Signal transducer and activator of transcription 1 in human muscle: Implications in inflammatory myopathies

American Journal of Pathology

Volumn 151, Issue 1, 1997, Pages 81-88

  Illa, Isabel ^a,b   Gallardo, Eduard ^a   Gimeno, Ramón ^a   Serrano, Carmen ^a   Ferrer, Isidre ^b   Juárez, Cándido ^a  

^a Hosp Uniuersitari de la Sta Creu I ^*  (Spain)

^b HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; TRANSCRIPTION FACTOR;

ARTICLE; CLINICAL ARTICLE; DERMATOMYOSITIS; GENE EXPRESSION REGULATION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPATHOGENESIS; MUSCLE BIOPSY; POLYMERASE CHAIN REACTION; POLYMYOSITIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

BLOTTING, WESTERN; DERMATOMYOSITIS; DNA-BINDING PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; MUSCLE, SKELETAL; MYOSITIS; POLYMYOSITIS; RHABDOMYOSARCOMA; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 0030848216     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Engel AG, Hohlfeld R, Banker BQ: The polymyositis and dermatomyositis syndromes, Myology, ed 2, Edited by AG Engel, Franzini-C Armstrong. New York, McGraw-Hill, 1994, pp 1335-1383
2. Dalakas MC: Polymyositis, dermatomyositis, and inclusion body myositis. N Engl J Med 1991, 325:1487-1498
3. Hohlfeld R, Engel AG: The immunobiology of muscle. Immunol Today 1994, 15:269-274
4. Paul WE, Seder RA: Lymphocyte response and cytokines. Cell 1994, 76:241-251
5. Aral K, Lee F, Miyajima A, Miyatake S, Aral N, Yokota T: Cytokines: coordinators of immune and inflammatory responses, Annu Rev Biochem 1990, 59:783-836
6. Emslie-Smith AM, Arahata K, Engel AG: Major histocompatibility complex class I antigen expression, immunolocalization of Interferon subtypes, and T cell- mediated cytotoxicity in myopathies, Hum Pathol 1989, 20:224-231
7. Lundberg I, Brengman JM, Engel AG: Analysis of cytokine expression in muscle in inflammatory myopathies, Duchenne dystrophy, and non-weak controls. J Neuroimmunol 1995, 63:9-16
8. Tews DS, Goebel HH: Cytokine expression profile in idiopathic inflammatory myopathies. J Neuropathol Exp Neurol 1996, 55:342-347
9. Lagoo AS, Lagoo-Deenadayalan S, Lorenz HM, Byrne J, Barber WH, Hardy KJ: II-2, II-4 and IFN-γ gene expression versus secretion in superantigen-activated T-cells: distinct requirement for costimulatory signals through adhesion molecules. J Immunol 1994, 152:1641-1652
10. Darnell JE, Kerr M, Stark GR: Jak-STAT pathways and transcription activation in response to IFNs and other extracellular signaling proteins. Science 1994, 264:1415-1421
11. Ihle N, Kerr M, Stark GR: Jaks and Stats in signaling the cytokine receptor superfamily, Trends Genet 1995, 11:69-74
12. Mui AL-F, Wakao H, O'Farrell M, Haradan N, Miyajima A: Interleukin-3, granulocyte-macrophage colony simulating factor and interleukin-5 transduce signals through two STAT5 homologs. EMBO J 1995, 14:1166- 1175
13. Schindler C, Shuai K, Prezioso VR, Darnell JE: Interferon dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor. Science 1992, 257:809-813
14. Schindler C, Shuai K, Prezioso VR, Darnell JE: Activation of transcription by IFM-γ: tyrosine phosphorylation of a 91 kDa DNA binding protein. Science 1992, 258:1808-1812
15. Larner AC, David M, Feldman GM, Igarashi K, Hackett RH, Webb DS, Sweitzer SM, Petricoin EF, Finbloom OS: Tyrosine phosphorylation of DNA binding proteins by multiple cytokines, Science 1993, 261:1730-1733
16. Ruff-Jamison S, Chen K, Cohen S: Induction by EGF and interferon-γ of tyrosine phosphorylated DNA binding proteins in mouse liver nuclei. Science 1993, 261:1733-1736
17. Silvennoien O, Schindler C, Schlessinger J, Levy DE: Ras-independent growth factor signaling by transcription factor tyrosine phosphorylation. Science 1993, 261:1736-1739
18. Sadowski HB, Shuai K, Darnell JE, Oilman MZ: A common nuclear signal transduction pathway activated by growth factors and cytoktne receptors. Science 1993, 261:1739-1744
19. Illa I, Leon-Monzon M, Dalakas MC: Regenerating and denervated human muscle fibers and satellite cells express neural cell adhesion molecules recognized by monoclonal antibodies to natural killer cells. Ann Neurol 1993, 31:46-52
20. Illa I, Dinsmore S, Dalakas MC: Immune-mediated mechanisms and immune activation of fibroblasts in the pathogenesis of eosinophilia-myalgia syndrome induced by L-tryptophan. Hum Pathol 1993, 24:702-709
21. Askanas V, Engel WK: A new program for investigating adult human skeletal muscle grown aneurally in tissue culture, Neurology 1975, 25:58-67
22. Schreiber E, Matthias P, Muller MM, Scaffner W: Rapid detection of octamer binding proteins with mini extracts prepared from a small number of cells, Nucleic Acids Res 1989, 17:6419
23. Laemmli UK: Cleavage of structural proteins during the assembly of the head of the bacteriophage T4. Nature 1970, 227:680-685
24. Towbin H, Staehelin T, Gordon J: Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 1979, 76:4350-4354
25. Gimeno R, Codony-Servat J, Plana M, Rodrfguez- Sánchez JL, Juárez C: Stat1 implication in the immune response to superantigens in vivo. J Immunol 1996, 156:1378-1386
26. Meraz MA, While JM, Sheehan KCF, Bach EA, Rodig SJ, Dighe AS, Kaplan DH, Riley JK, Greenland AC, Campbell D, Carver Moore K, Dubois RN, Clark R, Aguet M, Schreiber RD: Targeted disruption of Stat1 gene in mice reveals unexpected physiologic specificity in the Lak-STAT signaling pathway. Cell 1996, 84:431-442
27. Durbin JE, Hackenmiller R, Simon MC, Levy DE: Targeted disruption of the mouse Statl gene results in compromised innate immunity to viral disease. Cell 1996, 84:443-450
28. Ihle JN: STATs: signal transducers and activators of transcription. Cell 1996, 84:331-334
29. Pine R, Canova A, Schindler C: Tyrosine phosphorylated p91 binds to a single element in the ISGF/IRF-1 promoter to mediate induction by IFN-α and IFN-γ and is likely to autoregulate the p91 gene. EMBO J 1994, 13:158-167
30. Feldman GM, Chuang EJ, Finbloom DS: IgG immune complexes inhibit IFN-γ induced transcription of the FcγRI gene in human monocytes by preventing the tyrosine phosphorylation of the p91 (Stat1) transcription factor, J Immunol 1994, 154:318-325
31. Larner AC, Petricoin EF, Nakagawa Y, Finbloom DS: IL-4 attenuates the transcriptional activation of both IFN-α and IFN-γ induced cellular gene expression in monocytes and monocytic cell lines. J Immunol 1993, 150:1944-1950