Genetics of neural tube defects

Seminars in Pediatric Neurology

Volumn 8, Issue 3, 2001, Pages 160-164

  Gelineau Van Waes, Janee ^a,b   Finnell, Richard H ^a  

^a NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ACTIN; CARRIER PROTEIN; FOLATE RECEPTOR ALPHA; FOLIC ACID; METHIONINE SYNTHASE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; VITAMIN RECEPTOR;

GENETIC ANALYSIS; HUMAN; MATERNAL NUTRITION; METHYLATION; MITOSIS; MOLECULAR GENETICS; NEURAL TUBE DEFECT; NONHUMAN; PATHOGENESIS; REVIEW; RISK ASSESSMENT; VITAMIN METABOLISM; VITAMIN SUPPLEMENTATION;

EID: 0034825266     PISSN: 10719091     EISSN: None     Source Type: Journal    
DOI: 10.1053/spen.2001.26449     Document Type: Article

References (28)

1. Brain and spinal cord
2. Anencephaly: A review
3. Etiologic heterogeneity of neural tube defects
4. Neural tube defects: A review of human and animal studies on the etiology of neural tube defects
5. Periconceptional vitamin use, dietary folate, and the occurrence of neural tube defects
6. Racial variations in incidence of congenital malformations
7. Epidemiologic characteristics of phenotypically distinct neural tube defects among 0.7 million California births, 1983-1987
8. Mouse models for neural tube closure defects
9. Vitamin deficiencies and neural tube defects
10. Double-blind randomized controlled trial of folate treatment before conception to prevent recurrence of neural-tube defects
11. Prevention of neural tube defects: Results of the MRC vitamin study
12. Further experience of vitamin supplementation for prevention of neural tube defect recurrences
13. Delivery of folates to the cytoplasm of MA104 cells is mediated by a surface membrane receptor that recycles
14. Distribution of the folate receptor (gp 38) in normal and malignant cell lines and tissues
15. Mice lacking the folic acid binding protein Folbp1 are defective in early embryonic development
16. A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase
17. Decreased methylenetetrahydrofolate reductase activity due to the 677C-T mutation in families with spina bifida offspring
18. Maternal vitamin use, genetic variation of infant methylenetetrahydrofolate reductase, and risk for spina bifida
19. Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition
20. The folate receptor works in tandem with a probenecid-sensitive carrier in MA104 cells in vitro
21. The transmembrane pH gradient drives uphill folate transport in rabbit jejunum: Direct evidence for folate/hydroxyl exchange in brush border membrane vesicles
22. Rescue of embryonic lethality in reduced folate carrier-deficient mice by maternal folic acid supplementation reveals early neonatal failure of hematopoietic organs
23. Folate metabolism and neural tube defects: A review
24. Homocysteine metabolism in pregnancies complicated by neural tube defects
25. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
26. Vinculin knockout results in heart and brain defects during embryonic development