisms controlling lung morphogenesis
21. Growth and developmental regulation of wnt-2 (irp) gene in mesenchymal cells of fetal lung
22. Proteoglycans are required for maintenance of Wnt-11 expression in the ureter tips
23. Characterization of the complete genomic structure of the human WNT-5A gene, functional analysis of its promotor, chromosomal mapping, and expression in early human embryogenesis
24. Involvement of Wnt-5a in chondrogenic pattern formation in the chick limb bud
25. Successive formative stages of precartilaginous mesenchymal condensations in vitro: Modulation of cell adhesion by Wnt-7A and BMP-2
26. Targeted disruption of the Wnt2 gene results in placentation defects
27. Identification of a Wnt-responsive signal transduction pathway in primary endothelial cells
28. Nuclear localization and mutation of beta-catenin in medulloblastomas