Decreased methylene tetrahydrofolate reductase activity due to the 677C→T mutation in families with spina bifida offspring

Journal of Molecular Medicine

Volumn 74, Issue 11, 1996, Pages 691-694

  Van Der Put, N M J ^a   Van Den Heuvel, L P ^a   Steegers Theunissen, R P M ^a   Trijbels, F J M ^a   Eskes, T K A B ^a   Mariman, E C M ^a   Den Heyer, M ^b   Blom, H J ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b LEYENBURG HOSPITAL   (Netherlands)

Author keywords

5,10 Methylene tetrahydrofolate reductase; Folate; Homocysteine; Risk factor; Spina bifida

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); FOLIC ACID; HOMOCYSTEINE;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME DEFICIENCY; FAMILY STUDY; FEMALE; GENE MUTATION; GENOTYPE; HUMAN; MALE; NEURAL TUBE DEFECT; RISK FACTOR; SPINA BIFIDA;

5,10-METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ADULT; AGED; CHILD; CYSTEINE; FEMALE; FOLIC ACID; GENOTYPE; HOMOCYSTEINE; HOMOZYGOTE; HUMANS; LINKAGE (GENETICS); LOD SCORE; LYMPHOCYTES; MALE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MIDDLE AGED; NETHERLANDS; OXIDOREDUCTASES; POINT MUTATION; RISK FACTORS; SPINAL DYSRAPHISM; VITAMIN B 12;

EID: 0029849703     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001090050073     Document Type: Article

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