Characterization of the promoter region of the human peroxisomal multifunctional enzyme type 2 gene

Biochemical and Biophysical Research Communications

Volumn 284, Issue 1, 2001, Pages 226-231

  Novikov, Dmitry K ^a   Kamps, Marika E ^a  

^a UNIVERSITY OF OULU   (Finland)

Author keywords

AP2; Bile acids; Peroxisomes; Sp1

Indexed keywords

BILE ACID; CHOLESTEROL; ENZYME; LUCIFERASE; PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG;

ARTICLE; BILE ACID SYNTHESIS; BINDING SITE; CELL STRAIN HEPG2; CONTROLLED STUDY; GENE FUNCTION; GENE STRUCTURE; GENETIC TRANSFECTION; HELA CELL; HUMAN; HUMAN CELL; LIPID OXIDATION; PEROXISOME; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

EID: 0034810651     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.4949     Document Type: Article

References (21)

1. Peroxisomal oxidation of the steroid side chain in bile acid formation
2. In vitro formation of bile acids from di- and trihydroxy-5 beta-cholestanoic acid in human liver peroxisomes
3. Role and organization of peroxisomal beta-oxidation
4. The CoA esters of 2-methyl-branched chain fatty acids and of the bile acid intermediates di- and trihydroxycoprostanic acids are oxidized by one single peroxisomal branched chain acyl-CoA oxidase in human liver and kidney
5. The human peroxisomal multifunctional protein involved in bile acid synthesis: Activity measurement, deficiency in Zellweger syndrome and chromosome mapping
6. Substrate specificities of 3-oxoacyl-CoA thiolase A and sterol carrier protein 2/3-oxoacyl-CoA thiolase purified from normal rat liver peroxisomes. Sterol carrier protein 2/3-oxoacyl-CoA thiolase is involved in the metabolism of 2-methyl-branched fatty acids and bile acid intermediates
7. Roles of PPARs in health and disease
8. Databases on transcriptional regulation: TRANSFAC, TRRD and COMPEL
9. AP2alpha and AP2gamma: A comparison of binding site specificity and trans-activation of the estrogen receptor promoter and single site promoter constructs
10. Structure of the gene for the human 17beta-hydroxysteroid dehydrogenase type IV
11. Further characterization of the peroxisomal 3-hydroxyacyl-CoA dehydrogenases from rat liver. Relationship between the different dehydrogenases and evidence that fatty acids and the C27 bile acids di- and trihydroxycoprostanic acids are metabolized by separate multifunctional proteins
12. The Sp-family of transcription factors
13. Novel role for Sp1 in phorbol ester enhancement of human platelet thromboxane receptor gene expression
14. Nuclear protein interactions with the human KDR/flk-1 promoter in vivo. Regulation of Sp1 binding is associated with cell type-specific expression
15. 2+-ATPase gene promoter are required for expression in Sol8 muscle cells
16. Recombinant 2-enoyl-CoA hydratase derived from rat peroxisomal multifunctional enzyme 2: Role of the hydratase reaction in bile acid synthesis
17. Two regulatory proteins that bind to the basic transcription element (BTE), a GC box sequence in the promoter region of the rat P-4501A1 gene
18. Identification of a novel TGF-beta-regulated gene encoding a putative zinc finger protein in human osteoblasts
19. Molecular cloning and characterization of TIEG2 reveals a new subfamily of transforming growth factor-beta-inducible Sp1-like zinc finger-encoding genes involved in the regulation of cell growth
20. Characterization of a dimerization motif in AP-2 and its function in heterologous DNA-binding proteins
21. Basic transcription element binding protein (BTEB) transactivates the cholesterol 7 alpha-hydroxylase gene (CYP7A)