Crystal structure of the soluble form of equinatoxin II, a pore-forming toxin from the sea anemone Actinia equina

Structure

Volumn 9, Issue 4, 2001, Pages 341-346

  Athanasiadis, Alekos ^a   Anderluh, Gregor ^b   Maček, Peter ^b   Turk, Dušan ^a  

^a JO EF STEFAN INSTITUTE   (Slovenia)

^b UNIVERSITY OF LJUBLJANA   (Slovenia)

Author keywords

Actinoporin; Cathion channel; Crystal structure; Equinatoxin II; Membrane pore; Soluble form

Indexed keywords

ARGININE; EQUINATOXIN; LYSINE;

ALPHA HELIX; ARTICLE; BETA SHEET; CONTROLLED STUDY; CRYSTAL STRUCTURE; HYDROPHOBICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN STRUCTURE; SEA ANEMONE;

AMINO ACID SEQUENCE; ANIMALS; CELL MEMBRANE PERMEABILITY; CNIDARIAN VENOMS; CRYSTALLOGRAPHY, X-RAY; CYTOTOXINS; ELECTROSTATICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SEA ANEMONES; SOLUBILITY;

ACTINIA EQUINA; ACTINIARIA; ANEMONE; BACTERIA (MICROORGANISMS); EUKARYOTA;

EID: 0034880806     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(01)00592-5     Document Type: Article

References (34)

1. A functional-phylogenetic classification system for transmembrane solute transporters
2. A new cytolysin from the sea anemone, Heteractis magnifica: Isolation, cDNA cloning and functional expression
3. Isolation and characterization of three lethal and hemolytic toxins from the sea anemone Actinia equina
4. Polypeptide cytolytic toxins from sea anemones (Actiniaria)
5. Pore formation by the sea anemone cytolysin equinatoxin II in red blood cells and model lipid membranes
6. Thy cytotoxic and cytolytic activity of equinatoxin II from the sea anemone Actinia equina
7. Effects of equinatoxin II from Actinia equina on isolated rat heart: The role of direct cardiotoxic effects in equinatoxin II lethality
8. Channel-forming toxins: Tales of transformation
9. Colicin E1 binding to membranes: Time-resolved studies of spin-labeled mutants
10. Organization of diphtheria toxin T domain in bilayers: A site-directed spin labeling study
11. Structure of staphylococcal alpha-hemolysin, a heptameric transmembrane pore
12. Crystal structure of the anthrax toxin protective antigen
13. The mechanism of membrane insertion for a cholesterol-dependent cytolysin: A novel paradigm for pore-forming toxins
14. Primary and secondary structure of a pore-forming toxin from the sea anemone, Actinia equina L. and its association with lipid vesicles
15. A structural census of the current population of protein sequences
16. Structure of a cholesterol-binding thio-activated cytolysin and a model of its membrane form
17. Two-dimensional crystallization on lipid monolayers and three-dimensional structure of sticholysin II, a cytolysin from the sea anemone Stichodactyla helianthus
18. Lysine 77 is a key residue in aggregation
19. N-terminal truncation mutagenesis of equinatoxin II, a pore-forming protein from the sea anemone Actinia equina
20. Sequence analysis of melittin from tryptic and peptic degradation
21. The structure of melittin
22. Structure-function studies of tryptophan mutants of equinatoxin II, a sea anemone pore-forming protein
23. Cysteine scanning mutagenesis of an eukaryotic pore-forming toxin from sea anemone: Topology in lipid membranes
24. Biochemical and cytotoxic properties of conjugates of transferrin with equinatoxin II, a cytolysin from a sea anemone
25. The CCP4 suite: Programs for protein crystallography
26. Maximum-likelihood refinement of heavy-atom parameters in the MIR and MAD methods
27. Methods used in the structure determination of bovine mitochondrial F1 ATPase
28. Protein structure comparison by alignment of distance matrices
29. Protein folding and association: Insights for the interfacial and thermodynamic properties of hydrocarbons
30. Raster3D: Photorealistic molecular graphics