Transcription factor GATA3 and the human HDR syndrome

Cellular and Molecular Life Sciences

Volumn 58, Issue 9, 2001, Pages 1296-1300

  Van Esch, H ^a   Devriendt, K ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

DiGeorge; Embryonic development; GATA3; HDR syndrome; Transcription factor

Indexed keywords

TRANSCRIPTION FACTOR GATA 3;

DISEASE ASSOCIATION; EMBRYO DEVELOPMENT; GENE MUTATION; HUMAN; HYPOPARATHYROIDISM; KIDNEY MALFORMATION; PERCEPTION DEAFNESS; REVIEW;

VERTEBRATA;

EID: 0034856120     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/pl00000940     Document Type: Review

References (45)

1. Autosomal dominant familial hypoparathyroidism, sensorineural deafness, and renal dysplasia
2. Hypoparathyroidismus und innenohrschwerhorigkeit
3. Autosomal dominant familial hypoparathyroidism and sensorineural deafness without renal dysplasia
4. Familial nephrosis, nerve deafness, and hypoparathyroidism
5. Autosomal recessive hypoparathyroidism with renal insufficiency and developmental delay
6. C-group chromosome abnormality (10p-?): Occurrence in a child with multiple malformations
7. The phenotypic spectrum of the 10p deletion syndrome versus the classical DiGeorge syndrome
8. DiGeorge anomaly and chromosome 10p deletions: One or two loci?
9. Characterization of 10p deletions suggests two nonoverlapping regions contribute to the DiGeorge syndrome phenotype
10. An HDR (hypoparathyroidism, deafness, renal dysplasia) syndrome locus maps distal to the DiGeorge syndrome region on 10p13/14
11. Recurrent cerebral infarctions and del(10)(p14p15.1) de novo in HDR (hypoparathyroidism, sensorineural deafness, renal dysplasia) syndrome
12. Partial DiGeorge syndrome in two patients with a 10p rearrangement
13. GATA3 haplo-insufficiency causes human HDR syndrome
14. Structure and expression of the human GATA3 gene
15. Gotta have GATA
16. GATA4 transcription factor is required for ventral morphogenesis and heart tube formation
17. Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis
18. Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1
19. An early haematopoietic defect in mice lacking the transcription factor GATA-2
20. Elt-1, an embryonically expressed Caenorhabditis elegans gene homologous to the GATA transcription factor family
21. Sequence and expression of GLN3, a positive nitrogen regulatory gene of Saccharomyces cerevisiae encoding a protein with a putative zinc finger DNA-binding domain
22. Molecular evolution of the GATA family of transcription factors: Conservation within the DNA-binding domain
23. The sequence of the human genome
24. Embryonic expression and cloning of the murine GATA-3 gene
25. Temporal and spatial changes in GATA transcription factor expression are coincident with development of the chicken optic tectum
26. Expression of zebrafish GATA 3 (gta3) during gastrulation and neurulation suggests a role in the specification of cell fate
27. Expression of GATA-binding proteins during embryonic development in Xenopus laevis
28. Embryonic expression of the human GATA-3 gene
29. The GTA-3 gene is expressed during human kidney embryogenesis
30. Gata3 loss leads to embryonic lethality due to noradrenaline deficiency of the sympathetic nervous system
31. Transcription factor GATA-3 alters pathway selection of olivocochlear neurons and affects morphogenesis of the ear
32. Knock-in mutation of transcription factor GATA-3 into the GATA-1 locus: Partial rescue of GATA-1 loss of function in erythroid cells
33. The transcription factor GATA3 is a downstream effector of Hoxb1 specification in rhombomere 4
34. Partial rescue of GATA-3 by yeast artificial chromosome transgenes
35. Localization of distant urogenital system-, central nervous system-, and endocardium-specific transcriptional regulatory elements in the GATA-3 locus
36. FOG, a multitype zinc finger protein, act as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation
37. Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG
38. Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1
39. Mouse GATA-4: A retinoic acid-inducible GATA-binding transcription factor expressed in endodermally derived tissues and heart
40. Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis
41. Delineation of the critical deletion region for congenital heart defects, on chromosome 8p23.1
42. A syndrome of tricuspid atresia in mice with a targeted mutation of the gene encoding Fog-2
43. The zinc finger-containing transcription factors GATA-4, -5, and -6
44. Transcription factor GATA-3 is required for development of the T-cell lineage