Intratype HPV16 sequence variation within LCR of isolates from asymptomatic carriers and cervical cancers

Journal of Clinical Virology

Volumn 23, Issue 1-2, 2001, Pages 65-77

  Schmidt, Marcin ^a   Kędzia, Witold ^b   Goździcka Józefiak, Anna ^a  

^a ADAM MICKIEWICZ UNIVERSITY   (Poland)

^b POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

Author keywords

Human Papillomavirus type 16; Persistent infection; Transcription factors; Variants

Indexed keywords

DNA; NUCLEOTIDE; OCTAMER TRANSCRIPTION FACTOR 1; REGULATOR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR E2; TRANSCRIPTION FACTOR NF1; TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR TEF 1; TRANSCRIPTION FACTOR TEF 2; TRANSCRIPTION FACTOR YY1; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CONTROLLED STUDY; FEMALE; GENE ISOLATION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC POLYMORPHISM; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN BINDING; RISK FACTOR; SEQUENCE ANALYSIS; SINGLE STRAND CONFORMATION POLYMORPHISM; TISSUE SECTION; UTERINE CERVIX CARCINOMA; UTERINE CERVIX CYTOLOGY; UTERINE CERVIX EPITHELIUM; VIRUS CARRIER; VIRUS INFECTION; VIRUS ISOLATION; WART VIRUS;

BINDING SITES; CARRIER STATE; CERVICAL INTRAEPITHELIAL NEOPLASIA; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FEMALE; HUMANS; LOCUS CONTROL REGION; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS INFECTIONS; TUMOR VIRUS INFECTIONS; UTERINE CERVICAL NEOPLASMS; VARIATION (GENETICS);

EID: 0034815149     PISSN: 13866532     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1386-6532(01)00189-5     Document Type: Article

References (59)

1. Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines
2. Nucleosome structural changes due to acetylation
3. Characterization of the human papillomavirus E2 protein: Evidence of trans-activation and trans-repression in cervical keratinocytes
4. Purification and biochemical characterization of the promoter-specific transcription factor, Sp1
5. Molecular variants of human papillomavirus type 16 from four continents suggest ancient pandemic spread of the virus and its coevolution with humankind
6. Analysis of genomic sequences of 95 papillomavirus types: Uniting typing, phylogeny, and taxonomy
7. Bovine papillomavirus type 1 encodes two forms of a transcription repressor: Structural and functional analysis of new viral cDNAs
8. Human CCAAT-binding proteins have heterologous subunits
9. Transcriptional activation of human papillomavirus 16 by nuclear factor I, AP1, steroid receptors and a possibly novel transcription factor, PVF: A model for the composition of genital papillomavirus enhancers
10. The enhancer of human papillomavirus type 16: Binding sites for the ubiquitous transcription factors Oct-1, NFA, TEF-2, NF1, and AP-1 participate in epithelial cell-specific transcription
11. Transcriptional regulation of the human papillomavirus-16 E6-E7 promoter by a keratinocyte-dependent enhancer, and by viral E2 trans-activator and repressor gene products: Implication for cervical carcinogenesis
12. Analysis by polymerase chain reaction of the physical state of human papillomavirus type 16 DNA in cervical preneoplastic and neoplastic lesions
13. Control of papillomavirus DNA replication and transcription
14. Prevalence of deletions of YY1-binding sites in episomal HPV16 DNA from cervical cancers
15. Overlapping YY1- and aberrant SP1-binding sites proximal to the early promoter of human papillomavirus type 16
16. The functional BPV-1 E2 trans-activating protein can act as a repressor by preventing formation of the initiation complex
17. A papillomavirus DNA from a cervical carcinoma and its prevalence in cancer biopsy samples from different geographic regions
18. Context-dependent transcriptional regulation
19. Structural and mutational analysis of E2 trans-activating proteins of papillomaviruses reveals three distinct functional domains
20. Functional characterisation of naturally occurring mutants of human papillomavirus type 16 with large deletions in the non-coding region
21. Cooperativity in vivo between the E2 transactivator and the TATA box binding protein depends on core promoter structure
22. Papillomavirus infections - A major cause of human cancers
23. Bovien papilloma virus-transformed cells contain multiple E2 proteins
24. Sequence analysis of the long control region of human papillomavirus type 16 variants and functional consequences for P97 promoter activity
25. Enhanced transcriptional activation by E2 proteins from the oncogenic human papillomaviruses
26. Enhancer-promoter activity of Human Papillomavirus type 16 Long Control Regions isolated from cell lines SiHa and CaSki and cervical cancer biopsies
27. A transcriptional repressor encoded by BPV-1 shares a common carboxy-terminal domain with the E2 transactivator
28. Genetic assignment of multiple E2 gene products in bovine papillomavirus transformed cells
29. Prolonged glucocorticoid exposure dephosphorylates histone H1 and inactivates the MMTV promoter
30. Synergistic transcriptional activation by papillomavirus E2 protein occurs after DNA binding and correlates with change in chromatine structure
31. Cellular transcription factors regulate human papillomavirus type 16 gene expression by binding to a subset of the DNA sequences recognized by the viral E2 protein
32. Expression of dominant negative Jun inhibits elevate AP-1 and NF-kappaB transactivation and suppresses anchorage independent growth of HPV immortalized human keratinocytes
33. The E6/E7 promoter of extrachromosomal HPV16 DNA in cervical cancers escapes from cellular repression by mutation of target sequences for YY1
34. Cervical Human Papillomavirus infection and intraepithelial neoplasia: A review
35. The binding of a Fos/Jun heterodimer can completely disrupt the structure of a nucleosome
36. Oct-1 activates the epithelial-specific enhancer of human papillomavirus type 16 via a synergistic interaction with NFI at a conserved composite regulatory element
37. Transcription factor binding sites in the long control regions of genital HPVs
38. YY1 represses human papillomavirus type 16 transcription by quenching AP-1 activity
39. Mutational and functional analysis of HPV-16 URR derived from Korean cervical neoplasia
40. Transcriptional trans-activation by the human papillomavirus type 16 E2 gene product
41. Mutational analysis of cis elements involved in E2 modulation of human papillomavirus type 16 P97 and type 18 P105 promoters
42. Production of human papillomavirus type 16 early proteins in Bac-To-Bac expression system
43. Everything you have ever wanted to know about Yin Yang 1
44. The enhancer in the long control region of human papillomavirus type 16 is up-regulated by PEF-1 and down-regulated by Oct-1
45. Transactivation of a bovine papilloma virus transcriptional regulatory element by the E2 gene product
46. Cloning of human RTEF-1, a transcriptional enhancer factor-1-related gene preferentially expressed in skeletal muscle: Evidence for an ancient multigene family
47. The chromatin structure of the long control region of Human Papillomavirus Type 16 represses viral oncoprotein expression
48. During negative regulation of the human papillomavirus-16 E6 promoter, the viral E2 protein can displace Sp1 from proximal promoter element
49. The human papillomavirus type16 E2 transcription factor binds with low cooperativity to two flanking sites and represses the E6 promoter through displacement of Sp1 and TFIID
50. Nuclear matrix attachment regions of Human Papillomavirus Type 16 point toward conservation of these genomic elements in all genital Papillomaviruses
51. DNA binding and bending by the Human Papillomavirus type 16 E2 protein Recognition of an extended binding site
52. The structure, function, and regulation of papillomaviral genes in infection and cervical cancer
53. Trans activation by full-length E2 proteins of human papillomavirus type 16 and bovine papillomavirus type 1 in vitro and in vivo: Cooperation with activation domains of cellular transcription factors
54. Transient replication of BPV-1 requires two viral polypeptides encoded by the E1 and E2 open reading frames
55. Functional significance of sequence variation in the E2 gene and the long control region of human papillomavirus type 16
56. Molecular diagnosis of Presistent Human Papilloma Virus infections
57. Genomic variation of human papillomavirus type 16 and risk for high grade cervical intraepithelial neoplasia
58. Risk of anal carcinoma in situ in relation to human papillomavirus type 16 variants
59. Human papillomavirus type 16 sequence variation in cervical cancers: A worldwide perspective