A comparative study of antibody expressions in primary biliary cirrhosis and autoimmune cholangitis using phage display

Hepatology

Volumn 34, Issue 3, 2001, Pages 478-486

  Ikuno, Nobuhiro ^a,b   Scealy, Marita ^a   Davies, Janet M ^a   Whittingham, Senga F ^a   Omagari, Katsuhisa ^b   Mackay, Ian R ^a   Rowley, Merrill J ^a  

^a MONASH UNIVERSITY   (Australia)

^b NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; EPITOPE; IMMUNOGLOBULIN G; PEPTIDE LIBRARY; PROTEIN SUBUNIT; PYRUVATE DEHYDROGENASE COMPLEX; PYRUVATE DEHYDROGENASE COMPLEX E2 SUBUNIT ANTIBODY; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; AUTOIMMUNE DISEASE; CHOLANGITIS; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME CONFORMATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; PHAGE DISPLAY; PRIMARY BILIARY CIRRHOSIS; PRIORITY JOURNAL;

EID: 0034861384     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.2001.27013     Document Type: Article

References (46)

1. Primary biliary cirrhosis: Paradigm or paradox for autoimmunity
2. Autoimmune cholangitis and primary biliary cirrhosis - An autoimmune enigma
3. A cholangitis with antinuclear antibodies (immunocholangitis) resembling chronic destructive non-superative cholangitis
4. A 33-year-old woman with an autoimmune syndrome
5. Antimitochondrial antibody negative primary biliary cirrhosis: A distinct syndrome of autoimmune cholangitis
6. Primary autoimmune cholangitis: An alternative to antimitochondrial antibody-negative primary biliary cirrhosis
7. Antimitochondrial antibody-negative primary biliary cirrhosis
8. Autoimmune cholangitis: A variant of primary biliary cirrhosis. Clinicopathologic and serologic correlations in 200 cases
9. Autoimmune cholangitis syndrome with a bias towards primary biliary cirrhosis
10. Autoimmune cholangitis
11. Ludwig Symposium on biliary disorders. Autoimmune cholangitis: A unique entity?
12. Autoimmune cholangitis within the spectrum of autoimmune liver disease
13. The peculiar autoimmunity of primary biliary cirrhosis
14. Primary biliary cirrhosis: An orchestrated immune response against epithelial cells
15. Searching for peptide ligands with an epitope library
16. Discovering peptide ligands using epitope libraries
17. Epitope discovery using peptide libraries displayed on phage
18. Prediction of the immunodominant epitope of the pyruvate dehydrogenase complex E2 in primary biliary cirrhosis using phage display
19. Comparative immunoreactive profiles of Japanese and American patients with primary biliary cirrhosis against mitochondrial autoantigens
20. Immunoreactivity of antimitochondrial autoantibodies in Japanese patients with primary biliary cirrhosis
21. Primary biliary cirrhosis
22. Primary structure of the human M2 mitochondrial autoantigen of primary biliary cirrhosis: Dihydrolipoamide acetyltransferase
23. Multiple alignment and sorting of peptides derived from phage-displayed random peptide libraries with polyclonal sera allows discrimination of relevant phagotopes
24. Characterisation of epitopes for virus-neutralising monoclonal antibodies to ross river virus E2 using phage-displayed random peptide libraries
25. Improved tools for biological sequence comparison
26. The European Bioinformatics Institute (EBI) databases
27. Identification of major linear epitopes on the sp100 nuclear PBC autoantigen by the gene-fragment phage-display technology
28. Mimotopes identified by phage display for the monoclonal antibody CII-C1 to type II collagen
29. Monoclonal antibody screening of a phage-displayed random peptide library reveals mimotopes of chemokine receptor CCR5 with implications for the tertiary structure of the receptor and inhibition of macrophage tropic HIV-1 infection
30. Conformational epitopes on the diabetes autoantigen GAD65 identified by peptide phage display and molecular modeling
31. Three-dimensional structure of the major autoantigen in primary biliary cirrhosis
32. Anti-DNA antibody idiotypes in systemic lupus erythematosus
33. Induction of a systemic lupus erythematosus-like disease in mice by a common human anti-DNA idiotype
34. Anti-idiotype antibodies to anti-mitochondrial antibodies in the sera of patients with primary biliary cirrhosis
35. Anti-idiotypic antibodies to anti-PDC-E2 in primary biliary cirrhosis and normal subjects
36. A general strategy to identify mimctopes of pathological antigens using only random peptide libraries and human sera
37. Post-panning computer aided analysis of phagotope collections selected with neurocysticercosis patient polyclonal antibodies elicited by diverse and as yet unknown antigens: Separation of disease-relevant and irrelevant peptide sequences
38. Autoimmunity, microbial immunity and the immunological homunculus
39. The B cell response to autologous type II collagen: Biased V gene repertoire with V gene sharing and epitope shift
40. Identification of peptide specific for cerebrospinal fluid antibodies in multiple sclerosis by using phage libraries
41. Identification of new B cell epitopes in the sera of rheumatoid arthritis patients using a random nanopeptide phage library
42. Selection of phage-displayed peptides mimicking type 1 diabetes-specific epitopes
43. Identification of autoimmune thrombocytopenic purpura-related epitopes using phage-display peptide library
44. Analysis of T-cell receptor β of the T-cell clones reactive to the human PDC-E2 163-176 peptide in the contxt of HLA-DR53 in patients with primary biliary cirrhosis
45. Fine specificity of T cells reactive to human PDC-E2 163-176 peptide, the immunodominant autoantigen in primary biliary cirrhosis: Implications for molecular mimicry and cross-recognition among mitochondrial autoantigens