Changes in T cell subpopulations of sheep due to age and dietary protein intake; association with protective immunity to Trichostrongylus colubriformis

Veterinary Immunology and Immunopathology

Volumn 51, Issue 1-2, 1996, Pages 127-135

  Kambara, T ^a,b   McFarlane, R G ^b  

^a PFIZER INC   (United States)

^b LINCOLN UNIVERSITY   (New Zealand)

Author keywords

age; CD4; CD5; CD8; cellular immunity; dietary protein; gastrointestinal nematodes; resistance; sheep; T cell; T19; Trichostrongylus colubriformis

Indexed keywords

CD14 ANTIGEN; CD4 ANTIGEN; CD5 ANTIGEN; CD8 ANTIGEN;

AGE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DIET; HOST RESISTANCE; MALE; NONHUMAN; PARASITOSIS; PROTEIN INTAKE; SHEEP; T LYMPHOCYTE SUBPOPULATION; TRICHOSTRONGYLUS COLUBRIFORMIS;

EID: 0030008706     PISSN: 01652427     EISSN: None     Source Type: Journal    
DOI: 10.1016/0165-2427(95)05513-4     Document Type: Article

References (20)

1. Abbott, E.M., Parkins, J.J. and Holmes, P.H., 1988. Influence of dietary protein on the pathophysiology of Haemonchosis in lambs given continuous infections. Res. Vet. Sci., 45: 41-49.
2. Dineen, J.K., Ronai, P.M. and Wagland, B.M., 1968. The cellular transfer of immunity to Trichostrongylus colubriformis in an isogenic strain of guinea-pig. IV. The localization of immune lymphocytes in small intestine in infected and non-infected guinea-pig. Immunology, 15: 671-679.
3. Gibson, T.E. and Parfitt, J.W., 1972. The effect of age on the development by sheep of resistance to Trichostrongylus colubriformis. Res. Vet. Sci., 13: 529-535.
4. + T cells abrogates genetic resistance to Haemonchus contortus in sheep. Immunology, 78: 43-49.
5. Gorrell, M.D., Willis, G., Brandon, M.R. and Lascelles, A.K., 1988a. Lymphocyte phenotypes in the intestinal mucosa of sheep infected with Trichostrongylus colubriformis. Clin. Exp. Immunol., 72: 274-279.
6. Gorrell, M.D., Miller, H.R.P. and Brandon, M.R., 1988b. Lymphocyte phenotypes in the abomasal mucosa of sheep infected with Haemonchus contortus. Parasite Immunol., 10: 661-674.
7. Hein, W.R., Dudler, L. and Morris, B., 1990. Differential peripheral expansion and in vivo antigen reactivity of αβ and γδ T cells emigrating from the early fetal lamb thymus. Eur. J. Immunol., 20: 1805-1813.
8. Kambara, T., McFarlane, R.G., Abell, T.J., McAnulty, R.W. and Sykes, A.R., 1993. The effect of age and dietary protein on immunity and resistance in lambs vaccinated with Trichostrongylus colubriformis. Int. J. Parasitol., 23: 471-476.
9. Mackay, C., 1988. Sheep leucocyte molecules: a review of their distribution, structure and possible function. Vet. Immunol. Immunopathol., 19: 1-20.
10. Mackay, C.R., 1992. Altered patterns of T cell migration through lymph nodes and skin following antigen challenge. Eur. J. Immunol., 22: 2205-2210.
11. MacKay, C.R., Maddox, J.F., Gogolin-Ewens, K.J. and Brandon, M.R., 1985. Characterization of two sheep lymphocyte differentiation antigens SBU-T1 and SBU-T6. Immunology, 55: 729-737.
12. Maddox, J.F., Mackay, C.R. and Brandon, M.R., 1985. Surface antigens, SBU-T4 and SBU-T8, of sheep lymphocyte subsets defined by monoclonal antibodies. Immunology, 55: 739-749.
13. Manton, V.J.A., Peacock, B., Poynter, D., Silverman, P.H. and Terry, R.J., 1962. The influence of age on naturally acquired resistance to Haemonchus contortus in lambs. Res. Vet. Sci., 3: 308-314.
14. McClure, S.J., Wagland, B.M. and Emery, D.L., 1991. Effects of Freund's adjuvants on local, draining and circulating lymphocyte populations in sheep. Immunol. Cell Biol., 69: 361-367.
15. McClure, S.J., Emery, D.L., Wagland, B.M. and Jones, W.O., 1992. A serial study of rejection of Trichostrongylus colubriformis by immune sheep. Int. J. Parasitol., 22: 227-234.
16. Meeusen, E., Gorrell, M.D., Rickard, M.D. and Brandon, M.R., 1989. Lymphocyte subpopulations of sheep in protective immunity to Taenia hydatigena. Parasite Immunol., 11: 169-181.
17. + B cells in normal and Trypanosoma congolense-infected cattle. Eur. J. Immunol., 22: 1713-1718.
18. Smith, W.D., Jackson, F., Jackson, E., Graham, R., Williams, J., Willadsen, S.M. and Fehilly, C.B., 1986. Transfer of immunity to Ostertagia circumcincta and IgA memory between identical sheep by lymphocytes collected from gastric lymph. Res. Vet. Sci., 41: 300-306.
19. Soulsby, E.J.L., Monsell, G. and Lloyd, S., 1981. Acquisition of immunological competence to gastro-intestinal Trichostrongyles by young ruminants: epidemiological significance. In: P. Nansen, R.J. Jørgensen and E.J.L. Soulsby (Editors), Epidemiology and Control of Nematodiasis in cattle. ECSC, EEC, EAEC, Brussels-Luxembourg, pp. 513-529.
20. Watson, D.L., Colditz, I.G., Andrew, M., Gill, H.S. and Altmann, K.G., 1994. Age-dependent immune response in Merino Sheep. Res. Vet. Sci., 57: 152-158.