Modulation of AMPA receptors by a novel organic nitrate

Canadian Journal of Physiology and Pharmacology

Volumn 79, Issue 5, 2001, Pages 422-429

  Toong, S ^a   Xiong, Z G ^a   Zavorin, S I ^a   Bai, D ^a   Orser, B A ^a   Thatcher, G R J ^a   Reynolds, J N ^a   MacDonald, J F ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

AMPA receptors; Desensitization; Organic nitrates

Indexed keywords

1 NITROOXY 2 THIOCYANATOETHANE; 1,2 BIS NITROOXY 3 THIOCYANATOPROPANE; 3 THIOCYANATOPROPANE 1,2 DIOL; 7 CHLORO 3,4 DIHYDRO 3 METHYL 2H 1,2,4 BENZOTHIADIAZINE 1,1 DIOXIDE; ALCOHOL DERIVATIVE; AMPA RECEPTOR; GLUTAMIC ACID; GLYCERYL TRINITRATE; GT 005; GT 013; GT 038; KAINIC ACID; ORGANIC NITRATE; UNCLASSIFIED DRUG; VASODILATOR AGENT;

ANIMAL CELL; ARTICLE; BRAIN NERVE CELL; CELL CULTURE; CELL ISOLATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; EVOKED RESPONSE; HIPPOCAMPUS; MEMBRANE CURRENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; STEADY STATE; SYNAPTIC TRANSMISSION;

EID: 0034871483     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/y01-009     Document Type: Article

References (23)

1. The waveform of synaptic transmission at hippocampal synapses is not determined by AMPA receptor desensitization
2. Molecular basis of NMDA receptor-coupled ion channel modulation by S- nitrosylation
3. Action of brief pulses of glutamate on AMPA/kainate receptors in patches from different neurones of rat hippocampal slices
4. Asynchronous release of synaptic vesicles determines the time course of the AMPA receptor-mediated EPSC
5. Changes of spontaneous miniature excitatory postsynaptic currents in rat hippocampal pyramidal cells induced by aniracetam
6. Glutamate receptor channels in isolated patches from CA1 and CA3 pyramidal cells of rat hippocampal slices
7. Isolation of neurons suitable for patch-clamping from adult mammalian central nervous systems
8. Cyclic GMP-dependent feedback inhibition of AMPA receptors is independent of PKG
9. Neuronal protection and destruction by NO
10. Psychological effects of a drug that facilitates brain AMPA receptors
11. Regulation of N-methyl-D-aspartate receptors revealed by intracellular dialysis of murine neurones in culture
12. AMPA receptor flip/flop mutants affecting deactivation, desensitization, and modulation by cyclothiazide, aniracetam, and thiocyanate
13. AMPA receptor flip/flop mutants affecting deactivation, desensitization, and modulation by cyclothiazide, aniracetam, and thiocyanate
14. Hippocampal neurons exhibit cyclothiazide-sensitive rapidly desensitizing responses to kainate
15. The mechanism of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor desensitization after removal of glutamate
16. Activation and desensitization of N-methyl-D-aspartate receptors in nucleated outside-out patches from mouse neurones
17. Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein
18. A novel allosteric potentiator of AMPA receptors: 4-[2-(phenylsulfonylamino)ethylthio]-2,6-difluoro-phenoxyacetamide
19. A novel nitrate ester reverses the cognitive impairment caused by scopolamine in the Morris water maze
20. NO problem for nitroglycerin: Organic nitrate chemistry and therapy
21. Modulation of excitatory synaptic transmission by drugs that reduce desensitization at AMPA/kainate receptors
22. Modulation by magnesium of the affinity of NMDA receptors for glycine in murine hippocampal neurones
23. Benzothiadiazides inhibit rapid glutamate receptor desensitization and enhance glutamatergic synaptic currents