Recombinant Semliki Forest virus vaccine vectors: The route of injection determines the localization of vector RNA and subsequent T cell response

Gene Therapy

Volumn 8, Issue 17, 2001, Pages 1307-1314

  Colmenero, P ^a   Berglund, P ^a   Kambayashi, T ^a   Biberfeld, P ^b   Liljestrom P ^a,c   Jondal, M ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c SWEDISH INSTITUTE FOR INFECTIOUS DISEASE CONTROL   (Sweden)

Author keywords

Immunization route; Recombinant vaccines; Semliki Forest virus; Viral vector

Indexed keywords

CAPSID PROTEIN; CD8 ANTIGEN; ENVELOPE PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; TETRAMER; VIRUS NUCLEOPROTEIN; VIRUS RNA; VIRUS VACCINE; VIRUS VECTOR;

ANIMAL CELL; ANIMAL MODEL; ANTIGEN SPECIFICITY; ARTICLE; CELL SPECIFICITY; CONTROLLED STUDY; CORRELATION FUNCTION; CYTOTOXIC T LYMPHOCYTE; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; FEMALE; GENE EXPRESSION; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INFLUENZA VIRUS A; INOCULATION; LYMPH NODE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEMLIKI FOREST ALPHAVIRUS; SPLEEN; T LYMPHOCYTE; VIRUS RECOMBINANT;

ANIMALS; BETA-GALACTOSIDASE; CELL LINE; CYTOTOXICITY TESTS, IMMUNOLOGIC; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; GENE THERAPY; GENETIC VECTORS; INJECTIONS, INTRAMUSCULAR; INJECTIONS, INTRAVENOUS; INJECTIONS, SUBCUTANEOUS; MICE; MICE, INBRED BALB C; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEMLIKI FOREST VIRUS; TISSUE DISTRIBUTION;

ALPHAVIRUS; ANIMALIA; INFLUENZA VIRUS; INFLUENZAVIRUS A; MIRIDAE; RABBIT FIBROMA VIRUS; RNA VIRUSES; SEMLIKI FOREST VIRUS;

EID: 0034823745     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301501     Document Type: Article

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