Intrinsic versus extrinsic stabilization of enzymes: The interaction of solutes and temperature on A4-lactate dehydrogenase orthologs from warm-adapted and cold-adapted marine fishes

European Journal of Biochemistry

Volumn 268, Issue 16, 2001, Pages 4497-4505

  Fields, Peter A ^a   Wahlstrand, Benjamin D ^a   Somero, George N ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

Conformational microstates; Lactate dehydrogenase; Preferential exclusion; Stabilization; Thermal stability

Indexed keywords

A4 LACTATE DEHYDROGENASE; GLYCEROL; LACTATE DEHYDROGENASE ISOENZYME; MACROGOL 8000; PYRUVIC ACID; SUCROSE; TRIMETHYLAMINE OXIDE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING KINETICS; CATALYSIS; COLD ACCLIMATIZATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME STABILITY; EVOLUTION; FISH; HEAT ACCLIMATIZATION; MEASUREMENT; NONHUMAN; PRIORITY JOURNAL; SURFACE PROPERTY; TEMPERATURE;

ANIMALS; ENZYME STABILITY; FISHES; FLUORESCENCE; ISOENZYMES; L-LACTATE DEHYDROGENASE; PROTEIN CONFORMATION; TEMPERATURE;

EID: 0034825983     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2001.02374.x     Document Type: Article

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